onr:"20183843"
Sökning: onr:"20183843" > The draft genome se...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04054naa a22008773a 4500 | |
| 001 | 20183843 | |
| 003 | SE-LIBR | |
| 005 | 20170322143407.0 | |
| 007 | cr|||||||||||| | |
| 008 | 170322s2014 sw |||| o |||| ||eng c | |
| 024 | 7 | a http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2414272 uri |
| 024 | 7 | a urn:nbn:se:uu:diva-2414272 urn |
| 024 | 7 | a 10.1038/nbt.30792 doi |
| 040 | a S | |
| 041 | 0 | a eng |
| 042 | 9 EPLK | |
| 100 | 1 | a Peng, Xinxia4 aut |
| 245 | 1 0 | a The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory diseaseh [Elektronisk resurs] |
| 260 | c 2014 | |
| 500 | a Published | |
| 506 | 0 | a gratis |
| 520 | a The domestic ferret (Mustela putorius furo) is an important animal model for multiple human respiratory diseases. It is considered the 'gold standard' for modeling human influenza virus infection and transmission(1-)4. Here we describe the 2.41 Gb draft genome assembly of the domestic ferret, constituting 2.28 Gb of sequence plus gaps. We annotated 19,910 protein-coding genes on this assembly using RNA-seq data from 21 ferret tissues. We characterized the ferret host response to two influenza virus infections by RNA-seq analysis of 42 ferret samples from influenza time-course data and showed distinct signatures in ferret trachea and lung tissues specific to 1918 or 2009 human pandemic influenza virus infections. Using microarray data from 16 ferret samples reflecting cystic fibrosis disease progression, we showed that transcriptional changes in the CFTR-knockout ferret lung reflect pathways of early disease that cannot be readily studied in human infants with cystic fibrosis disease. | |
| 650 | 7 | a Medical and Health Sciences2 hsv |
| 650 | 7 | a Basic Medicine2 hsv |
| 650 | 7 | a Microbiology in the medical area2 hsv |
| 650 | 7 | a Medicin och hälsovetenskap2 hsv |
| 650 | 7 | a Medicinska grundvetenskaper2 hsv |
| 650 | 7 | a Mikrobiologi inom det medicinska området2 hsv |
| 700 | 1 | a Alfoeldi, Jessica4 aut |
| 700 | 1 | a Gori, Kevin4 aut |
| 700 | 1 | a Eisfeld, Amie J.4 aut |
| 700 | 1 | a Tyler, Scott R.4 aut |
| 700 | 1 | a Tisoncik-Go, Jennifer4 aut |
| 700 | 1 | a Brawand, David4 aut |
| 700 | 1 | a Law, G. Lynn4 aut |
| 700 | 1 | a Skunca, Nives4 aut |
| 700 | 1 | a Hatta, Masato4 aut |
| 700 | 1 | a Gasper, David J.4 aut |
| 700 | 1 | a Kelly, Sara M.4 aut |
| 700 | 1 | a Chang, Jean4 aut |
| 700 | 1 | a Thomas, Matthew J.4 aut |
| 700 | 1 | a Johnson, Jeremy4 aut |
| 700 | 1 | a Berlin, Aaron M.4 aut |
| 700 | 1 | a Lara, Marcia4 aut |
| 700 | 1 | a Russell, Pamela4 aut |
| 700 | 1 | a Swofford, Ross4 aut |
| 700 | 1 | a Turner-Maier, Jason4 aut |
| 700 | 1 | a Young, Sarah4 aut |
| 700 | 1 | a Hourlier, Thibaut4 aut |
| 700 | 1 | a Aken, Bronwen4 aut |
| 700 | 1 | a Searle, Steve4 aut |
| 700 | 1 | a Sun, Xingshen4 aut |
| 700 | 1 | a Yi, Yaling4 aut |
| 700 | 1 | a Suresh, M.4 aut |
| 700 | 1 | a Tumpey, Terrence M.4 aut |
| 700 | 1 | a Siepel, Adam4 aut |
| 700 | 1 | a Wisely, Samantha M.4 aut |
| 700 | 1 | a Dessimoz, Christophe4 aut |
| 700 | 1 | a Kawaoka, Yoshihiro4 aut |
| 700 | 1 | a Birren, Bruce W.4 aut |
| 700 | 1 | a Lindblad-Toh, Kerstin4 aut0 268427 |
| 700 | 1 | a Di Palma, Federica4 aut |
| 700 | 1 | a Engelhardt, John F.4 aut |
| 700 | 1 | a Palermo, Robert E.4 aut |
| 700 | 1 | a Katze, Michael G.4 aut |
| 710 | 1 2 | a Uppsala universitetb Medicinska och farmaceutiska vetenskapsområdet4 pbl |
| 772 | 1 8 | i channel recordw 19753896 |
| 773 | 0 8 | i Värdpublikationt Nature Biotechnologyg 32:12, 1250-U114x 1087-0156 |
| 856 | 4 0 | u http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-241427 |
| 856 | 4 0 | u http://dx.doi.org/10.1038/nbt.3079 |
| 856 | 4 0 | u http://uu.diva-portal.org/smash/get/diva2:781502/FULLTEXT01 |
| 900 | 1 s | 6 700a Toh, Kerstin Lindblad-u Lindblad-Toh, Kerstin |
| 841 | 5 APISa x ab 170322||0000|||||001||||||000000e 1 | |
| 024 | 7 | 5 APISa urn:nbn:se:uu:diva-2414272 urn |
| 852 | 5 APISb APIS | |
| 856 | 4 0 | 5 APISu http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-241427 |
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