What Is the Role of the Placebo Effect for Pain Relief in Neurorehabilitation?: Clinical Implications From the Italian Consensus Conference on Pain in Neurorehabilitation

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What Is the Role of the Placebo Effect for Pain Relief in Neurorehabilitation? : Clinical Implications From the Italian Consensus Conference on Pain in Neurorehabilitation

Castelnuovo, Gianluca (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;Catholic Univ Milan, Dept Psychol, Milan, Italy.

Giusti, Emanuele Maria (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;Catholic Univ Milan, Dept Psychol, Milan, Italy.

Manzoni, Gian Mauro (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;eCampus Univ, Fac Psychol, Novedrate, Italy.

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Saviola, Donatella (författare): Santo Stefano Rehabil Ist, Cardinal Ferrari Rehabil Ctr, Fontanellato, Italy.

Gabrielli, Samantha (författare): San Pio X Clin, Pain Med Ctr, Humanitas, Milan, Italy.

Lacerenza, Marco (författare): San Pio X Clin, Pain Med Ctr, Humanitas, Milan, Italy.

Pietrabissa, Giada (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;Catholic Univ Milan, Dept Psychol, Milan, Italy.

Cattivelli, Roberto (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;Catholic Univ Milan, Dept Psychol, Milan, Italy.

Spatola, Chiara Anna Maria (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;Catholic Univ Milan, Dept Psychol, Milan, Italy.

Rossi, Alessandro (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.

Varallo, Giorgia (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.

Novelli, Margherita (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.

Villa, Valentina (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.

Luzzati, Francesca (författare): IRCCS Galeazzi Orthoped Inst, Milan, Italy.

Cottini, Andrea (författare): IRCCS Galeazzi Orthoped Inst, Milan, Italy.

Lai, Carlo (författare): Sapienza Univ Rome, Dept Dynam & Clin Psychol, Rome, Italy.

Volpato, Eleonora (författare): Catholic Univ Milan, Dept Psychol, Milan, Italy.;IRCCS Fdn Don Carlo Gnocchi, HD Resp Rehabil Unit, Milan, Italy.

Cavalera, Cesare (författare): Catholic Univ Milan, Dept Psychol, Milan, Italy.

Pagnini, Francesco (författare): Catholic Univ Milan, Dept Psychol, Milan, Italy.;Harvard Univ, Dept Psychol, 33 Kirkland St, Cambridge, MA 02138 USA.

Tesio, Valentina (författare): Univ Turin, Dept Psychol, Turin, Italy.

Castelli, Lorys (författare): Univ Turin, Dept Psychol, Turin, Italy.

Tavola, Mario (författare): ASST Lecco, Anesthesia & Intens Care, Lecce, Italy.

Torta, Riccardo (författare): Univ Turin, Dept Neurosci Rita Levi Montalcini, Turin, Italy.

Arreghini, Marco (författare): San Giuseppe Hosp, Rehabil Unit, Ist Auxol Italiano IRCCS, Verbania, Italy.

Zanini, Loredana (författare): San Giuseppe Hosp, Rehabil Unit, Ist Auxol Italiano IRCCS, Verbania, Italy.

Brunani, Amelia (författare): San Giuseppe Hosp, Rehabil Unit, Ist Auxol Italiano IRCCS, Verbania, Italy.

Seitanidis, Ionathan (författare): San Giuseppe Hosp, Rehabil Unit, Ist Auxol Italiano IRCCS, Verbania, Italy.

Ventura, Giuseppe (författare): San Giuseppe Hosp, Rehabil Unit, Ist Auxol Italiano IRCCS, Verbania, Italy.

Capodaglio, Paolo (författare): San Giuseppe Hosp, Rehabil Unit, Ist Auxol Italiano IRCCS, Verbania, Italy.

D'Aniello, Guido Edoardo (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;Catholic Univ Milan, Dept Psychol, Milan, Italy.

Scarpina, Federica (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.

Brioschi, Andrea (författare): San Giuseppe Hosp, Dept Neurol & Neurorehabil, Ist Auxol Italiano IRCCS, Verbania, Italy.

Bigoni, Matteo (författare): San Giuseppe Hosp, Dept Neurol & Neurorehabil, Ist Auxol Italiano IRCCS, Verbania, Italy.

Priano, Lorenzo (författare): Univ Turin, Dept Neurosci Rita Levi Montalcini, Turin, Italy.;San Giuseppe Hosp, Dept Neurol & Neurorehabil, Ist Auxol Italiano IRCCS, Verbania, Italy.

Mauro, Alessandro (författare): Univ Turin, Dept Neurosci Rita Levi Montalcini, Turin, Italy.;San Giuseppe Hosp, Dept Neurol & Neurorehabil, Ist Auxol Italiano IRCCS, Verbania, Italy.

Riva, Giuseppe (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;Catholic Univ Milan, Dept Psychol, Milan, Italy.

Di Lernia, Daniele (författare): Catholic Univ Milan, Dept Psychol, Milan, Italy.

Repetto, Claudia (författare): Catholic Univ Milan, Dept Psychol, Milan, Italy.

