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SPE and HPLC/UV of ...
SPE and HPLC/UV of resin acids in colophonium-containing products.
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- Nilsson, Ulrika Nilsson (författare)
- Stockholms universitet,Institutionen för analytisk kemi
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- Berglund, Naghmeh (författare)
- Stockholms universitet,Institutionen för analytisk kemi
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- Lindahl, Fredrik (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi,Department of Chemistry
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- Axelsson, Sara (författare)
- Stockholms universitet,Örebro universitet,Hälsoakademin,Institutionen för analytisk kemi
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- Redeby, Theres, 1973 (författare)
- Stockholms universitet,Gothenburg University,Göteborgs universitet,Institutionen för kemi,Department of Chemistry,Institutionen för analytisk kemi
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- Lassen, Pia (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi,Department of Chemistry
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- Karlberg, Ann-Therese, 1947 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi,Department of Chemistry
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(creator_code:org_t)
- Weinheim, Fed. Rep. of Germany : Wiley, 2008
- 2008
- Engelska.
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Ingår i: Journal of separation science. - Weinheim, Fed. Rep. of Germany : Wiley. - 1615-9314 .- 1615-9306. ; 31:15, s. 2784-90
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- A new method, involving SPE and HPLC/UV diode-array detection (DAD), was developed for the quantification of colophonium components in different consumer products, such as cosmetics. Colophonium is a common cause of contact dermatitis since its components can oxidize into allergens on exposure to air. Three different resin acids were used as markers for native and oxidized colophonium, abietic acid (AbA), dehydroabietic acid (DeA), and 7-oxodehydroabietic acid (7-O-DeA). The SPE method, utilizing a mixed-mode hydrophobic and anion exchange retention mechanism, was shown to yield very clean extracts. The use of a urea-embedded C(12) HPLC stationary phase improved the separation of the resin acids compared to common C(18). Concentrations higher than 2 mg/g of both AbA and DeA were detected in wax strips. In this product also 7-O-DeA, a marker for oxidized colophonium, was detected at a level of 28 microg/g. The LODs were in the range of 7-19 microg/g and the LOQs 22-56 microg/g. The method is simple to use and can be applied on many types of technical products, not only cosmetics. For the first time, a method for technical products was developed, which separates AbA from pimaric acid.
Ämnesord
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- NATURVETENSKAP -- Kemi -- Analytisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Analytical Chemistry (hsv//eng)
Nyckelord
- Abscisic Acid
- analysis
- Chromatography
- High Pressure Liquid
- instrumentation
- methods
- Diterpenes
- Abietane
- analysis
- chemical synthesis
- Ethanolamines
- analysis
- Molecular Conformation
- Resins
- Plant
- analysis
- chemistry
- Sensitivity and Specificity
- Solid Phase Extraction
- instrumentation
- methods
- Spectrophotometry
- Ultraviolet
- instrumentation
- methods
- Stereoisomerism
- MEDICINE
- Occupational medicine
- Occupational and Environmental Medicine
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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