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Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.
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- Goncalves, Isabel (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Kardiovaskulär forskning - translationella studier,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups,Cardiovascular Research - Translational Studies
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- Bengtsson, Eva (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - matrix och inflammation i ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Matrix and Inflammation in Atherosclerosis,Lund University Research Groups
- Colhoun, Helen M (author)
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- Shore, Angela C (author)
- Palombo, Carlo (author)
- Natali, Andrea (author)
- Aizawa, Kunihiko (author)
- Casanova, Francesco (author)
- Gooding, Kim (author)
- Strain, David (author)
- Kahn, Faisel (author)
- Looker, Helen C (author)
- Adams, Fiona (author)
- Belch, Jill (author)
- Pinnoli, Silvia (author)
- Venturi, Elena (author)
- Kozakova, Michaela (author)
- Gan, Li-Ming (author)
- Schnecke, Volker (author)
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- (creator_code:org_t)
- 2015
- 2015
- English.
- In: Arteriosclerosis, Thrombosis and Vascular Biology. - 1524-4636. ; 35:7, s. 1723-1731
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Matrix metalloproteinases (MMPs) degrade extracellular matrix proteins and play important roles in development and tissue repair. They have also been shown to have both protective and pathogenic effects in atherosclerosis, and experimental studies have suggested that MMP-12 contributes to plaque growth and destabilization. The objective of this study was to investigate the associations between circulating MMPs, atherosclerosis burden, and incidence of cardiovascular disease with a particular focus on type 2 diabetes mellitus.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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- Arteriosclerosis, Thrombosis and Vascular Biology (Search for host publication in LIBRIS)
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- Gooding, Kim
- Strain, David
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- Adams, Fiona
- Belch, Jill
- Pinnoli, Silvia
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- Gan, Li-Ming
- Schnecke, Volker
- Nilsson, Jan
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