Sökning: onr:"swepub:oai:DiVA.org:oru-115533" >
Effect of treatment...
Effect of treatment for early gestational diabetes mellitus on neonatal respiratory distress : A secondary analysis of the TOBOGM study
-
- Simmons, David (författare)
- School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
-
- Immanuel, Jincy (författare)
- School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
-
- Hague, William M. (författare)
- Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia
-
visa fler...
-
- Coat, Suzette (författare)
- Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia
-
- Teede, Helena (författare)
- Department of Medicine, Monash University, Melbourne, Victoria, Australia
-
- Nolan, Christopher J. (författare)
- Department of Medicine, Canberra Hospital and Australian National University, Canberra, Australian Capital Territory, Australia
-
- Peek, Michael J. (författare)
- School of Medicine and Psychology, Australian National University, Canberra, Australian Capital Territory, Australia
-
- Flack, Jeff R. (författare)
- Department of Medicine, Bankstown-Lidcombe Hospital, Sydney, New South Wales, Australia
-
- McLean, Mark (författare)
- Department of Medicine, Blacktown Hospital, Sydney, New South Wales, Australia
-
- Wong, Vincent W. (författare)
- Department of Medicine, Liverpool Hospital and University of New South Wales, Sydney, New South Wales, Australia
-
- Hibbert, Emily J. (författare)
- Nepean Clinical School, Faculty of Medicine and Health, University of Sydney and Nepean Hospital, Sydney, New South Wales, Australia
-
- Kautzky-Willer, Alexandra (författare)
- Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria
-
- Harreiter, Jürgen (författare)
- Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria; Department of Medicine, Landesklinikum Scheibbs, Scheibbs, Austria
-
- Backman, Helena, 1965- (författare)
- Örebro universitet,Institutionen för hälsovetenskaper,Department of Obstetrics and Gynecology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
-
- Gianatti, Emily (författare)
- Endocrinology and Diabetes, Fiona Stanley and Fremantle Hospitals, Murdoch, Western Australia, Australia
-
- Sweeting, Arianne (författare)
- Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
-
- Mohan, Viswanathan (författare)
- Dr. Mohan's Diabetes Specialities Centre and Madras Diabetes Research Foundation, Chennai, India
-
- Cheung, N. Wah (författare)
- Department of Medicine, Westmead Hospital, Sydney, New South Wales, Australia
-
visa färre...
-
(creator_code:org_t)
- 2024
- 2024
- Engelska.
-
Ingår i: British Journal of Obstetrics and Gynecology. - : John Wiley & Sons. - 1470-0328 .- 1471-0528.
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- OBJECTIVE: To identify factors associated with neonatal respiratory distress (NRD) in early Gestational diabetes mellitus (eGDM).DESIGN: Nested case-control analysis of the TOBOGM trial.SETTING: Seventeen hospitals: Australia, Sweden, Austria and India. POPULATION: Pregnant women, <20 weeks' gestation, singleton, GDM risk factors.METHODS: Women with GDM risk factors completed an oral glucose tolerance test (OGTT) before 20 weeks: those with eGDM (WHO-2013 criteria) were randomised to immediate or deferred GDM treatment. Logistic regression compared pregnancies with/without NRD, and in pregnancies with NRD, those with/without high-dependency nursery admission for ≤24 h with those admitted for >24 h. Comparisons were adjusted for age, pre-pregnancy body mass index, ethnicity, smoking, primigravity, education and site. Adjusted odds ratios (95% CI) are reported.MAIN OUTCOME MEASURES: NRD definition: ≥4 h of respiratory support (supplemental oxygen or supported ventilation) postpartum. Respiratory distress syndrome (RDS): Supported ventilation and ≥24 h nursery stay.RESULTS: Ninety-nine (12.5%) of 793 infants had NRD; incidence halved (0.50, 0.31-0.79) if GDM treatment was started early. NRD was associated with Caesarean section (2.31, 1.42-3.76), large for gestational age (LGA) (1.83, 1.09-3.08) and shorter gestation (0.95, 0.93-0.97 per day longer). Among NRD infants, >24 h nursery-stay was associated with higher OGTT 1-h glucose (1.38, 1.08-1.76 per mmol/L). Fifteen (2.0%) infants had RDS.CONCLUSIONS: Identifying and treating eGDM reduces NRD risk. NRD is more likely with Caesarean section, LGA and shorter gestation. Further studies are needed to understand the mechanisms behind this eGDM complication and any long-term effects.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Nyckelord
- diagnostic criteria
- early gestational diabetes mellitus
- first trimester
- gestational diabetes mellitus
- neonatal intensive care
- neonatal respiratory distress
- pregnancy
- screening
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Simmons, David
-
Immanuel, Jincy
-
Hague, William M ...
-
Coat, Suzette
-
Teede, Helena
-
Nolan, Christoph ...
-
visa fler...
-
Peek, Michael J.
-
Flack, Jeff R.
-
McLean, Mark
-
Wong, Vincent W.
-
Hibbert, Emily J ...
-
Kautzky-Willer, ...
-
Harreiter, Jürge ...
-
Backman, Helena, ...
-
Gianatti, Emily
-
Sweeting, Ariann ...
-
Mohan, Viswanath ...
-
Cheung, N. Wah
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Reproduktionsmed ...
- Artiklar i publikationen
-
British Journal ...
- Av lärosätet
-
Örebro universitet