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Conservative or sur...
Conservative or surgical management of orbital schwannomas : a population-based case series
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- El-Hajj, Victor Gabriel (författare)
- Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
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- Singh, Aman (författare)
- Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
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- Norin, Cecilia (författare)
- St Erik Eye Hosp, Div Ophthalmol & Vis, Stockholm, Sweden.
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- Edström, Erik (författare)
- Karolinska Institutet
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- Bohman, Elin (författare)
- Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.;St Erik Eye Hosp, Div Ophthalmol & Vis, Stockholm, Sweden.
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- Elmi-Terander, Adrian (författare)
- Karolinska Institutet,Uppsala universitet,Ortopedi och Handkirurgi,Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.;Löwenströmska Hosp, Capio Spine Ctr Stockholm, POB 2074, S-19402 Upplands Väsby, Sweden.
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Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden St Erik Eye Hosp, Div Ophthalmol & Vis, Stockholm, Sweden. (creator_code:org_t)
- Springer, 2024
- 2024
- Engelska.
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Ingår i: Acta Neurochirurgica. - : Springer. - 0001-6268 .- 0942-0940. ; 166
- Relaterad länk:
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Abstract
Ämnesord
Stäng
- Introduction: Orbital schwannomas (OS) are rare occurrences with no more than 500 cases reported in the literature. The tumor's potential to compromise the delicate neuro-ophthalmic structures within the orbit prompts surgical removal. Tumor removal is performed by ophthalmologists, often requiring a multidisciplinary surgical approach. The literature contains a very limited number of cases managed non-surgically. However, the inherent risks of orbital surgery warrant a comparison of the outcomes of conservative and surgical management strategies.Aims: To review the national Swedish experience with the management of orbital schwannomas.Methods: The study center is the primary Swedish referral center for the multidisciplinary management of orbital tumors, including schwannomas. During the period of 2005 to 2021, 16 patients with an OS diagnosis were managed at the center.Results: Four patients initially underwent surgery where gross total resection (GTR) was achieved in three (75%) and subtotal resection (STR) in one (25%) case. The remaining 12 patients, who had a low risk of neuro-ophthalmic impairment, were managed conservatively with radiological and clinical examinations at regular intervals. After an average follow-up of 17 months, surgery was performed in three of these cases (25%). No recurrences or tumor growths were detected on radiological follow-ups (mean 50 months), and all patients experienced postoperative improvement at clinical follow-up (mean 65 months). The remainder of the conservatively treated patients (n=9) experienced no clinical progression (mean 30 months). A slight radiological tumor progression was detected in one patient after 17 months.Conclusion: There were no differences in long-term outcome between patients who had been managed with early surgery and those operated later after an initially conservative management. Conservatively treated patients had minimal to no symptoms and remained clinically stable throughout the follow-up period. Based on these findings, conservative management may successfully be adopted in cases with mild symptoms, no signs of compressive optic neuropathy and low risk of neuro-ophthalmic impairment. Conversion to surgical management is indicated upon clinical deterioration or tumor growth. Based on the findings of this study a decision tree for the management of orbital schwannomas is suggested.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Schwannomas
- Orbit
- Orbital schwannomas
- Surgery
- Watchful waiting
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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