Sökning: onr:"swepub:oai:DiVA.org:uu-342666" > The role of depress...
Fältnamn | Indikatorer | Metadata |
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000 | 04051naa a2200397 4500 | |
001 | oai:DiVA.org:uu-342666 | |
003 | SwePub | |
008 | 180227s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3426662 URI |
024 | 7 | a https://doi.org/10.1097/CMR.00000000000003802 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Gogas, Helen J.u Laikon Gen Hosp, Dept Med 1, Athens, Greece.4 aut |
245 | 1 0 | a The role of depression and personality traits in patients with melanoma :b a South-European study |
264 | 1 | b LIPPINCOTT WILLIAMS & WILKINS,c 2017 |
338 | a print2 rdacarrier | |
520 | a We explored the potential association of depression history and personality, evaluated through a robust questionnaire tool, namely the Eysenck Personality Scale, with disease risk and progression among Greek patients. A total of 106 melanoma patients and their 1 : 1 sex-matched controls were interviewed on the basis of a questionnaire comprising phenotypic, sociodemographic, lifestyle and medical history variables, as well as information on history of lifetime major depression. The Eysenck Personality Questionnaire, measuring the four personality dimensions (extraversion, neuroticism, psychoticism, lie), was thereafter completed. Adjusted odds ratios (ORs) for melanoma risk were derived through multiple logistic regression analyses, whereas potential predictors of survival were explored using Cox proportional hazards models. Sun sensitivity score [OR: 1.55, 95% confidence interval (CI): 1.16-2.06] and major depression history (OR: 5.72, 95% CI: 1.38-23.73) were significantly associated with melanoma, whereas inverse associations of extraversion (OR: 0.90, 95% CI: 0.83-0.97) and psychoticism score (OR: 0.88, 95% CI: 0.78-1.00) were noted. These associations were more pronounced and remained solely among female patients; notably, decreased extraversion (OR: 0.86, 95% CI: 0.76-0.98) and psychoticism score (OR: 0.63, 95% CI: 0.43-0.91), as well as increased depression history (OR: 10.69, 95% CI: 1.43-80.03) were evident. Cox-derived hazard ratios showed nonsignificant associations of depression history and personality with disease outcome. Our data support the hypotheses that depression history and personality are associated with melanoma risk. No effect on survival after cancer diagnosis was observed. If confirmed in future studies, these associations may contribute toward better understanding the etiology of melanoma, enhancing health-related quality of life. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a depression history | |
653 | a Eysenck Personality Questionnaire | |
653 | a malignant melanoma risk | |
653 | a personality traits | |
653 | a survival | |
700 | 1 | a Karalexi, Maria A.u Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 aut |
700 | 1 | a Dessypris, Nicku Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 aut |
700 | 1 | a Antoniadis, Antonios G.u Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 aut |
700 | 1 | a Papadopoulos, Fotios,d 1976-u Uppsala universitet,Psykiatri, Akademiska sjukhuset4 aut0 (Swepub:uu)fotpa105 |
700 | 1 | a Petridou, Eleni T.u Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 aut |
710 | 2 | a Laikon Gen Hosp, Dept Med 1, Athens, Greece.b Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 org |
773 | 0 | t Melanoma researchd : LIPPINCOTT WILLIAMS & WILKINSg 27:6, s. 625-631q 27:6<625-631x 0960-8931x 1473-5636 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-342666 |
856 | 4 8 | u https://doi.org/10.1097/CMR.0000000000000380 |
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