Sökning: onr:"swepub:oai:lup.lub.lu.se:59dff426-97fc-4f02-9280-e7b368ab814f" > Protocol for outcom...
Fältnamn | Indikatorer | Metadata |
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000 | 08216naa a2200793 4500 | |
001 | oai:lup.lub.lu.se:59dff426-97fc-4f02-9280-e7b368ab814f | |
003 | SwePub | |
008 | 200430s2020 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:143706782 | |
009 | oai:gup.ub.gu.se/294265 | |
024 | 7 | a https://lup.lub.lu.se/record/59dff426-97fc-4f02-9280-e7b368ab814f2 URI |
024 | 7 | a https://doi.org/10.1016/j.resuscitation.2020.03.0042 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1437067822 URI |
024 | 7 | a https://gup.ub.gu.se/publication/2942652 URI |
040 | a (SwePub)lud (SwePub)kid (SwePub)gu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Lilja, Giselau Lund University,Lunds universitet,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-gal |
245 | 1 0 | a Protocol for outcome reporting and follow-up in the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2) |
264 | 1 | b Elsevier BV,c 2020 |
300 | a 9 s. | |
520 | a Aims: The TTM2-trial is a multi-centre randomised clinical trial where targeted temperature management (TTM) at 33 °C will be compared with normothermia and early treatment of fever (≥37.8 °C) after Out-of-Hospital Cardiac Arrest (OHCA). This paper presents the design and rationale of the TTM2-trial follow-up, where information on secondary and exploratory outcomes will be collected. We also present the explorative outcome analyses which will focus on neurocognitive function and societal participation in OHCA-survivors. Methods: Blinded outcome-assessors will perform follow-up at 30-days after the OHCA with a telephone interview, including the modified Rankin Scale (mRS) and the Glasgow Outcome Scale Extended (GOSE). Face-to-face meetings will be performed at 6 and 24-months, and include reports on outcome from several sources of information: clinician-reported: mRS, GOSE; patient-reported: EuroQol-5 Dimensions-5 Level responses version (EQ-5D-5L), Life satisfaction, Two Simple Questions; observer-reported: Informant Questionnaire on Cognitive Decline in the Elderly-Cardiac Arrest version (IQCODE-CA) and neurocognitive performance measures: Montreal Cognitive Assessment, (MoCA), Symbol Digit Modalities Test (SDMT). Exploratory analyses will be performed with an emphasis on brain injury in the survivors, where the two intervention groups will be compared for potential differences in neuro-cognitive function (MoCA, SDMT) and societal participation (GOSE). Strategies to increase inter-rater reliability and decrease missing data are described. Discussion: The TTM2-trial follow-up is a pragmatic yet detailed pre-planned and standardised assessment of patient's outcome designed to ensure data-quality, decrease missing data and provide optimal conditions to investigate clinically relevant effects of TTM, including OHCA-survivors’ neurocognitive function and societal participation. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Anestesi och intensivvård0 (SwePub)302012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Anesthesiology and Intensive Care0 (SwePub)302012 hsv//eng |
653 | a Cardiac arrest | |
653 | a Cognitive function | |
653 | a Patient Reported Outcome Measures | |
653 | a Quality of life | |
653 | a Treatment outcome | |
700 | 1 | a Nielsen, Niklasu Lund University,Lunds universitet,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Center for cardiac arrest,Lund University Research Groups,Helsingborg Hospital4 aut0 (Swepub:lu)med-nni |
700 | 1 | a Ullén, Susannu Skåne University Hospital4 aut0 (Swepub:lu)su7040ul |
700 | 1 | a Blennow Nordstrom, Eriku Lund University,Lunds universitet,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)er0251bl |
700 | 1 | a Dankiewicz, Josefu Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)med-jfd |
700 | 1 | a Friberg, Hansu Lund University,Lunds universitet,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)efor-hfr |
700 | 1 | a Heimburg, Katarinau Lund University,Lunds universitet,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)ka7876he |
700 | 1 | a Jakobsen, Janus Christianu Holbæk Hospital,University of Southern Denmark4 aut |
700 | 1 | a Levin, Helenau Lund University,Lunds universitet,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)ores-hal |
700 | 1 | a Callaway, Cliftonu University of Pittsburgh4 aut |
700 | 1 | a Cariou, Alainu Paris Descartes University,Cochin Hospital4 aut |
700 | 1 | a Eastwood, Glenn M.u Monash University4 aut |
700 | 1 | a Helbok, Raimundu Medical University of Innsbruck4 aut |
700 | 1 | a Hovdenes, Janu Oslo university hospital4 aut |
700 | 1 | a Kirkegaard, Hansu Aarhus University,Aarhus University Hospital4 aut |
700 | 1 | a Leithner, Christophu Charité - University Medicine Berlin4 aut |
700 | 1 | a Morgan, Matt P.G.u University Hospital of Wales4 aut |
700 | 1 | a Nordberg, Peru Karolinska Institutet,Karolinska Institute4 aut |
700 | 1 | a Oddo, Maurou University of Lausanne,Lausanne University Hospital4 aut |
700 | 1 | a Pelosi, Paolou Ospedale Policlinico San Martino,University of Genoa4 aut |
700 | 1 | a Rylander, Christian,d 1960u Gothenburg University,Göteborgs universitet,University of Gothenburg,Sahlgrenska University Hospital,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care4 aut0 (Swepub:gu)xrylch |
700 | 1 | a Saxena, Manoju University of New South Wales,Bankstown-Lidcombe Hospital4 aut |
700 | 1 | a Taccone, Fabio Silviou Hospital Erasme,Université Libre de Bruxelles (ULB)4 aut |
700 | 1 | a Siranec, Michalu Charles University in Prague,General University Hospital in Prague4 aut |
700 | 1 | a Wise, Matthew P.u University Hospital of Wales4 aut |
700 | 1 | a Young, Paul J.u Medical Research Institute of New Zealand4 aut |
700 | 1 | a Cronberg, Tobiasu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups4 aut0 (Swepub:lu)efor-tcr |
710 | 2 | a Brain Injury After Cardiac Arrestb Forskargrupper vid Lunds universitet4 org |
773 | 0 | t Resuscitationd : Elsevier BVg 150, s. 104-112q 150<104-112x 0300-9572x 1873-1570 |
856 | 4 | u http://dx.doi.org/10.1016/j.resuscitation.2020.03.004x freey FULLTEXT |
856 | 4 | u http://www.resuscitationjournal.com/article/S0300957220301131/pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/59dff426-97fc-4f02-9280-e7b368ab814f |
856 | 4 8 | u https://doi.org/10.1016/j.resuscitation.2020.03.004 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:143706782 |
856 | 4 8 | u https://gup.ub.gu.se/publication/294265 |
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