Search: onr:"swepub:oai:lup.lub.lu.se:e035bef8-4504-4724-99cd-fe5d35bec984" >
The CCND1 c.870G > ...
The CCND1 c.870G > A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma
- Article/chapterEnglish2013
Publisher, publication year, extent ...
-
2013-03-17
-
Springer Science and Business Media LLC,2013
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:e035bef8-4504-4724-99cd-fe5d35bec984
-
https://lup.lub.lu.se/record/3843820URI
-
https://doi.org/10.1038/ng.2583DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:art swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
A number of specific chromosomal abnormalities define the subgroups of multiple myeloma. In a meta-analysis of two genome-wide association studies of multiple myeloma including a total of 1,661 affected individuals, we investigated risk for developing a specific tumor karyotype. The t(11;14)(q13;q32) translocation in which CCND1 is placed under the control of the immunoglobulin heavy chain enhancer was strongly associated with the CCND1 c.870G>A polymorphism (P = 7.96 x 10(-11)). These results provide a model in which a constitutive genetic factor is associated with risk of a specific chromosomal translocation.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Johnson, David C.
(author)
-
Chubb, Daniel
(author)
-
Chen, Bowang
(author)
-
Försti, AstaLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups(Swepub:lu)med-asf
(author)
-
Hosking, Fay J.
(author)
-
Broderick, Peter
(author)
-
Ma, Yussanne P.
(author)
-
Dobbins, Sara E.
(author)
-
Hose, Dirk
(author)
-
Walker, Brian A.
(author)
-
Davies, Faith E.
(author)
-
Kaiser, Martin F.
(author)
-
Li, Ni L.
(author)
-
Gregory, Walter A.
(author)
-
Jackson, Graham H.
(author)
-
Witzens-Harig, Mathias
(author)
-
Neben, Kai
(author)
-
Hoffmann, Per
(author)
-
Noethen, Markus M.
(author)
-
Muehleisen, Thomas W.
(author)
-
Eisele, Lewin
(author)
-
Ross, Fiona M.
(author)
-
Jauch, Anna
(author)
-
Goldschmidt, Hartmut
(author)
-
Houlston, Richard S.
(author)
-
Morgan, Gareth J.
(author)
-
Hemminki, KariLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups(Swepub:lu)med-khk
(author)
-
Allmänmedicin och klinisk epidemiologiForskargrupper vid Lunds universitet
(creator_code:org_t)
Related titles
-
In:Nature Genetics: Springer Science and Business Media LLC45:5, s. 522-5251546-17181061-4036
Internet link
Find in a library
To the university's database
- By the author/editor
-
Weinhold, Niels
-
Johnson, David C ...
-
Chubb, Daniel
-
Chen, Bowang
-
Försti, Asta
-
Hosking, Fay J.
-
show more...
-
Broderick, Peter
-
Ma, Yussanne P.
-
Dobbins, Sara E.
-
Hose, Dirk
-
Walker, Brian A.
-
Davies, Faith E.
-
Kaiser, Martin F ...
-
Li, Ni L.
-
Gregory, Walter ...
-
Jackson, Graham ...
-
Witzens-Harig, M ...
-
Neben, Kai
-
Hoffmann, Per
-
Noethen, Markus ...
-
Muehleisen, Thom ...
-
Eisele, Lewin
-
Ross, Fiona M.
-
Jauch, Anna
-
Goldschmidt, Har ...
-
Houlston, Richar ...
-
Morgan, Gareth J ...
-
Hemminki, Kari
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Public Health Gl ...
- Articles in the publication
-
Nature Genetics
- By the university
-
Lund University