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Unilateral Extrapul...
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Moore, Alastair J.Department of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(författare)
Unilateral Extrapulmonary Airway Bypass in Advanced Emphysema
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
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Elsevier BV,2010
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:kth-19235
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https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-19235URI
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https://doi.org/10.1016/j.athoracsur.2009.10.067DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-158URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:120046202URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:rkh:diva-488URI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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QC 20110210
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Background. Gas trapping in emphysema results in resting and dynamic hyperinflation. We tested the hypothesis that a direct connection between the lung parenchyma and the atmosphere could increase expiratory flow and thereby potentially improve dyspnea through the relief of gas trapping. Methods. Ex vivo we studied 7 emphysematous lungs and 3 fibrotic lungs (as controls) and measured expiratory flow before and after airway bypass insertion during a forced maneuver in an artificial thorax. Pilot studies were conducted in vivo in 6 patients with advanced emphysema using a size 9 endotracheal tube as a bypass surgically placed through the chest wall into the upper lobe. Results. In the ex vivo emphysematous lungs the volume expelled during a forced expiratory maneuver increased from 169 to 235 mL (p < 0.05). In the in vivo group 4 patients retained the bypass tube for 3 months or more; total lung capacity was reduced, and the forced expiratory volume in 1 second increased by 23% (mean percent predicted at baseline versus 3 months, 24.4% versus 29.5%). Conclusions. An extrapulmonary airway bypass increases expiratory flow in emphysema. This may be a useful approach in hyperinflated patients with homogeneous emphysema. (Ann Thorac Surg 2010;89:899-906)
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Cetti, EdwardDepartment of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(författare)
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Haj-Yahia, SaleemDepartment of Thoracic Surgery, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(författare)
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Carby, MartinDepartment of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(författare)
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Björling, Gunilla,DocentKarolinska Institutet,Sophiahemmet Högskola,Division of Anaesthesia and Intensive Care, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm(Swepub:rkh)bjog
(författare)
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Karlsson, SigbrittKTH,Fiber- och polymerteknologi,Fibre and Polymer Technology, School of Chemical Science and Engineering, Royal Institute of Technology, Stockholm(Swepub:kth)u1g9umtq
(författare)
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Shah, PallavDepartment of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(författare)
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Goldstraw, PeterDepartment of Thoracic Surgery, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(författare)
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Moxham, JohnDepartment of Respiratory Medicine, Kings College Hospital, London, United Kingdom
(författare)
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Jordan, SimonDepartment of Thoracic Surgery, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(författare)
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Polkey, Michael I.Department of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(författare)
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Department of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, United KingdomDepartment of Thoracic Surgery, Royal Brompton and Harefield NHS Trust, London, United Kingdom
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Annals of Thoracic Surgery: Elsevier BV89:3, s. 899-906E20003-49751552-6259
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Till lärosätets databas
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Moore, Alastair ...
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Cetti, Edward
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Haj-Yahia, Salee ...
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Carby, Martin
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Björling, Gunill ...
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Karlsson, Sigbri ...
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visa fler...
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Shah, Pallav
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Goldstraw, Peter
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Moxham, John
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Jordan, Simon
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Polkey, Michael ...
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visa färre...
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Kungliga Tekniska Högskolan
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Sophiahemmet Högskola
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Karolinska Institutet
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Röda Korsets Högskola