Tyck till om SwePub Sök här!
LAR1:gu
Sökning: LAR1:gu > Dahlöf Björn 1953 > Gerdts E. > Fyhrquist F > Association of hemo...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Association of hemoglobin delivery with left ventricular structure and function in hypertensive patients: Losartan Intervention for End Point Reduction in Hypertension Study
- Narayan, P. (författare)
- Papademetriou, V. (författare)
- Wachtell, K. (författare)
- visa fler...
- Gerdts, E. (författare)
- Boman, K. (författare)
- Nieminen, M. S. (författare)
- de Simone, G. (författare)
- Fyhrquist, F. (författare)
- Hoieggen, A. (författare)
- Devereux, R. B. (författare)
- visa färre...
- (creator_code:org_t)
- 2006
- 2006
- Engelska.
- Ingår i: Hypertension. - 1524-4563. ; 47:5, s. 868-73
- Tidskriftsartikel (refereegranskat)
Abstract
Ämnesord
Stäng
- Several studies have shown associations of high levels of hemoglobin (Hgb) or blood viscosity with cardiac events and with left ventricular (LV) hypertrophy (LVH). To assess the relations of LV mass and function with Hgb delivery (ie, the physiological carrier of oxygen), we calculated the product of Hgb concentration and Doppler-derived cardiac output in 864 hypertensive participants with electrocardiographic LVH (359 women) in the Losartan Intervention for End Point Reduction in Hypertension echocardiography substudy. Among women, Hgb delivery was positively related to internal dimension, septal and posterior wall thicknesses, LV mass, endocardial and midwall fractional shortening, and peak A wave velocity and negatively to total peripheral resistance index, E/A ratio, deceleration time, and the isovolumic relaxation time. Among men, Hgb delivery was positively related to LV internal dimension, LV mass, and A velocity, and negatively to LV midwall shortening, relative wall thickness, peripheral resistance index, and E/A ratio. In multivariable analyses that adjusted for age, diastolic blood pressure, body mass index, and total cholesterol, hemoglobin delivery in women was related positively to LV fractional shortening, midwall shortening, LV mass mitral valve A velocity, and LV internal dimension and negatively to mitral valve deceleration time and isovolumic relaxation time. Among men, Hgb delivery had positive independent relations to mitral valve A velocity, LV internal dimension, midwall shortening, and LV mass and negative relations to the E/A ratio and relative wall thickness. Thus, in hypertensive LVH, higher oxygen delivery capacity is associated with higher LV mass and impaired early diastolic LV filling.
Nyckelord
- Aged
- Aged
- 80 and over
- Antihypertensive Agents/*therapeutic use
- Blood Flow Velocity
- Cardiac Output
- Echocardiography
- Female
- Hemoglobins/*metabolism
- Humans
- Hypertension/blood/complications/*drug
- therapy/*physiopathology/ultrasonography
- Hypertrophy
- Left Ventricular/etiology/physiopathology/*ultrasonography
- Losartan/*therapeutic use
- Male
- Middle Aged
- Mitral Valve/physiopathology
- Multivariate Analysis
- Myocardial Contraction
- Osmolar Concentration
- Sex Characteristics
- *Ventricular Function
- Left
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Narayan, P.
- Papademetriou, V ...
- Wachtell, K.
- Gerdts, E.
- Boman, K.
- Nieminen, M. S.
- visa fler...
- de Simone, G.
- Dahlöf, Björn, 1 ...
- Fyhrquist, F.
- Hoieggen, A.
- Devereux, R. B.
- visa färre...
- Artiklar i publikationen
- Hypertension
- Av lärosätet
- Göteborgs universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