Regalia, Camillo (författare): Catholic Univ Milan, Dept Psychol, Milan, Italy.

Molinari, Enrico (författare): San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;Catholic Univ Milan, Dept Psychol, Milan, Italy.

Notaro, Paolo (författare): AO Osped Niguarda Ca Granda, Anesthesiol Dept, Pain Med, Milan, Italy.

Paolucci, Stefano (författare): Fdn Santa Lucia IRCCS, Rome, Italy.

Sandrini, Giorgio (författare): C Mondino Natl Neurol Inst, Pavia, Italy.;Univ Pavia, Dept Brain & Behav Sci, Pavia, Italy.

Simpson, Susan (författare): Univ South Australia, Adelaide, SA, Australia.;NHS Lothian, Reg Eating Disorders Unit, Livingston, Scotland.

Wiederhold, Brenda Kay (författare): Virtual Real Med Inst, Brussels, Belgium.

Gaudio, Santino (författare): Uppsala universitet,Funktionell farmakologi

Jackson, Jeffrey B. (författare): Virginia Tech, Falls Church, VA USA.

Tamburin, Stefano (författare): Univ Verona, Dept Neurosci Biomed & Movement Sci, Verona, Italy.

Benedetti, Fabrizio (författare): Univ Turin, Dept Neurosci Rita Levi Montalcini, Turin, Italy.

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San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy;Catholic Univ Milan, Dept Psychol, Milan, Italy. San Giuseppe Hosp, Psychol Res Lab, Ist Auxol Italiano IRCCS, Verbania, Italy.;eCampus Univ, Fac Psychol, Novedrate, Italy. (creator_code:org_t)

2018-05-18
2018
Engelska.
Ingår i: Frontiers in Neurology. - : Frontiers Media SA. - 1664-2295. ; 9

Relaterad länk:: https://doi.org/10.3...; visa fler...; https://uu.diva-port... (primary) (Raw object); https://www.frontier...; https://urn.kb.se/re...; https://doi.org/10.3...; visa färre...

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Background: It is increasingly acknowledged that the outcomes of medical treatments are influenced by the context of the clinical encounter through the mechanisms of the placebo effect. The phenomenon of placebo analgesia might be exploited to maximize the efficacy of neurorehabilitation treatments. Since its intensity varies across neurological disorders, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCP) summarized the studies on this field to provide guidance on its use.Methods: A review of the existing reviews and meta-analyses was performed to assess the magnitude of the placebo effect in disorders that may undergo neurorehabilitation treatment. The search was performed on Pubmed using placebo, pain, and the names of neurological disorders as keywords. Methodological quality was assessed using a pre-existing checklist. Data about the magnitude of the placebo effect were extracted from the included reviews and were commented in a narrative form.Results: 11 articles were included in this review. Placebo treatments showed weak effects in central neuropathic pain (pain reduction from 0.44 to 0.66 on a 0-10 scale) and moderate effects in postherpetic neuralgia (1.16), in diabetic peripheral neuropathy (1.45), and in pain associated to HIV (1.82). Moderate effects were also found on pain due to fibromyalgia and migraine; only weak short-term effects were found in complex regional pain syndrome. Confounding variables might have influenced these results.Clinical implications: These estimates should be interpreted with caution, but underscore that the placebo effect can be exploited in neurorehabilitation programs. It is not necessary to conceal its use from the patient. Knowledge of placebo mechanisms can be used to shape the doctor-patient relationship, to reduce the use of analgesic drugs and to train the patient to become an active agent of the therapy.

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Av författaren/redakt...: Castelnuovo, Gia ...; Giusti, Emanuele ...; Manzoni, Gian Ma ...; Saviola, Donatel ...; Gabrielli, Saman ...; Lacerenza, Marco; visa fler...; Pietrabissa, Gia ...; Cattivelli, Robe ...; Spatola, Chiara ...; Rossi, Alessandr ...; Varallo, Giorgia; Novelli, Margher ...; Villa, Valentina; Luzzati, Frances ...; Cottini, Andrea; Lai, Carlo; Volpato, Eleonor ...; Cavalera, Cesare; Pagnini, Frances ...; Tesio, Valentina; Castelli, Lorys; Tavola, Mario; Torta, Riccardo; Arreghini, Marco; Zanini, Loredana; Brunani, Amelia; Seitanidis, Iona ...; Ventura, Giusepp ...; Capodaglio, Paol ...; D'Aniello, Guido ...; Scarpina, Federi ...; Brioschi, Andrea; Bigoni, Matteo; Priano, Lorenzo; Mauro, Alessandr ...; Riva, Giuseppe; Di Lernia, Danie ...; Repetto, Claudia; Regalia, Camillo; Molinari, Enrico; Notaro, Paolo; Paolucci, Stefan ...; Sandrini, Giorgi ...; Simpson, Susan; Wiederhold, Bren ...; Gaudio, Santino; Jackson, Jeffrey ...; Tamburin, Stefan ...; Benedetti, Fabri ...; visa färre...

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What Is the Role of the Placebo Effect for Pain Relief in Neurorehabilitation? : Clinical Implications From the Italian Consensus Conference on Pain in Neurorehabilitation

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