SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:DiVA.org:uu-197069"
 

Sökning: onr:"swepub:oai:DiVA.org:uu-197069" > Insights into the e...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004147naa a2200565 4500
001oai:DiVA.org:uu-197069
003SwePub
008130318s2013 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1970692 URI
0247 a https://doi.org/10.1186/1471-2164-14-952 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Rands, Chris M.4 aut
2451 0a Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence
264 c 2013-02-12
264 1b Springer Science and Business Media LLC,c 2013
338 a electronic2 rdacarrier
520 a Background: A classical example of repeated speciation coupled with ecological diversification is the evolution of 14 closely related species of Darwin's (Galapagos) finches (Thraupidae, Passeriformes). Their adaptive radiation in the Galapagos archipelago took place in the last 2-3 million years and some of the molecular mechanisms that led to their diversification are now being elucidated. Here we report evolutionary analyses of genome of the large ground finch, Geospiza magnirostris. Results: 13,291 protein-coding genes were predicted from a 991.0 Mb G. magnirostris genome assembly. We then defined gene orthology relationships and constructed whole genome alignments between the G. magnirostris and other vertebrate genomes. We estimate that 15% of genomic sequence is functionally constrained between G. magnirostris and zebra finch. Genic evolutionary rate comparisons indicate that similar selective pressures acted along the G. magnirostris and zebra finch lineages suggesting that historical effective population size values have been similar in both lineages. 21 otherwise highly conserved genes were identified that each show evidence for positive selection on amino acid changes in the Darwin's finch lineage. Two of these genes (Igf2r and Pou1f1) have been implicated in beak morphology changes in Darwin's finches. Five of 47 genes showing evidence of positive selection in early passerine evolution have cilia related functions, and may be examples of adaptively evolving reproductive proteins. Conclusions: These results provide insights into past evolutionary processes that have shaped G. magnirostris genes and its genome, and provide the necessary foundation upon which to build population genomics resources that will shed light on more contemporaneous adaptive and non-adaptive processes that have contributed to the evolution of the Darwin's finches.
653 a Genomics
653 a Evolution
653 a Darwin's finches
653 a Large ground finch
653 a Geospiza magnirostris
7001 a Darling, Aaron4 aut
7001 a Fujita, Matthew4 aut
7001 a Kong, Lesheng4 aut
7001 a Webster, Matthew T.u Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)maweb226
7001 a Clabaut, Celine4 aut
7001 a Emes, Richard D.4 aut
7001 a Heger, Andreas4 aut
7001 a Meader, Stephen4 aut
7001 a Hawkins, Michael Brent4 aut
7001 a Eisen, Michael B.4 aut
7001 a Teiling, Clotilde4 aut
7001 a Affourtit, Jason4 aut
7001 a Boese, Benjamin4 aut
7001 a Grant, Peter R.4 aut
7001 a Grant, Barbara Rosemary4 aut
7001 a Eisen, Jonathan A.4 aut
7001 a Abzhanov, Arhat4 aut
7001 a Ponting, Chris P.4 aut
7102 a Uppsala universitetb Institutionen för medicinsk biokemi och mikrobiologi4 org
7730 t BMC Genomicsd : Springer Science and Business Media LLCg 14, s. 95-q 14<95-x 1471-2164
8564 u https://uu.diva-portal.org/smash/get/diva2:611618/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://bmcgenomics.biomedcentral.com/track/pdf/10.1186/1471-2164-14-95
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-197069
8564 8u https://doi.org/10.1186/1471-2164-14-95

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy