Sökning: onr:"swepub:oai:DiVA.org:umu-25443" > Genome-wide associa...
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000 | 04825naa a2201117 4500 | |
001 | oai:DiVA.org:umu-25443 | |
003 | SwePub | |
008 | 090818s2009 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-254432 URI |
024 | 7 | a https://doi.org/10.1038/ng.4292 DOI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Amundadottir, Laufey4 aut |
245 | 1 0 | a Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. |
264 | c 2009-08-02 | |
264 | 1 | b Springer Science and Business Media LLC,c 2009 |
338 | a print2 rdacarrier | |
520 | a We conducted a two-stage genome-wide association study of pancreatic cancer, a cancer with one of the lowest survival rates worldwide. We genotyped 558,542 SNPs in 1,896 individuals with pancreatic cancer and 1,939 controls drawn from 12 prospective cohorts plus one hospital-based case-control study. We conducted a combined analysis of these groups plus an additional 2,457 affected individuals and 2,654 controls from eight case-control studies, adjusting for study, sex, ancestry and five principal components. We identified an association between a locus on 9q34 and pancreatic cancer marked by the SNP rs505922 (combined P = 5.37 x 10(-8); multiplicative per-allele odds ratio 1.20; 95% confidence interval 1.12-1.28). This SNP maps to the first intron of the ABO blood group gene. Our results are consistent with earlier epidemiologic evidence suggesting that people with blood group O may have a lower risk of pancreatic cancer than those with groups A or B. | |
700 | 1 | a Kraft, Peter4 aut |
700 | 1 | a Stolzenberg-Solomon, Rachael Z4 aut |
700 | 1 | a Fuchs, Charles S4 aut |
700 | 1 | a Petersen, Gloria M4 aut |
700 | 1 | a Arslan, Alan A4 aut |
700 | 1 | a Bueno-de-Mesquita, H Bas4 aut |
700 | 1 | a Gross, Myron4 aut |
700 | 1 | a Helzlsouer, Kathy4 aut |
700 | 1 | a Jacobs, Eric J4 aut |
700 | 1 | a Lacroix, Andrea4 aut |
700 | 1 | a Zheng, Wei4 aut |
700 | 1 | a Albanes, Demetrius4 aut |
700 | 1 | a Bamlet, William4 aut |
700 | 1 | a Berg, Christine D4 aut |
700 | 1 | a Berrino, Franco4 aut |
700 | 1 | a Bingham, Sheila4 aut |
700 | 1 | a Buring, Julie E4 aut |
700 | 1 | a Bracci, Paige M4 aut |
700 | 1 | a Canzian, Federico4 aut |
700 | 1 | a Clavel-Chapelon, Françoise4 aut |
700 | 1 | a Clipp, Sandra4 aut |
700 | 1 | a Cotterchio, Michelle4 aut |
700 | 1 | a de Andrade, Mariza4 aut |
700 | 1 | a Duell, Eric J4 aut |
700 | 1 | a Fox Jr, John W4 aut |
700 | 1 | a Gallinger, Steven4 aut |
700 | 1 | a Gaziano, J Michael4 aut |
700 | 1 | a Giovannucci, Edward L4 aut |
700 | 1 | a Goggins, Michael4 aut |
700 | 1 | a González, Carlos A4 aut |
700 | 1 | a Hallmans, Göranu Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001 |
700 | 1 | a Hankinson, Susan E4 aut |
700 | 1 | a Hassan, Manal4 aut |
700 | 1 | a Holly, Elizabeth A4 aut |
700 | 1 | a Hunter, David J4 aut |
700 | 1 | a Hutchinson, Amy4 aut |
700 | 1 | a Jackson, Rebecca4 aut |
700 | 1 | a Jacobs, Kevin B4 aut |
700 | 1 | a Jenab, Mazda4 aut |
700 | 1 | a Kaaks, Rudolf4 aut |
700 | 1 | a Klein, Alison P4 aut |
700 | 1 | a Kooperberg, Charles4 aut |
700 | 1 | a Kurtz, Robert C4 aut |
700 | 1 | a Li, Donghui4 aut |
700 | 1 | a Lynch, Shannon M4 aut |
700 | 1 | a Mandelson, Margaret4 aut |
700 | 1 | a McWilliams, Robert R4 aut |
700 | 1 | a Mendelsohn, Julie B4 aut |
700 | 1 | a Michaud, Dominique S4 aut |
700 | 1 | a Olson, Sara H4 aut |
700 | 1 | a Overvad, Kim4 aut |
700 | 1 | a Patel, Alpa V4 aut |
700 | 1 | a Peeters, Petra H M4 aut |
700 | 1 | a Rajkovic, Aleksandar4 aut |
700 | 1 | a Riboli, Elio4 aut |
700 | 1 | a Risch, Harvey A4 aut |
700 | 1 | a Shu, Xiao-Ou4 aut |
700 | 1 | a Thomas, Gilles4 aut |
700 | 1 | a Tobias, Geoffrey S4 aut |
700 | 1 | a Trichopoulos, Dimitrios4 aut |
700 | 1 | a Van Den Eeden, Stephen K4 aut |
700 | 1 | a Virtamo, Jarmo4 aut |
700 | 1 | a Wactawski-Wende, Jean4 aut |
700 | 1 | a Wolpin, Brian M4 aut |
700 | 1 | a Yu, Herbert4 aut |
700 | 1 | a Yu, Kai4 aut |
700 | 1 | a Zeleniuch-Jacquotte, Anne4 aut |
700 | 1 | a Chanock, Stephen J4 aut |
700 | 1 | a Hartge, Patricia4 aut |
700 | 1 | a Hoover, Robert N4 aut |
710 | 2 | a Umeå universitetb Näringsforskning4 org |
773 | 0 | t Nature Geneticsd : Springer Science and Business Media LLCg 41, s. 986-990q 41<986-990x 1061-4036x 1546-1718 |
856 | 4 | u https://europepmc.org/articles/pmc2839871?pdf=render |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-25443 |
856 | 4 8 | u https://doi.org/10.1038/ng.429 |
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