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Sökning: onr:"swepub:oai:DiVA.org:lnu-58082" > The association bet...

  • Borghi, ClaudioUniversity of Bologna, Italy (författare)

The association between blood pressure and lipid levels in Europe : European study on cardiovascular risk prevention and management in usual daily practice

  • Artikel/kapitelEngelska2016

Förlag, utgivningsår, omfång ...

  • 2016
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:lnu-58082
  • https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-58082URI
  • https://doi.org/10.1097/HJH.0000000000001078DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Objectives:Several studies have suggested a positive association between serum lipid levels and blood pressure (BP). This study investigated this association in a large population from 12 European countries.Methods:Data were taken from the European Study on Cardiovascular Risk Prevention and Management in Usual Daily Practice (ClinicalTrials.gov identifier: NCT00882336). Associations between BP and lipid levels in patients free from cardiovascular disease and with at least one major cardiovascular disease risk factor (N=7641) were assessed using linear regression analyses.Results:Overall, 72.8 and 64.8% of patients had hypertension and dyslipidaemia, respectively; 47.0% had both conditions. Regression coefficients (95% confidence interval) for the associations of LDL cholesterol, non-HDL cholesterol, total cholesterol and apolipoprotein B levels with SBP, adjusted for age, sex and BMI, were 0.93mmHg/mmol per l (0.54-1.31), 1.07mmHg/mmol per l (0.73-1.40), 1.02mmHg/mmol per l (0.69-1.35) and 4.94mmHg/g per l (3.43-6.46), respectively. The corresponding values (95% confidence interval) for the associations with DBP were 0.96mmHg/mmol per l (0.73-1.19), 0.95mmHg/mmol per l (0.75-1.15), 0.87mmHg/mmol per l (0.67-1.07) and 4.33mmHg/g per l (3.42-5.23), respectively. Most of these associations remained significant whether patients were treated with statins or not.Conclusion:Small but statistically significant associations between lipid levels and BP were observed in a large, multinational European population. Further research is warranted to assess the causality of this association and its implications on the management of patients with both hypertension and dyslipidaemia.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Rodriguez-Artalejo, FernandoUniv Autonoma Madrid IdiPaz, Spain ; Inst Salud Carlos III, Spain (författare)
  • De Backer, GuyUniv Ghent, Belgium (författare)
  • Dallongeville, JeanUniv Lille Nord France, France (författare)
  • Medina, JesúsAstraZeneca Farmaceut Spain, Spain (författare)
  • Guallar, EliseoJohns Hopkins Bloomberg Sch Publ Hlth, USA ; Johns Hopkins Bloomberg Sch Publ Hlth, USA (författare)
  • Perk, JoepLinnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV)(Swepub:lnu)jpejo (författare)
  • Banegas, José R.Univ Autonoma Madrid IdiPaz, Spain ; Inst Salud Carlos III, Spain (författare)
  • Tubach, FlorenceHop Bichat Claude Bernard, France ; ECEVE, France ; Univ Paris Diderot, France (författare)
  • Roy, CarineHop Bichat Claude Bernard, France ; ECEVE, France ; Hop Bichat Claude Bernard, France (författare)
  • Halcox, Julian P.Swansea Univ, UK (författare)
  • University of Bologna, ItalyUniv Autonoma Madrid IdiPaz, Spain ; Inst Salud Carlos III, Spain (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Journal of Hypertension34:11, s. 2155-21630263-63521473-5598

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