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Sökning: onr:"swepub:oai:lup.lub.lu.se:6d835d4d-f89e-417e-a446-f2365761310e" > Clinically meaningf...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004113naa a2200469 4500
001oai:lup.lub.lu.se:6d835d4d-f89e-417e-a446-f2365761310e
003SwePub
008160401s2015 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/54566602 URI
024a https://doi.org/10.1016/j.parkreldis.2015.04.0292 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Puschmann, Andreasu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Klinisk neurogenetik,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Neurogenetics,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-aps
2451 0a Clinically meaningful parameters of progression and long-term outcome of Parkinson disease: An international consensus statement.
264 1b Elsevier BV,c 2015
338 a electronic2 rdacarrier
520 a Parkinson disease (PD) is associated with a clinical course of variable duration, severity, and a combination of motor and non-motor features. Recent PD research has focused primarily on etiology rather than clinical progression and long-term outcomes. For the PD patient, caregivers, and clinicians, information on expected clinical progression and long-term outcomes is of great importance. Today, it remains largely unknown what factors influence long-term clinical progression and outcomes in PD; recent data indicate that the factors that increase the risk to develop PD differ, at least partly, from those that accelerate clinical progression and lead to worse outcomes. Prospective studies will be required to identify factors that influence progression and outcome. We suggest that data for such studies is collected during routine office visits in order to guarantee high external validity of such research. We report here the results of a consensus meeting of international movement disorder experts from the Genetic Epidemiology of Parkinson's Disease (GEO-PD) consortium, who convened to define which long-term outcomes are of interest to patients, caregivers and clinicians, and what is presently known about environmental or genetic factors influencing clinical progression or long-term outcomes in PD. We propose a panel of rating scales that collects a significant amount of phenotypic information, can be performed in the routine office visit and allows international standardization. Research into the progression and long-term outcomes of PD aims at providing individual prognostic information early, adapting treatment choices, and taking specific measures to provide care optimized to the individual patient's needs.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
700a Brighina, Laura4 aut
700a Markopoulou, Katerina4 aut
700a Aasly, Jan4 aut
700a Chung, Sun Ju4 aut
700a Frigerio, Roberta4 aut
700a Hadjigeorgiou, Georgios4 aut
700a Kõks, Sulev4 aut
700a Krüger, Rejko4 aut
700a Siuda, Joanna4 aut
700a Wider, Christian4 aut
700a Zesiewicz, Theresa A4 aut
700a Maraganore, Demetrius M4 aut
710a Neurologi, Lundb Sektion IV4 org
773t Parkinsonism & Related Disordersd : Elsevier BVg 21:7, s. 675-682q 21:7<675-682x 1873-5126x 1353-8020
856u https://portal.research.lu.se/files/1562335/8519087.pdfx primaryx freey FULLTEXT
856u http://www.ncbi.nlm.nih.gov/pubmed/25952959?dopt=Abstracty FULLTEXT
856u http://dx.doi.org/10.1016/j.parkreldis.2015.04.029y FULLTEXT
856u https://lup.lub.lu.se/search/files/1562335/8519087.pdf
8564 8u https://lup.lub.lu.se/record/5456660
8564 8u https://doi.org/10.1016/j.parkreldis.2015.04.029

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