Sökning: onr:"swepub:oai:gup.ub.gu.se/212983" > Dairy products and ...
Fältnamn | Indikatorer | Metadata |
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000 | 08433naa a2201645 4500 | |
001 | oai:gup.ub.gu.se/212983 | |
003 | SwePub | |
008 | 240910s2014 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:54acdc1a-d925-48a1-825d-1acc915342e7 | |
009 | oai:DiVA.org:umu-95216 | |
009 | oai:prod.swepub.kib.ki.se:129575601 | |
024 | 7 | a https://gup.ub.gu.se/publication/2129832 URI |
024 | 7 | a https://doi.org/10.1002/ijc.288122 DOI |
024 | 7 | a https://lup.lub.lu.se/record/46561402 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-952162 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1295756012 URI |
040 | a (SwePub)gud (SwePub)lud (SwePub)umud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Duarte-Salles, T.4 aut |
245 | 1 0 | a Dairy products and risk of hepatocellular carcinoma: The European Prospective Investigation into Cancer and Nutrition |
264 | c 2014-03-07 | |
264 | 1 | b Wiley-Liss Inc.c 2014 |
520 | a Intake of dairy products has been associated with risk of some cancers, but findings are often inconsistent and information on hepatocellular carcinoma (HCC) risk is limited, particularly from prospective settings. The aim of our study was to investigate the association between consumption of total and specific dairy products (milk/cheese/yogurt) and their components (calcium/vitamin D/fats/protein), with first incident HCC (Ncases = 191) in the European Prospective Investigation into Cancer and Nutrition cohort, including a nested case-control subset (Ncases = 122) with the assessment of hepatitis B virus/hepatitis C virus infections status, liver damage and circulating insulin-like growth factor (IGF)-I levels. For cohort analyses, multivariable-adjusted Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CI). For nested case-control analyses, conditional logistic regression was used to calculate odds ratios and 95% CI. A total of 477,206 participants were followed-up for an average of 11 years (person-years follow-up = 5,415,385). In the cohort study, a significant positive HCC risk association was observed for total dairy products (highest vs. lowest tertile, HR = 1.66, 95% CI: 1.13-2.43; ptrend = 0.012), milk (HR = 1.51, 95% CI: 1.02-2.24; ptrend = 0.049), and cheese (HR = 1.56, 95% CI: 1.02-2.38; ptrend = 0.101), but not yogurt (HR = 0.94, 95% CI: 0.65-1.35). Dietary calcium, vitamin D, fat and protein from dairy sources were associated with increased HCC risk, whereas the same nutrients from nondairy sources showed inverse or null associations. In the nested case-control study, similar results were observed among hepatitis-free individuals. Results from this large prospective cohort study suggest that higher consumption of dairy products, particularly milk and cheese, may be associated with increased HCC risk. Validation of these findings in other populations is necessary. Potential biologic mechanisms require further exploration. What's New? Currently, the role of dairy product intake in the development of hepatocellular carcinoma (HCC) is unclear. Using detailed data from a large multi-centric prospective cohort, this study investigated the association between consumption of total and specific dairy products with first incident HCC. The study found that higher dairy product consumption, particularly milk and cheese, was associated with increased HCC risk. Dietary calcium, vitamin D, fat and protein did not explain the observed associations. However, higher circulating IGF-I levels may play a role. © 2014 UICC. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a calcium | |
653 | a dairy products | |
653 | a hepatocellular carcinoma | |
