Sökning: onr:"22087198" > Consumption of Dair...
Fältnamn | Indikatorer | Metadata |
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000 | 05589naa a22009973a 4500 | |
001 | 22087198 | |
003 | SE-LIBR | |
005 | 20171207202721.0 | |
007 | cr|||||||||||| | |
008 | 171207s2013 sw |||| o |||| ||eng c | |
024 | 7 | a http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-815122 uri |
024 | 7 | a urn:nbn:se:umu:diva-815122 urn |
024 | 7 | a 10.1371/journal.pone.00727152 doi |
040 | a S | |
041 | 0 | a eng |
042 | 9 EPLK | |
100 | 1 | a Murphy, Neil4 aut |
245 | 1 0 | a Consumption of Dairy Products and Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)h [Elektronisk resurs] |
260 | c 2013 | |
500 | a Published | |
506 | 0 | a gratis |
520 | a Background: Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of total dairy products, total milk and dietary calcium. However, less is known about whether the inverse associations vary for individual dairy products with differing fat contents. Materials and Methods: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we investigated the associations between intakes of total milk and milk subtypes (whole-fat, semi-skimmed and skimmed), yoghurt, cheese, and dietary calcium with colorectal cancer risk amongst 477,122 men and women. Dietary questionnaires were administered at baseline. Multivariable hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models, adjusted for relevant confounding variables. Results: During the mean 11 years of follow-up, 4,513 incident cases of colorectal cancer occurred. After multivariable adjustments, total milk consumption was inversely associated with colorectal cancer risk (HR per 200 g/day 0.93, 95% CI: 0.89-0.98). Similar inverse associations were observed for whole-fat (HR per 200 g/day 0.90, 95% CI: 0.82-0.99) and skimmed milk (HR per 200 g/day 0.90, 95% CI: 0.79-1.02) in the multivariable models. Inverse associations were observed for cheese and yoghurt in the categorical models; although in the linear models, these associations were non-significant. Dietary calcium was inversely associated with colorectal cancer risk (HR per 200 mg/day 0.95, 95% CI: 0.91-0.99); this association was limited to dairy sources of calcium only (HR per 200 mg/day 0.95, 95% CI: 0.91-0.99), with no association observed for non-dairy calcium sources (HR per 200 mg/day 1.00, 95% CI: 0.81-1.24). Conclusions: Our results strengthen the evidence for a possible protective role of dairy products on colorectal cancer risk. The inverse associations we observed did not differ by the fat content of the dairy products considered. | |
650 | 7 | a Medical and Health Sciences2 hsv |
650 | 7 | a Clinical Medicine2 hsv |
650 | 7 | a Cancer and Oncology2 hsv |
650 | 7 | a Medicin och hälsovetenskap2 hsv |
650 | 7 | a Klinisk medicin2 hsv |
650 | 7 | a Cancer och onkologi2 hsv |
700 | 1 | a Norat, Teresa4 aut |
700 | 1 | a Ferrari, Pietro4 aut |
700 | 1 | a Jenab, Mazda4 aut |
700 | 1 | a Bueno-de-Mesquita, Bas4 aut |
700 | 1 | a Skeie, Guri4 aut |
700 | 1 | a Olsen, Anja4 aut |
700 | 1 | a Tjonneland, Anne4 aut |
700 | 1 | a Dahm, Christina C.4 aut |
700 | 1 | a Overvad, Kim4 aut |
700 | 1 | a Boutron-Ruault, Marie Christine4 aut |
700 | 1 | a Clavel-Chapelon, Francoise4 aut |
700 | 1 | a Nailler, Laura4 aut |
700 | 1 | a Kaaks, Rudolf4 aut |
700 | 1 | a Teucher, Birgit4 aut |
700 | 1 | a Boeing, Heiner4 aut |
700 | 1 | a Bergmann, Manuela M.4 aut |
700 | 1 | a Trichopoulou, Antonia4 aut |
700 | 1 | a Lagiou, Pagona4 aut |
700 | 1 | a Trichopoulos, Dimitrios4 aut |
700 | 1 | a Palli, Domenico4 aut |
700 | 1 | a Pala, Valeria4 aut |
700 | 1 | a Tumino, Rosario4 aut |
700 | 1 | a Vineis, Paolo4 aut |
700 | 1 | a Panico, Salvatore4 aut |
700 | 1 | a Peeters, Petra H. M.4 aut |
700 | 1 | a Dik, Vincent K.4 aut |
700 | 1 | a Weiderpass, Elisabete4 aut |
700 | 1 | a Lund, Eiliv4 aut |
700 | 1 | a Quiros Garcia, Jose Ramon4 aut |
700 | 1 | a Zamora-Ros, Raul4 aut |
700 | 1 | a Sanchez Perez, Maria Jose4 aut |
700 | 1 | a Dorronsoro, Miren4 aut |
700 | 1 | a Navarro, Carmen4 aut |
700 | 1 | a Ardanaz, Eva4 aut |
700 | 1 | a Manjer, Jonas4 aut |
700 | 1 | a Almquist, Martin4 aut |
700 | 1 | a Johansson, Ingegerd4 aut |
700 | 1 | a Palmqvist, Richard4 aut |
700 | 1 | a Khaw, Kay-Tee4 aut |
700 | 1 | a Wareham, Nick4 aut |
700 | 1 | a Key, Timothy J.4 aut |
700 | 1 | a Crowe, Francesca L.4 aut |
700 | 1 | a Fedirko, Veronika4 aut |
700 | 1 | a Gunter, Marc J.4 aut |
700 | 1 | a Riboli, Elio4 aut |
710 | 1 2 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
710 | 1 2 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
772 | 1 8 | i channel recordw 18813935 |
773 | 0 8 | i Värdpublikationt PLoS ONEg 8:9, e72715x 1932-6203 |
856 | 4 0 | u http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81512 |
856 | 4 0 | u http://dx.doi.org/10.1371/journal.pone.0072715 |
856 | 4 0 | u http://umu.diva-portal.org/smash/get/diva2:657044/FULLTEXT01 |
910 | 2 s | 6 710,710a Umeå universitet.b Medicinsk-odontologiska fakultetenu Umeå universitet.b Medicinska fakulteten |
910 | 2 s | 6 710,710a Medicinska fakulteten vid Umeå universitetu Umeå universitet.b Medicinska fakulteten |
841 | 5 APISa x ab 171207||0000|||||001||||||000000e 1 | |
024 | 7 | 5 APISa urn:nbn:se:umu:diva-815122 urn |
852 | 5 APISb APIS | |
856 | 4 0 | 5 APISu http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81512 |
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