Expanding roles of RNA-binding proteins in neurodegenerative diseases / Aaron D. Gitler.

• Contents: Amyotrophic lateral sclerosis (ALS) -- Genetic causes of ALS -- Role of RNA-binding proteins and stress granules in ALS pathogenesis -- Emerging class of RNA-binding proteins with prion-like domains in neurodegenerative disease -- Mechanisms by which C9ORF72 mutations cause ALS.

Ämnesord

Amyotrophic lateral sclerosis.  (LCSH)

Prions.  (LCSH)

RNA-protein interactions.  (LCSH)

Nervous system  -- Degeneration -- Genetic aspects. (LCSH)

Nervous system  -- Diseases -- Genetic aspects. (LCSH)

Ataxins.  (MeSH)

Genetic Predisposition to Disease.  (MeSH)

Amyotrophic Lateral Sclerosis  -- genetics. (MeSH)

Nerve Tissue Proteins  -- genetics. (MeSH)

Neurodegenerative Diseases  -- genetics. (MeSH)

Prions  -- genetics. (MeSH)

RNA-Binding Proteins  -- genetics. (MeSH)

RNA-Binding Proteins  -- physiology. (MeSH)