653 | a prospective cohort | |
653 | a fat | |
653 | a protein | |
653 | a somatomedin C | |
653 | a vitamin D | |
653 | a adult | |
653 | a aged | |
653 | a article | |
653 | a calcium intake | |
653 | a cancer risk | |
653 | a case control study | |
653 | a cheese | |
653 | a cohort analysis | |
653 | a controlled study | |
653 | a dairy product | |
653 | a dietary intake | |
653 | a disease association | |
653 | a Europe | |
653 | a fat content | |
653 | a fat intake | |
653 | a female | |
653 | a follow up | |
653 | a food composition | |
653 | a hepatitis B | |
653 | a hepatitis C | |
653 | a human | |
653 | a liver cell carcinoma | |
653 | a liver injury | |
653 | a major clinical study | |
653 | a male | |
653 | a medical society | |
653 | a milk | |
653 | a nutritional assessment | |
653 | a priority journal | |
653 | a prospective study | |
653 | a protein content | |
653 | a protein intake | |
653 | a risk factor | |
653 | a very elderly | |
653 | a vitamin intake | |
653 | a Aged | |
653 | a 80 and over | |
653 | a Carcinoma | |
653 | a Hepatocellular | |
653 | a Case-Control Studies | |
653 | a Follow-Up Studies | |
653 | a Humans | |
653 | a Liver Neoplasms | |
653 | a Middle Aged | |
653 | a Nutritional Status | |
653 | a Prognosis | |
653 | a Prospective Studies | |
653 | a Risk Factors | |
653 | a Young Adult | |
700 | 1 | a Fedirko, V.4 aut |
700 | 1 | a Stepien, M.4 aut |
700 | 1 | a Trichopoulou, A.4 aut |
700 | 1 | a Bamia, C.4 aut |
700 | 1 | a Lagiou, P.4 aut |
700 | 1 | a Lukanova, Annekatrinu Umeå universitet,Patologi4 aut0 (Swepub:umu)anlu0225 |
700 | 1 | a Trepo, E.4 aut |
700 | 1 | a Overvad, K.4 aut |
700 | 1 | a Tjønneland, A.4 aut |
700 | 1 | a Halkjær, J.4 aut |
700 | 1 | a Boutron-Ruault, M. C.4 aut |
700 | 1 | a Racine, A.4 aut |
700 | 1 | a Cadeau, C.4 aut |
700 | 1 | a Kühn, T.4 aut |
700 | 1 | a Aleksandrova, K.4 aut |
700 | 1 | a Trichopoulos, D.4 aut |
700 | 1 | a Tsiotas, K.4 aut |
700 | 1 | a Boffetta, P.4 aut |
700 | 1 | a Palli, D.4 aut |
700 | 1 | a Pala, V.4 aut |
700 | 1 | a Tumino, R.4 aut |
700 | 1 | a Sacerdote, C.4 aut |
700 | 1 | a Panico, S.4 aut |
700 | 1 | a Bueno-de-Mesquita, H. B.4 aut |
700 | 1 | a Dik, V. K.4 aut |
700 | 1 | a Peeters, P. H.4 aut |
700 | 1 | a Weiderpass, E.u Karolinska Institutet4 aut |
700 | 1 | a Torhild Gram, I.4 aut |
700 | 1 | a Hjartåker, A.4 aut |
700 | 1 | a Ramõn Quirõs, J.4 aut |
700 | 1 | a Fonseca-Nunes, A.4 aut |
700 | 1 | a Molina-Montes, E.4 aut |
700 | 1 | a Dorronsoro, M.4 aut |
700 | 1 | a Navarro Sanchez, C.4 aut |
700 | 1 | a Barricarte, A.4 aut |
700 | 1 | a Lindkvist, Björnu Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xlibjo |
700 | 1 | a Sonestedt, Emilyu Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups4 aut0 (Swepub:lu)medf-eso |
700 | 1 | a Johansson, Ingegerdu Umeå universitet,Institutionen för odontologi4 aut0 (Swepub:umu)injo0003 |
700 | 1 | a Wennberg, Mariau Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)mawe0024 |
700 | 1 | a Khaw, K. T.4 aut |
700 | 1 | a Wareham, N.4 aut |
700 | 1 | a Travis, R. C.4 aut |
700 | 1 | a Romieu, I.4 aut |
700 | 1 | a Riboli, E.4 aut |
700 | 1 | a Jenab, M.4 aut |
710 | 2 | a Umeå universitetb Patologi4 org |
773 | 0 | t International Journal of Cancerd : Wiley-Liss Inc.g 135:7, s. 1662-1672q 135:7<1662-1672x 0020-7136x 1097-0215 |
856 | 4 | u http://dx.doi.org/10.1002/ijc.28812y FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/212983 |
856 | 4 8 | u https://doi.org/10.1002/ijc.28812 |
856 | 4 8 | u https://lup.lub.lu.se/record/4656140 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-95216 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:129575601 |
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