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Secondary Fracture Prevention : Consensus Clinical Recommendations from a Multistakeholder Coalition

Conley, Robert B. (författare)
Center for Medical Technology Policy
Adib, Gemma (författare)
Osteoporosis Centre
Adler, Robert A. (författare)
Veterans Health Administration
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Åkesson, Kristina E. (författare)
Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups
Alexander, Ivy M. (författare)
University of Connecticut
Amenta, Kelly C. (författare)
Mercyhurst University
Blank, Robert D. (författare)
Garvan Institute of Medical Research,Medical College of Wisconsin
Brox, William Timothy (författare)
University of California, San Francisco
Carmody, Emily E. (författare)
University of Rochester
Chapman-Novakofski, Karen (författare)
University of Illinois at Urbana-Champaign
Clarke, Bart L. (författare)
Mayo Clinic Minnesota
Cody, Kathleen M. (författare)
American Bone Health
Cooper, Cyrus (författare)
University of Southampton
Crandall, Carolyn J. (författare)
University of California, Los Angeles
Dirschl, Douglas R. (författare)
University of Chicago Medical Center
Eagen, Thomas J. (författare)
National Council on Aging
Elderkin, Ann L. (författare)
American Society for Bone and Mineral Research
Fujita, Masaki (författare)
International Osteoporosis Foundation, Switzerland
Greenspan, Susan L. (författare)
University of Pittsburgh
Halbout, Philippe (författare)
International Osteoporosis Foundation, Switzerland
Hochberg, Marc C. (författare)
Slotervaart Hospital
Javaid, Muhammad (författare)
University of Oxford
Jeray, Kyle J. (författare)
Greenville Hospital System
Kearns, Ann E. (författare)
Mayo Clinic Minnesota
King, Toby (författare)
United States Bone and Joint Initiative (USBJI)
Koinis, Thomas F. (författare)
Duke Primary Care Oxford
Koontz, Jennifer Scott (författare)
Newton Medical Center,University of Kansas School of Medicine
Kužma, Martin (författare)
University Hospital in Bratislava
Lindsey, Carleen (författare)
Bristol Physical Therapy, LLC
Lorentzon, Mattias (författare)
Sahlgrenska Academy,Sahlgrenska University Hospital,Australian Catholic University
Lyritis, George P. (författare)
Hellenic Osteoporosis Foundation
Michaud, Laura Boehnke (författare)
University of Texas
Miciano, Armando (författare)
Nevada Rehabilitation Institute
Morin, Suzanne N. (författare)
McGill University
Mujahid, Nadia (författare)
Brown University
Napoli, Nicola (författare)
University Campus Bio-Medico,Washington University in St. Louis
Olenginski, Thomas P. (författare)
Geisinger Health System
Puzas, J. Edward (författare)
University of Rochester
Rizou, Stavroula (författare)
Hellenic Osteoporosis Foundation
Rosen, Clifford J. (författare)
Maine Medical Center Research Institute,Tufts University School of Medicine
Saag, Kenneth (författare)
University of Alabama
Thompson, Elizabeth (författare)
National Osteoporosis Foundation
Tosi, Laura L. (författare)
Children’s National Health System, Washington
Tracer, Howard (författare)
Agency for Healthcare Research and Quality
Khosla, Sundeep (författare)
Mayo Clinic Minnesota
Kiel, Douglas P. (författare)
Harvard Medical School
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 (creator_code:org_t)
2020
2020
Engelska 17 s.
Ingår i: Orthopaedic Nursing. - 0744-6020. ; 39:3, s. 145-161
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Osteoporosis-related fractures are undertreated, due in part to misinformation about recommended approaches to patient care and discrepancies among treatment guidelines. To help bridge this gap and improve patient outcomes, the American Society for Bone and Mineral Research assembled a multistakeholder coalition to develop clinical recommendations for the optimal prevention of secondary fracture among people aged 65 years and older with a hip or vertebral fracture. The coalition developed 13 recommendations (7 primary and 6 secondary) strongly supported by the empirical literature. The coalition recommends increased communication with patients regarding fracture risk, mortality and morbidity outcomes, and fracture risk reduction. Risk assessment (including fall history) should occur at regular intervals with referral to physical and/or occupational therapy as appropriate. Oral, intravenous, and subcutaneous pharmacotherapies are efficacious and can reduce risk offuture fracture. Patients need education, however, about the benefits and risks of both treatment and not receiving treatment. Oral bisphosphonates alendronate and risedronate are first-line options and are generally well tolerated; otherwise, intravenous zoledronic acid and subcutaneous denosumab can be considered. Anabolic agents are expensive but may be beneficial for selected patients at high risk. Optimal duration of pharmacotherapy is unknown but because the riskfor second fractures is highest in the early post-fracture period, prompt treatment is recommended. Adequate dietary or supplemental vitamin D and calcium intake should be assured. Individuals being treated for osteoporosis should be reevaluated for fracture risk routinely, including via patient education about osteoporosis and fractures and monitoring foradverse treatment effects. Patients should be strongly encouraged to avoid tobacco, consume alcohol in moderation at most, and engage in regular exercise and fall prevention strategies. Finally, referral to endocrinologists or other osteoporosis specialists may be warranted for individuals who experience repeated fracture or bone loss and those with complicating comorbidities (eg, hyperparathyroidism, chronic kidney disease). (c) 2019 American Society for Bone and Mineral Research.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Ortopedi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Orthopaedics (hsv//eng)

Nyckelord

aging
anabolics
antiresorptives
osteoporosis
secondary fracture prevention

Publikations- och innehållstyp

art (ämneskategori)
ref (ämneskategori)

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