International renal-cell cancer study. IV. Occupation

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Mandel, J. S.School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States (författare)

The relationship between renal-cell cancer (RCC) and occupation was investigated in an international multicenter population-based case-control study. Study centers in Australia, Denmark, Germany, Sweden and the United States interviewed 1732 incident RCC cases and 2309 controls. Significant associations were found with employment in the blast-furnace or the coke-oven industry [relative risk (RR), 1.7; 95% confidence interval (CI), 1.1-2.7], the iron and steel industry (RR, 1.6; 95% CI, 1.2-2.2) and exposure to asbestos (RR, 1.4; 95% CI, 1.1-1.8), cadmium (RR, 2.0; 95% CI, 1.0-3.9), dry-cleaning solvents (RR, 1.4; 95% CI, 1.1-1.7), gasoline (RR, 1.6; 95% CI, 1.2-2.0) and other petroleum products (RR, 1.6; 95% CI, 1.3-2.1). Asbestos, petroleum products and dry-cleaning solvents appear to merit further investigation, in view of the relationship between risk and duration of employment or exposure and after adjustment for confounding. There was a negative association between RCC and education, but it was not consistent across all centers. Overall, the results of our multicenter case-control study suggest that occupation may be more important in the etiology of RCC than indicated by earlier studies.

McLaughlin, J. K.National Cancer Institute, Division of Cancer Etiology, Bethesda, Maryland, United States (författare)
Schlehofer, B.German Cancer Research Center, Division of Epidemiology, Heidelberg, Germany (författare)
Mellemgaard, A.Danish Cancer Society, Copenhagen, Denmark (författare)
Helmert, U.Bremer Institute for Prevention and Social Medicine, Bremen, Germany (författare)
Lindblad, Per,1953-Department of Cancer Epidemiology, University Hospital, Uppsala, Sweden(Swepub:oru)pld (författare)
McCredie, M.Cancer Epidemiology Research Unit, New South Wales Cancer Council, Sydney, Australia (författare)
Adami, H. O.Uppsala University, Uppsala, Sweden (författare)
School of Public Health, University of Minnesota, Minneapolis, Minnesota, United StatesNational Cancer Institute, Division of Cancer Etiology, Bethesda, Maryland, United States (creator_code:org_t)

Ingår i:International Journal of CancerNew York, USA : John Wiley & Sons61:5, s. 601-6050020-71361097-0215

Av författaren/redakt...: Mandel, J. S.; McLaughlin, J. K ...; Schlehofer, B.; Mellemgaard, A.; Helmert, U.; Lindblad, Per, 1 ...; visa fler...; McCredie, M.; Adami, H. O.; visa färre...

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