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Sökning: WFRF:(Hartman Catharina A.) > Lunds universitet > (2022) > Cardiovascular risk...

Cardiovascular risk factors in attention-deficit/hyperactivity disorder : A family design study of Swedish conscripts

Garcia-Argibay, Miguel, 1988- (författare)
Örebro University,Karolinska Institute,Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Du Rietz, Ebba (författare)
Karolinska Institute,Karolinska Institutet
Hartman, Catharina A. (författare)
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Lichtenstein, Paul (författare)
Karolinska Institute,Karolinska Institutet
Chang, Zheng (författare)
Karolinska Institute,Karolinska Institutet
Fava, Cristiano (författare)
Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,University of Verona
Cortese, Samuele (författare)
School of Psychology, University of Southampton, Southampton, UK; Faculty of Medicine, Clinical and Experimental Science (CNS and Psychiatry), University of Southampton, Southampton, Hampshire, UK. 8 Solent NHS Trust, Southampton, UK; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, New York, USA; School of Medicine, Division of Psychiatry and Applied Psychology, University of Nottingham, Nottingham, UK
Larsson, Henrik, 1975- (författare)
Örebro University,Karolinska Institute,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
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 (creator_code:org_t)
2022-06-29
2022
Engelska.
Ingår i: International Journal of Methods in Psychiatric Research. - : John Wiley & Sons. - 1049-8931 .- 1557-0657. ; 31:4
Relaterad länk:
https://doi.org/10.1...
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https://oru.diva-por... (primary) (Raw object)
http://dx.doi.org/10... (free)
https://urn.kb.se/re...
https://doi.org/10.1...
http://kipublication...
https://lup.lub.lu.s...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Objective: (1) investigate the associations of attention-deficit/hyperactivity disorder (ADHD) with systolic and diastolic blood pressure, resting heart rate, pulse pressure (PP), physical fitness, and BMI; (2) explore whether cardiovascular risk factors and ADHD share genetic and environmental influences; (3) assess if pharmacological treatment for ADHD influences these associations.Methods: We identified 395,978 individuals born between 1973 and 1991 who had military conscription examinations at a mean age of 18.3 years (SD = 0.57) and their full-siblings within the same cohort (N = 208,060) by linking population-based registers in Sweden. Results Significantly increased risk of ADHD was observed in individuals with low systolic blood pressure (SBP) and PP, low physical fitness, and in those who had overweight or obesity after adjustments (adjusted Odds Ratio [OR] ranging from 1.10 to 1.45). Full siblings of individuals with low SBP, low physical fitness, and obesity were more likely to receive an ADHD diagnosis compared to full siblings without those risk factors (OR ranging from 1.17 to 1.31). Additionally, analyses showed robust associations between ADHD and low SBP, low physical fitness, and obesity, even in ADHD medication-naïve individuals.Conclusions: Individuals with several cardiovascular risk factors are more often diagnosed with ADHD, regardless of psychiatric comorbidity. These association are not explained by ADHD pharmacotherapy, rather, they are in part due to shared familial risk factors.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Allmänmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- General Practice (hsv//eng)

Nyckelord

Attention deficit hyperactivity disorder
blood pressure
cardiovascular risk factors
physical fitness
resting heart rate
Psychiatry
Psykiatri
Medicine
Medicin
attention deficit hyperactivity disorder
blood pressure
cardiovascular risk factors
physical fitness
resting heart rate

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