Sökning: onr:"swepub:oai:lup.lub.lu.se:a33bd6a2-241b-4dde-ad53-165c843455af" > Differences in lodg...
Fältnamn | Indikatorer | Metadata |
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000 | 02494naa a2200337 4500 | |
001 | oai:lup.lub.lu.se:a33bd6a2-241b-4dde-ad53-165c843455af | |
003 | SwePub | |
008 | 160401s1988 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/11040732 URI |
024 | 7 | a https://doi.org/10.1007/BF017535752 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Blomqvist, G4 aut |
245 | 1 0 | a Differences in lodgement of tumour cells in muscle and liver |
264 | 1 | c 1988 |
520 | a Differences in the lodgement of circulating tumour cells in various organs are considered an important factor in metastatic organ selection. The present vital microscopic studies show that the pattern of intravascular arrest of tumour cells in muscle after intra-arterial injection is similar to that observed earlier, in the liver, after intraportal injection. However, parallel isotope studies on the lodgement process (at 5 min and 3 h after injection) showed that the tumour cells trapped in the muscle microvasculature were destroyed at a higher rate than in the liver. Tumour cells kept in test tubes, and thus not being subjected to the shearing forces of the circulation, had a higher survival rate than cells trapped in the muscle. The results indicate that stronger retardation forces acting on the tumour cells in muscle (arterial dissemination) than in the liver (venous dissemination) may be one mechanism behind the increased tumour cell destruction in muscle. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
700 | 1 | a Skolnik, G4 aut |
700 | 1 | a Braide, M4 aut |
700 | 1 | a Bjursten, Lars Magnusu Lund University,Lunds universitet,Institutionen för experimentell medicinsk vetenskap,Medicinska fakulteten,Department of Experimental Medical Science,Faculty of Medicine4 aut0 (Swepub:lu)exp-lbj |
700 | 1 | a Blixt, A4 aut |
700 | 1 | a Bagge, U4 aut |
710 | 2 | a Institutionen för experimentell medicinsk vetenskapb Medicinska fakulteten4 org |
773 | 0 | t Clinical and Experimental Metastasisg 6:4, s. 285-289q 6:4<285-289x 1573-7276 |
856 | 4 | u http://dx.doi.org/10.1007/BF01753575y FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/1104073 |
856 | 4 8 | u https://doi.org/10.1007/BF01753575 |
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