Pancreatic Islet Cells in Experimental Hypo- and Hyperparathyroidism in Rats

• The hypocalcaemic effect of glucagon is well documentedin the literature. In this investigation the pancreatic isletcells were studied in hypocalcaemic (parathyroidectomized)and hypercalcaemic (parathyroid hormone treated) rats.Observations were made after 1 and 8 weeks of hypocalcaemiaand after 3 days of hypercalcaemia. No qualitativeor quantitative changes in the islet cells were observed. Theresults are discussed.

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