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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005589naa a22009973a 4500
00122087198
003SE-LIBR
00520171207202721.0
007cr||||||||||||
008171207s2013 sw |||| o |||| ||eng c
024a http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-815122 uri
024a urn:nbn:se:umu:diva-815122 urn
024a 10.1371/journal.pone.00727152 doi
040 a S
041a eng
042 9 EPLK
100a Murphy, Neil4 aut
2451 0a Consumption of Dairy Products and Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)h [Elektronisk resurs]
260 c 2013
500 a Published
506a gratis
520 a Background: Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of total dairy products, total milk and dietary calcium. However, less is known about whether the inverse associations vary for individual dairy products with differing fat contents. Materials and Methods: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we investigated the associations between intakes of total milk and milk subtypes (whole-fat, semi-skimmed and skimmed), yoghurt, cheese, and dietary calcium with colorectal cancer risk amongst 477,122 men and women. Dietary questionnaires were administered at baseline. Multivariable hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models, adjusted for relevant confounding variables. Results: During the mean 11 years of follow-up, 4,513 incident cases of colorectal cancer occurred. After multivariable adjustments, total milk consumption was inversely associated with colorectal cancer risk (HR per 200 g/day 0.93, 95% CI: 0.89-0.98). Similar inverse associations were observed for whole-fat (HR per 200 g/day 0.90, 95% CI: 0.82-0.99) and skimmed milk (HR per 200 g/day 0.90, 95% CI: 0.79-1.02) in the multivariable models. Inverse associations were observed for cheese and yoghurt in the categorical models; although in the linear models, these associations were non-significant. Dietary calcium was inversely associated with colorectal cancer risk (HR per 200 mg/day 0.95, 95% CI: 0.91-0.99); this association was limited to dairy sources of calcium only (HR per 200 mg/day 0.95, 95% CI: 0.91-0.99), with no association observed for non-dairy calcium sources (HR per 200 mg/day 1.00, 95% CI: 0.81-1.24). Conclusions: Our results strengthen the evidence for a possible protective role of dairy products on colorectal cancer risk. The inverse associations we observed did not differ by the fat content of the dairy products considered.
650 7a Medical and Health Sciences2 hsv
650 7a Clinical Medicine2 hsv
650 7a Cancer and Oncology2 hsv
650 7a Medicin och hälsovetenskap2 hsv
650 7a Klinisk medicin2 hsv
650 7a Cancer och onkologi2 hsv
700a Norat, Teresa4 aut
700a Ferrari, Pietro4 aut
700a Jenab, Mazda4 aut
700a Bueno-de-Mesquita, Bas4 aut
700a Skeie, Guri4 aut
700a Olsen, Anja4 aut
700a Tjonneland, Anne4 aut
700a Dahm, Christina C.4 aut
700a Overvad, Kim4 aut
700a Boutron-Ruault, Marie Christine4 aut
700a Clavel-Chapelon, Francoise4 aut
700a Nailler, Laura4 aut
700a Kaaks, Rudolf4 aut
700a Teucher, Birgit4 aut
700a Boeing, Heiner4 aut
700a Bergmann, Manuela M.4 aut
700a Trichopoulou, Antonia4 aut
700a Lagiou, Pagona4 aut
700a Trichopoulos, Dimitrios4 aut
700a Palli, Domenico4 aut
700a Pala, Valeria4 aut
700a Tumino, Rosario4 aut
700a Vineis, Paolo4 aut
700a Panico, Salvatore4 aut
700a Peeters, Petra H. M.4 aut
700a Dik, Vincent K.4 aut
700a Weiderpass, Elisabete4 aut
700a Lund, Eiliv4 aut
700a Quiros Garcia, Jose Ramon4 aut
700a Zamora-Ros, Raul4 aut
700a Sanchez Perez, Maria Jose4 aut
700a Dorronsoro, Miren4 aut
700a Navarro, Carmen4 aut
700a Ardanaz, Eva4 aut
700a Manjer, Jonas4 aut
700a Almquist, Martin4 aut
700a Johansson, Ingegerd4 aut
700a Palmqvist, Richard4 aut
700a Khaw, Kay-Tee4 aut
700a Wareham, Nick4 aut
700a Key, Timothy J.4 aut
700a Crowe, Francesca L.4 aut
700a Fedirko, Veronika4 aut
700a Gunter, Marc J.4 aut
700a Riboli, Elio4 aut
7101 2a Umeå universitetb Medicinska fakulteten4 pbl0 268483
7101 2a Umeå universitetb Medicinska fakulteten4 pbl0 268483
7721 8i channel recordw 18813935
7730 8i Värdpublikationt PLoS ONEg 8:9, e72715x 1932-6203
8564 0u http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81512
8564 0u http://dx.doi.org/10.1371/journal.pone.0072715
8564 0u http://umu.diva-portal.org/smash/get/diva2:657044/FULLTEXT01
9102 s6 710,710a Umeå universitet.b Medicinsk-odontologiska fakultetenu Umeå universitet.b Medicinska fakulteten
9102 s6 710,710a Medicinska fakulteten vid Umeå universitetu Umeå universitet.b Medicinska fakulteten
841 5 APISa x ab 171207||0000|||||001||||||000000e 1
0245 APISa urn:nbn:se:umu:diva-815122 urn
852 5 APISb APIS
8564 05 APISu http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81512

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