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Sökning: onr:"swepub:oai:DiVA.org:uu-342666" > The role of depress...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004051naa a2200397 4500
001oai:DiVA.org:uu-342666
003SwePub
008180227s2017 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3426662 URI
024a https://doi.org/10.1097/CMR.00000000000003802 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Gogas, Helen J.u Laikon Gen Hosp, Dept Med 1, Athens, Greece.4 aut
2451 0a The role of depression and personality traits in patients with melanoma :b a South-European study
264 1b LIPPINCOTT WILLIAMS & WILKINS,c 2017
338 a print2 rdacarrier
520 a We explored the potential association of depression history and personality, evaluated through a robust questionnaire tool, namely the Eysenck Personality Scale, with disease risk and progression among Greek patients. A total of 106 melanoma patients and their 1 : 1 sex-matched controls were interviewed on the basis of a questionnaire comprising phenotypic, sociodemographic, lifestyle and medical history variables, as well as information on history of lifetime major depression. The Eysenck Personality Questionnaire, measuring the four personality dimensions (extraversion, neuroticism, psychoticism, lie), was thereafter completed. Adjusted odds ratios (ORs) for melanoma risk were derived through multiple logistic regression analyses, whereas potential predictors of survival were explored using Cox proportional hazards models. Sun sensitivity score [OR: 1.55, 95% confidence interval (CI): 1.16-2.06] and major depression history (OR: 5.72, 95% CI: 1.38-23.73) were significantly associated with melanoma, whereas inverse associations of extraversion (OR: 0.90, 95% CI: 0.83-0.97) and psychoticism score (OR: 0.88, 95% CI: 0.78-1.00) were noted. These associations were more pronounced and remained solely among female patients; notably, decreased extraversion (OR: 0.86, 95% CI: 0.76-0.98) and psychoticism score (OR: 0.63, 95% CI: 0.43-0.91), as well as increased depression history (OR: 10.69, 95% CI: 1.43-80.03) were evident. Cox-derived hazard ratios showed nonsignificant associations of depression history and personality with disease outcome. Our data support the hypotheses that depression history and personality are associated with melanoma risk. No effect on survival after cancer diagnosis was observed. If confirmed in future studies, these associations may contribute toward better understanding the etiology of melanoma, enhancing health-related quality of life. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a depression history
653 a Eysenck Personality Questionnaire
653 a malignant melanoma risk
653 a personality traits
653 a survival
700a Karalexi, Maria A.u Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 aut
700a Dessypris, Nicku Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 aut
700a Antoniadis, Antonios G.u Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 aut
700a Papadopoulos, Fotios,d 1976-u Uppsala universitet,Psykiatri, Akademiska sjukhuset4 aut0 (Swepub:uu)fotpa105
700a Petridou, Eleni T.u Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 aut
710a Laikon Gen Hosp, Dept Med 1, Athens, Greece.b Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.4 org
773t Melanoma researchd : LIPPINCOTT WILLIAMS & WILKINSg 27:6, s. 625-631q 27:6<625-631x 0960-8931x 1473-5636
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-342666
8564 8u https://doi.org/10.1097/CMR.0000000000000380

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