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Evolutionary aspect...
Evolutionary aspects of the genomic organization of rat chromosome 10.
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- Behboudi, Afrouz, 1967 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi, genetik,Department of Cell and Molecular Biology, Genetics,University of Gothenburg,Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University, Sweden
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- Sjöstrand, Eleonor (author)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi,Department of Cell and Molecular Biology,University of Gothenburg,Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University, Sweden
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- Gómez-Fabre, Pedro M (author)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi,Department of Cell and Molecular Biology,University of Gothenburg,Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University, Sweden
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- Sjöling, Åsa, 1968 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi, genetik,Department of Cell and Molecular Biology, Genetics,University of Gothenburg,Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University, Sweden
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- Taib, Ziad, 1953 (author)
- Department of Mathematics, Chalmers University of Technology, Göteborg, Sweden
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- Klinga-Levan, Karin, 1951- (author)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi,Department of Cell and Molecular Biology,University of Gothenburg,Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University, Sweden
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- Ståhl, Fredrik, 1956 (author)
- Högskolan i Borås,Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi, genetik,Department of Cell and Molecular Biology, Genetics,University of Gothenburg,Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University, Sweden,Institutionen för Vårdvetenskap
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- Levan, Göran, 1939 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi, genetik,Department of Cell and Molecular Biology, Genetics,University of Gothenburg,Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University, Sweden ; CMB-Genetics, Göteborg, Sweden
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(creator_code:org_t)
- S. Karger, 2002
- 2002
- English.
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In: Cytogenetic and genome research. - : S. Karger. - 1424-8581 .- 1424-859X. ; 96:1-4, s. 52-9
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Abstract
Subject headings
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- Using FISH and RH mapping a chromosomal map of rat chromosome 10 (RNO10) was constructed. Our mapping data were complemented by other published data and the final map was compared to maps of mouse and human chromosomes. RNO10 contained segments homologous to mouse chromosomes (MMU) 11, 16 and 17, with evolutionary breakpoints between the three segments situated in the proximal part of RNO10. Near one of these breakpoints (between MMU17 and 11) we found evidence for an inversion ancestral to the mouse that was not ancestral to the condition in the rat. Within each of the chromosome segments identified, the gene order appeared to be largely conserved. This conservation was particularly clear in the long MMU11-homologous segment. RNO10 also contained segments homologous to three human chromosomes (HSA5, 16, 17). However, within each segment of conserved synteny were signs of more extensive rearrangements. At least 13 different evolutionary breakpoints were indicated in the rat-human comparison. In contrast to what was found between rat and mouse, the rat-human evolutionary breaks were distributed along the entire length of RNO10.
Subject headings
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Keyword
- Animals
- Base Sequence
- Chromosome Mapping
- DNA Primers
- Evolution
- Genetic Markers
- In Situ Hybridization
- Fluorescence
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- Rats
- genetics
- Animals
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Behboudi, Afrouz ...
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Sjöstrand, Eleon ...
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Gómez-Fabre, Ped ...
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Sjöling, Åsa, 19 ...
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Taib, Ziad, 1953
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Klinga-Levan, Ka ...
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show more...
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Ståhl, Fredrik, ...
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Levan, Göran, 19 ...
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Genetics
- Articles in the publication
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Cytogenetic and ...
- By the university
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University of Gothenburg
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Chalmers University of Technology
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University of Skövde
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University of Borås