Computer-assisted calculation of myocardial infarct size shortens the evaluation time of contrast-enhanced cardiac MRI

• Background: Delayed enhancement magnetic resonance imaging depicts scar in the left ventricle which can be quantitatively measured. Manual segmentation and scar determination is time consuming. The purpose of this study was to evaluate a software for infarct quantification, to compare with manual scar determination, and to measure the time saved.Methods: Delayed enhancement magnetic resonance imaging was performed in 40 patients where myocardial perfusion single photon emission computed tomography imaging showed irreversible uptake reduction suggesting a myocardial scar. After segmentation, the semi-automatic software was applied. A scar area was displayed, which could be corrected and compared with manual delineation. The different time steps were recorded with both methods.Results: The software shortened the average evaluation time by 12.4min per cardiac exam, compared with manual delineation. There was good correlation of myocardial volume, infarct volume and infarct percentage (%) between the two methods, r = 0.95, r = 0.92 and r = 0.91 respectively.Conclusions: A computer software for myocardial volume and infarct size determination cut the evaluation time by more than 50% compared with manual assessment, with maintained clinical accuracy.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Physiology (hsv//eng)

Nyckelord

Computer software

Magnetic resonance imaging

Myocardial infarct size

Semi-automatic

Time saving

accuracy

adult

aged

article

clinical article

clinical effectiveness

computer analysis

computer program

contrast enhancement

correlation analysis

female

heart infarction size

heart muscle perfusion

heart volume

human

image analysis

intermethod comparison

male

nuclear magnetic resonance imaging

priority journal

quantitative analysis

scar formation

single photon emission computer tomography

time

Aged

80 and over

Algorithms

Contrast Media

Gadolinium DTPA

Humans

Image Interpretation

Computer-Assisted

Magnetic Resonance Imaging

Cine

Middle Aged

Myocardial Infarction

Observer Variation

Predictive Value of Tests

Prognosis

Reproducibility of Results

Software

Time Factors

Tomography

Emission-Computed

Single-Photon

Radiology

Cardiology

time saving

semi-automatic

magnetic resonance imaging

computer software

myocardial infarct size

MEDICINE

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