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Sökning: onr:"swepub:oai:lup.lub.lu.se:2acbaebe-3dd1-4d35-9230-faed992e8170" > Research Priorities...

  • Mathioudakis, Alexander G.University of Manchester,Wythenshawe Hospital (författare)

Research Priorities in Pediatric Asthma : Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank

  • Artikel/kapitelEngelska2020

Förlag, utgivningsår, omfång ...

  • Elsevier BV,2020

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:2acbaebe-3dd1-4d35-9230-faed992e8170
  • https://lup.lub.lu.se/record/2acbaebe-3dd1-4d35-9230-faed992e8170URI
  • https://doi.org/10.1016/j.jaip.2020.01.059DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:144535654URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Background: Pediatric asthma remains a public health challenge with enormous impact worldwide. Objective: The aim of this study was to identify and prioritize unmet clinical needs in pediatric asthma, which could be used to guide future research and policy activities. Methods: We first identified unmet needs through an open-question survey administered to international experts in pediatric asthma who were members of the Pediatric Asthma in Real Life Think Tank. Prioritization of topics was then achieved through a second, extensive survey with global reach, of multiple stakeholders (leading experts, researchers, clinicians, patients, policy makers, and the pharmaceutical industry). Differences across responder groups were compared. Results: A total of 57 unmet clinical need topics identified by international experts were prioritized by 412 participants from 5 continents and 60 countries. Prevention of disease progression and prediction of future risk, including persistence into adulthood, emerged as the most urgent research questions. Stratified care, based on biomarkers, clinical phenotypes, the children's age, and demographics were also highly rated. The identification of minimum diagnostic criteria in different age groups, cultural perceptions of asthma, and best treatment by age group were priorities for responders from low-middle-income countries. There was good agreement across different stakeholder groups in all domains with some notable exceptions that highlight the importance of involving the whole range of stakeholders in formulation of recommendations. Conclusions: Different stakeholders agree in the majority of research and strategic (eg, prevention, personalized approach) priorities for pediatric asthma. Stakeholder diversity is crucial for highlighting divergent issues that future guidelines should consider.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Custovic, AdnanImperial College London (författare)
  • Deschildre, AntoineUniversity of Lille,Lille University Hospital (författare)
  • Ducharme, Francine M.University Of Quebec In Montreal (författare)
  • Kalayci, OmerHacettepe University (författare)
  • Murray, ClareWythenshawe Hospital,University of Manchester (författare)
  • Garcia, Antonio NietoUniversity and Polytechnic Hospital la Fe (författare)
  • Phipatanakul, WandaBoston Children's Hospital (författare)
  • Price, DavidObservational and Pragmatic Research Institute Pte Ltd,University of Aberdeen (författare)
  • Sheikh, AzizUniversity of Edinburgh (författare)
  • Agache, IoanaTransylvania University Brasov (författare)
  • Bacharier, LeonardWashington University in St. Louis (författare)
  • Bonini, MatteoCatholic University of the Sacred Heart, Rome,Policlinico Universitario Agostino Gemelli,Imperial College London (författare)
  • Castro-Rodriguez, Jose A.Pontifical Catholic University of Chile (författare)
  • De Carlo, GiuseppeEFA European Federation of Allergy and Airways Diseases Patients' Associations (författare)
  • Craig, TimothyPennsylvania State University (författare)
  • Diamant, ZuzanaLund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,University Medical Center Groningen,Thomayer Hospital,Charles University in Prague,University of Groningen,Skåne University Hospital(Swepub:lu)med-zdt (författare)
  • Feleszko, WojciechChildren's Hospital of Medical University of Warsaw (författare)
  • Ierodiakonou, DespoUniversity of Crete (författare)
  • Gern, James E.University of Wisconsin-Madison (författare)
  • Grigg, JonathanQueen Mary University (författare)
  • Hedlin, GunillaKarolinska Institutet,Karolinska Institute (författare)
  • Hossny, Elham M.Children's Hospital of Ain Shams University (författare)
  • Jartti, TuomasTurku University Hospital,University of Turku (författare)
  • Kaplan, AlanUniversity of Toronto (författare)
  • Lemanske, Robert F.University of Wisconsin-Madison (författare)
  • Le Souef, PeterUniversity of Western Australia, Crawley (författare)
  • Makela, Mika J.University of Helsinki,Skin and Allergy Hospital (författare)
  • Matricardi, Paolo M.Charité - University Medicine Berlin (författare)
  • Miligkos, MichaelNational and Kapodistrian University of Athens,Aghia Sophia Children's Hospital (författare)
  • Morais-Almeida, MárioHospital CUF-Descobertas (författare)
  • Pite, HelenaNOVA University Lisbon,CUF Infante Santo Hospital,Hospital CUF-Descobertas (författare)
  • Pitrez, Paulo M.C.Pontifical Catholic University of Rio Grande do Sul (författare)
  • Pohunek, PetrUniversity Hospital Motol,Charles University in Prague (författare)
  • Roberts, GrahamUniversity Hospital Southampton,University of Southampton,St Mary's Hospital, Newport (författare)
  • Sanchez-Garcia, SylviaHospital Infantil Universitario Niño Jesús (författare)
  • Tsiligianni, IoannaUniversity of Crete (författare)
  • Turner, SteveUniversity of Aberdeen,Royal Aberdeen Children's Hospital (författare)
  • Winders, Tonya A.Global Allergy and Asthma Platform (GAAPP),Allergy & Asthma Network (författare)
  • Wong, GaryChinese University of Hong Kong (författare)
  • Xepapadaki, ParaskeviNational and Kapodistrian University of Athens (författare)
  • Zar, Heather J.University of Cape Town,Red Cross War Memorial Children’s Hospital, Cape Town (författare)
  • Papadopoulos, Nikolaos G.University of Manchester,National and Kapodistrian University of Athens (författare)
  • University of ManchesterWythenshawe Hospital (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Journal of Allergy and Clinical Immunology: In Practice: Elsevier BV8:6, s. 9-19602213-21982213-2201

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