Sökning: onr:"swepub:oai:gup.ub.gu.se/298385" > Large Artery Athero...
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000 | 06010naa a2200685 4500 | |
001 | oai:gup.ub.gu.se/298385 | |
003 | SwePub | |
008 | 240910s2021 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2983852 URI |
024 | 7 | a https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.1054632 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Fitzgerald, Seán4 aut |
245 | 1 0 | a Large Artery Atherosclerotic Clots are Larger than Clots of other Stroke Etiologies and have Poorer Recanalization rates. |
264 | 1 | b Elsevier BV,c 2021 |
520 | a There is a paucity of knowledge in the literature relating to the extent of clot burden and stroke etiology. In this study, we measured the Extracted Clot Area (ECA) retrieved during endovascular treatment (EVT) and investigated relationships with suspected etiology, administration of intravenous thrombolysis and recanalization.As part of the multi-institutional RESTORE registry, the ECA retrieved during mechanical thrombectomy was quantified using ImageJ. The effect of stroke etiology (Large-artery atherosclerosis (LAA), Cardioembolism, Cryptogenic and other) and recombinant tissue plasminogen activator (rtPA) on ECA and recanalization outcome (mTICI) was assessed. Successful recanalization was described as mTICI 2c-3.A total of 550 patients who underwent EVT with any clot retrieved were included in the study. The ECA was significantly larger in the LAA group compared to all other etiologies. The average ECA size of each etiology was; LAA=109mm2, Cardioembolic=52mm2, Cryptogenic=47mm2 and Other=52mm2 (p=0.014*). LAA patients also had a significantly poorer rate of successful recanalization (mTICI 2c-3) compared to all other etiologies (p=0.003*). The administration of tPA was associated with a smaller ECA in both LAA (p=0.007*) and cardioembolic (p=0.035*) groups.The ECA of LAA clots was double the size of all other etiologies and this is associated with a lower rate of successful recanalization in LAA stroke subtype. rtPA administration prior to thrombectomy was associated with reduced ECA in LAA and CE clots. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
700 | 1 | a Rossi, Rosanna4 aut |
700 | 1 | a Mereuta, Oana Madalina4 aut |
700 | 1 | a Molina, Sara4 aut |
700 | 1 | a Okolo, Adaobi4 aut |
700 | 1 | a Douglas, Andrew4 aut |
700 | 1 | a Jabrah, Duaa4 aut |
700 | 1 | a Pandit, Abhay4 aut |
700 | 1 | a McCarthy, Ray4 aut |
700 | 1 | a Gilvarry, Michael4 aut |
700 | 1 | a Ceder, Eriku Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology4 aut |
700 | 1 | a Dehlfors, Niclasu Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology4 aut |
700 | 1 | a Dunker, Dennisu Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology4 aut |
700 | 1 | a Nordanstig, Annika,d 1974u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xnoraz |
700 | 1 | a Redfors, Petrau Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xredpe |
700 | 1 | a Jood, Katarina,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xjooka |
700 | 1 | a Magoufis, Georgios4 aut |
700 | 1 | a Psychogios, Klearchos4 aut |
700 | 1 | a Tsivgoulis, Georgios4 aut |
700 | 1 | a Alderson, Jack4 aut |
700 | 1 | a O'Hare, Alan4 aut |
700 | 1 | a Power, Sarah4 aut |
700 | 1 | a Brennan, Paul4 aut |
700 | 1 | a Nagy, András4 aut |
700 | 1 | a Vadász, Ágnes4 aut |
700 | 1 | a Brinjikji, Waleed4 aut |
700 | 1 | a Kallmes, David4 aut |
700 | 1 | a Szikora, Istvan4 aut |
700 | 1 | a Tatlisumak, Turgutu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xtatlt |
700 | 1 | a Rentzos, Alexandros,d 1979u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology4 aut0 (Swepub:gu)xrenta |
700 | 1 | a Thornton, John4 aut |
700 | 1 | a Doyle, Karen M4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för radiologi4 org |
773 | 0 | t Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Associationd : Elsevier BVg 30:1q 30:1x 1532-8511 |
773 | 0 | t Journal of Stroke and Cerebrovascular Diseasesd : Elsevier BVg 30:1q 30:1x 1052-3057 |
856 | 4 | u http://www.strokejournal.org/article/S1052305720308818/pdf |
856 | 4 8 | u https://gup.ub.gu.se/publication/298385 |
856 | 4 8 | u https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105463 |
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