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Associations Between Oral Health and Risk of Dementia in a 37-Year Follow-Up Study: The Prospective Population Study of Women in Gothenburg

Stewart, R. (author)
Stenman, Ulrika (author)
Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
Hakeberg, Magnus, 1954 (author)
Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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Hägglin, Catharina, 1955 (author)
Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
Gustafson, Deborah, 1966 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Skoog, Ingmar, 1954 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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 (creator_code:org_t)
2015-01-17
2015
English.
In: Journal of the American Geriatrics Society. - : Wiley. - 0002-8614. ; 63:1, s. 100-105
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • ObjectivesTo investigate the association between incident dementia and previous number of teeth measured over a long interval. ParticipantsWomen with (n=158) and without (n=539) dementia in 2000 to 2005. MeasurementsTooth counts in 1968-69, 1980-81, and 1992-93. Covariates included age, education, stroke, myocardial infarction, diabetes mellitus, smoking status, blood pressure, body mass index, and cholesterol level. ResultsAfter adjustment for age, odds ratios (ORs) for dementia in 2000-05, comparing first with fourth tooth count quartiles, were 1.81 (95% confidence interval (CI)=1.03-3.19) for tooth counts measured in 1968, 2.25 (95% CI=1.18-4.32) for those in 1980, and 1.99 (0.92-4.30) for those in 1992. After further adjustment for education, ORs were 1.40 (95% CI=1.03-3.19) for 1968, 1.96 (95% CI=0.98-3.95) for 1980, and 1.59 (95% CI=0.71-3.53) for 1992, and after additional adjustment for vascular risk factors, ORs were 1.38 (95% CI=0.74-2.58) for 1968, 2.09 (95% CI=1.01-4.32) for 1980, and 1.61 (95% CI=0.70-3.68) for 1992. ConclusionIn most of the analyses, lower tooth count was not associated with dementia, although a significant association was found for one of the three examinations. Further research may benefit from more-direct measures of dental and periodontal disease.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Geriatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Geriatrics (hsv//eng)

Keyword

dementia
tooth loss
oral health
periodontal disease
cohort study
ALZHEIMERS-DISEASE
COGNITIVE IMPAIRMENT
GENERAL DESIGN
DENTAL-HEALTH
EDENTULISM
NUTRITION
MORTALITY
DECLINE
PURPOSE
PEOPLE
Geriatrics & Gerontology
Gerontology

Publication and Content Type

ref (subject category)
art (subject category)

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