Sökning: L773:0007 0920 OR L773:1532 1827 >
Overall survival of...
Overall survival of patients with metastatic breast cancer in Sweden : a nationwide study
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- Valachis, Antonis, 1984- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Oncology, Faculty of Medicine and Health, Örebro University Hospital, Örebro, Sweden,Örebro Univ Hosp, Fac Med & Hlth, Dept Oncol, S-70105 Örebro, Sweden
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- Carlqvist, Peter (författare)
- Nordic Market Access AB, S-11359 Stockholm, Sweden
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- Ma, Yuanjun (författare)
- Parexel International, Stockholm, Sweden,Parexel Int, S-10359 Stockholm, Sweden
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- Szilcz, Máté (författare)
- Karolinska Institutet
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- Freilich, Jonatan (författare)
- Umeå universitet,Avdelningen för medicin,Parexel International, Stockholm, Sweden,Parexel Int, S-10359 Stockholm, Sweden.;Umeå Univ, Dept Publ Hlth & Clin Med, S-90187 Umeå, Sweden
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- Vertuani, Simona (författare)
- Novartis Sverige AB, S-16428 Kista, Sweden
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- Holm, Barbro (författare)
- Novartis Sverige AB, S-16428 Kista, Sweden
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- Lindman, Henrik (författare)
- Uppsala universitet,Experimentell och klinisk onkologi
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(creator_code:org_t)
- 2022-05-21
- 2022
- Engelska.
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Ingår i: British Journal of Cancer. - : Nature Publishing Group. - 0007-0920 .- 1532-1827. ; 127:4, s. 720-725
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Breast cancer is the most common cancer among women in Sweden. Whereas survival for the overall breast cancer population is well-documented, survival of patients with metastatic breast cancer (MBC) is harder to quantify due to the lack of reliable data on disease recurrence in national cancer registers.Methods: This study used machine learning to classify the total MBC population in Sweden diagnosed between 2009 and 2016 using national registers, with the aim to estimate overall survival (OS).Results: The total population consisted of 13,832 patients-2528 (18.3%) had de novo MBC whereas 11,304 (81.7%) were classed as having a recurrent MBC. Median OS for patients with MBC was found to be 29.8 months 95% confidence interval (CI) [28.9, 30.6]. Hormone-receptor (HR)-positive MBC had a median OS of 37.0 months 95% CI [35.9, 38.3] compared to 9.9 months 95% CI [9.1, 11.0] for patients with HR-negative MBC.Conclusion: This study covered the entire MBC population in Sweden during the study time and may serve as a baseline for assessing the effect of new treatment strategies in MBC introduced after the study period.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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