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Population-based st...
Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms
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- Kahn, Robin (author)
- Lund University,Lunds universitet,Lund Pediatric Rheumatology Research Group,Forskargrupper vid Lunds universitet,Barnreumatologiskt forskningscentrum,WCMM- Wallenberg center för molekylär medicinsk forskning,Medicinska fakulteten,Lund University Research Groups,Center of Pediatric Rheumatology,WCMM-Wallenberg Centre for Molecular Medicine,Faculty of Medicine
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- Berg, Stefan, 1959 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Queen Silvia Children’s Hospital
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- Berntson, Lillemor, 1957- (author)
- Uppsala University,Uppsala universitet,Pediatrisk inflammations- och metabolismforskning samt barnhälsa
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- Berthold, Elisabet (author)
- Lund University,Lunds universitet,Barnreumatologiskt forskningscentrum,Forskargrupper vid Lunds universitet,Center of Pediatric Rheumatology,Lund University Research Groups
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- Brodin, Petter (author)
- Karolinska Institutet
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- Bäckström, Fredrik (author)
- Norrland University Hospital
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- Compagno, Michele (author)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Reumatologi,Forskargrupper vid Lunds universitet,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups
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- Fasth, Anders, 1945 (author)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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- Lingman Framme, Jenny, 1977 (author)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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- Horne, Anna Carin (author)
- Karolinska Institutet
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- Hätting, Josefin (author)
- Skaraborg Hospital
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- Król, Petra (author)
- Lund University,Lunds universitet,Barnreumatologiskt forskningscentrum,Forskargrupper vid Lunds universitet,Center of Pediatric Rheumatology,Lund University Research Groups
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- Kukka, Antti (author)
- Uppsala University,Uppsala universitet,Global hälsa - implementering och hållbarhet,Department of Paediatrics, Gävle, Sweden
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- Mossberg, Maria (author)
- Karolinska Institutet,Lund University,Lunds universitet,Barninfektioner och global barn- och ungdomshälsa,Forskargrupper vid Lunds universitet,Pediatrik infectious diseases and global child health,Lund University Research Groups
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- Månsson, Bengt (author)
- Lund University,Lunds universitet,Lund Pediatric Rheumatology Research Group,Forskargrupper vid Lunds universitet,Barnreumatologiskt forskningscentrum,Lund University Research Groups,Center of Pediatric Rheumatology
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- Nordenhäll, Charlotta (author)
- Sachs’ Children and Youth Hospital
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- Idring Nordström, Selma (author)
- Karolinska Institutet
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- Khammari Nyström, Fatine (author)
- Karolinska Institutet
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- Palmblad, Karin (author)
- Karolinska Institutet
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- Rasti, Reza (author)
- Karolinska Institutet
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- Rudolph, André (author)
- Karolinska Institutet
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- Rydenman, Karin, 1982 (author)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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- Sundberg, Erik (author)
- Karolinska Institutet
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- Säve-Söderbergh, Eva (author)
- Sunderby Hospital
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- Altman, Maria (author)
- Karolinska University Hospital
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- Horne, AnnaCarin (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2021-12
- 2022
- English.
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In: Acta Paediatrica, International Journal of Paediatrics. - : Wiley. - 0803-5253 .- 1651-2227. ; 111:2, s. 354-62
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Abstract
Subject headings
Close
- Aim: Our aim was to describe the outcomes of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. Methods: This national, population-based, longitudinal, multicentre study used Swedish data that were prospectively collected between 1 December 2020 and 31 May 2021. All patients met the World Health Organization criteria for MIS-C. The outcomes 2 and 8weeks after diagnosis are presented, and follow-up protocols are suggested. Results: We identified 152 cases, and 133 (87%) participated. When followed up 2weeks after MIS-C was diagnosed, 43% of the 119 patients had abnormal results, including complete blood cell counts, platelet counts, albumin levels, electrocardiograms and echocardiograms. After 8weeks, 36% of 89 had an abnormal patient history, but clinical findings were uncommon. Echocardiogram results were abnormal in 5% of 67, and the most common complaint was fatigue. Older children and those who received intensive care were more likely to report symptoms and have abnormal cardiac results. Conclusion: More than a third (36%) of the patients had persistent symptoms 8weeks after MIS-C, and 5% had abnormal echocardiograms. Older age and higher levels of initial care appeared to be risk factors. Structured follow-up visits are important after MIS-C.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- abnormal echocardiograms
- fatigue
- intensive care
- outcomes
- persistent symptoms
- abnormal echocardiograms
Publication and Content Type
- ref (subject category)
- art (subject category)
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Kahn, Robin
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Berg, Stefan, 19 ...
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Berntson, Lillem ...
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Berthold, Elisab ...
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Brodin, Petter
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Bäckström, Fredr ...
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show more...
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Compagno, Michel ...
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Fasth, Anders, 1 ...
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Lingman Framme, ...
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Horne, Anna Cari ...
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Hätting, Josefin
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Król, Petra
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Kukka, Antti
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Mossberg, Maria
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Månsson, Bengt
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Nordenhäll, Char ...
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Idring Nordström ...
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Khammari Nyström ...
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Palmblad, Karin
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Rasti, Reza
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Rudolph, André
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Rydenman, Karin, ...
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Sundberg, Erik
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Säve-Söderbergh, ...
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Altman, Maria
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Horne, AnnaCarin
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Rheumatology and ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Pediatrics
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Gastroenterology ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Orthopaedics
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Infectious Medic ...
- Articles in the publication
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Acta Paediatrica ...
- By the university
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University of Gothenburg
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Uppsala University
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Lund University
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Karolinska Institutet