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Sökning: onr:"swepub:oai:lup.lub.lu.se:59dff426-97fc-4f02-9280-e7b368ab814f" > Protocol for outcom...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008216naa a2200793 4500
001oai:lup.lub.lu.se:59dff426-97fc-4f02-9280-e7b368ab814f
003SwePub
008200430s2020 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:143706782
009oai:gup.ub.gu.se/294265
024a https://lup.lub.lu.se/record/59dff426-97fc-4f02-9280-e7b368ab814f2 URI
024a https://doi.org/10.1016/j.resuscitation.2020.03.0042 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1437067822 URI
024a https://gup.ub.gu.se/publication/2942652 URI
040 a (SwePub)lud (SwePub)kid (SwePub)gu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Lilja, Giselau Lund University,Lunds universitet,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-gal
2451 0a Protocol for outcome reporting and follow-up in the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2)
264 1b Elsevier BV,c 2020
300 a 9 s.
520 a Aims: The TTM2-trial is a multi-centre randomised clinical trial where targeted temperature management (TTM) at 33 °C will be compared with normothermia and early treatment of fever (≥37.8 °C) after Out-of-Hospital Cardiac Arrest (OHCA). This paper presents the design and rationale of the TTM2-trial follow-up, where information on secondary and exploratory outcomes will be collected. We also present the explorative outcome analyses which will focus on neurocognitive function and societal participation in OHCA-survivors. Methods: Blinded outcome-assessors will perform follow-up at 30-days after the OHCA with a telephone interview, including the modified Rankin Scale (mRS) and the Glasgow Outcome Scale Extended (GOSE). Face-to-face meetings will be performed at 6 and 24-months, and include reports on outcome from several sources of information: clinician-reported: mRS, GOSE; patient-reported: EuroQol-5 Dimensions-5 Level responses version (EQ-5D-5L), Life satisfaction, Two Simple Questions; observer-reported: Informant Questionnaire on Cognitive Decline in the Elderly-Cardiac Arrest version (IQCODE-CA) and neurocognitive performance measures: Montreal Cognitive Assessment, (MoCA), Symbol Digit Modalities Test (SDMT). Exploratory analyses will be performed with an emphasis on brain injury in the survivors, where the two intervention groups will be compared for potential differences in neuro-cognitive function (MoCA, SDMT) and societal participation (GOSE). Strategies to increase inter-rater reliability and decrease missing data are described. Discussion: The TTM2-trial follow-up is a pragmatic yet detailed pre-planned and standardised assessment of patient's outcome designed to ensure data-quality, decrease missing data and provide optimal conditions to investigate clinically relevant effects of TTM, including OHCA-survivors’ neurocognitive function and societal participation.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Anestesi och intensivvård0 (SwePub)302012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Anesthesiology and Intensive Care0 (SwePub)302012 hsv//eng
653 a Cardiac arrest
653 a Cognitive function
653 a Patient Reported Outcome Measures
653 a Quality of life
653 a Treatment outcome
700a Nielsen, Niklasu Lund University,Lunds universitet,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Center for cardiac arrest,Lund University Research Groups,Helsingborg Hospital4 aut0 (Swepub:lu)med-nni
700a Ullén, Susannu Skåne University Hospital4 aut0 (Swepub:lu)su7040ul
700a Blennow Nordstrom, Eriku Lund University,Lunds universitet,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)er0251bl
700a Dankiewicz, Josefu Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)med-jfd
700a Friberg, Hansu Lund University,Lunds universitet,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)efor-hfr
700a Heimburg, Katarinau Lund University,Lunds universitet,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)ka7876he
700a Jakobsen, Janus Christianu Holbæk Hospital,University of Southern Denmark4 aut
700a Levin, Helenau Lund University,Lunds universitet,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)ores-hal
700a Callaway, Cliftonu University of Pittsburgh4 aut
700a Cariou, Alainu Paris Descartes University,Cochin Hospital4 aut
700a Eastwood, Glenn M.u Monash University4 aut
700a Helbok, Raimundu Medical University of Innsbruck4 aut
700a Hovdenes, Janu Oslo university hospital4 aut
700a Kirkegaard, Hansu Aarhus University,Aarhus University Hospital4 aut
700a Leithner, Christophu Charité - University Medicine Berlin4 aut
700a Morgan, Matt P.G.u University Hospital of Wales4 aut
700a Nordberg, Peru Karolinska Institutet,Karolinska Institute4 aut
700a Oddo, Maurou University of Lausanne,Lausanne University Hospital4 aut
700a Pelosi, Paolou Ospedale Policlinico San Martino,University of Genoa4 aut
700a Rylander, Christian,d 1960u Gothenburg University,Göteborgs universitet,University of Gothenburg,Sahlgrenska University Hospital,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care4 aut0 (Swepub:gu)xrylch
700a Saxena, Manoju University of New South Wales,Bankstown-Lidcombe Hospital4 aut
700a Taccone, Fabio Silviou Hospital Erasme,Université Libre de Bruxelles (ULB)4 aut
700a Siranec, Michalu Charles University in Prague,General University Hospital in Prague4 aut
700a Wise, Matthew P.u University Hospital of Wales4 aut
700a Young, Paul J.u Medical Research Institute of New Zealand4 aut
700a Cronberg, Tobiasu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups4 aut0 (Swepub:lu)efor-tcr
710a Brain Injury After Cardiac Arrestb Forskargrupper vid Lunds universitet4 org
773t Resuscitationd : Elsevier BVg 150, s. 104-112q 150<104-112x 0300-9572x 1873-1570
856u http://dx.doi.org/10.1016/j.resuscitation.2020.03.004x freey FULLTEXT
856u http://www.resuscitationjournal.com/article/S0300957220301131/pdf
8564 8u https://lup.lub.lu.se/record/59dff426-97fc-4f02-9280-e7b368ab814f
8564 8u https://doi.org/10.1016/j.resuscitation.2020.03.004
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:143706782
8564 8u https://gup.ub.gu.se/publication/294265

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