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Sökning: onr:"swepub:oai:DiVA.org:oru-86803" > Beneficial Role of ...

Beneficial Role of Replacing Dietary Saturated Fatty Acids with Polyunsaturated Fatty Acids in the Prevention of Sarcopenia : Findings from the NU-AGE Cohort

Montiel Rojas, Diego, 1984- (författare)
Örebro universitet,Institutionen för hälsovetenskaper
Santoro, Aurelia (författare)
Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; Alma Mater Research Institute on Global Challenges and Climate Change (Alma Climate), University of Bologna, Bologna, Italy
Nilsson, Andreas, 1973- (författare)
Örebro universitet,Institutionen för hälsovetenskaper
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Franceschi, Claudio (författare)
Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; Department of Applied Mathematics, Institute of Information Technology, Mathematics and Mechanics (ITMM), Lobachevsky State University of Nizhny Novgorod-National Research University (UNN), Nizhny, Novgorod, Russia
Capri, Miriam (författare)
Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; Alma Mater Research Institute on Global Challenges and Climate Change (Alma Climate), University of Bologna, Bologna, Italy
Bazzocchi, Alberto (författare)
Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Battista, Giuseppe (författare)
Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy
de Groot, Lisette C. P. G. M. (författare)
Department of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands
Feskens, Edith J. M. (författare)
Department of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands
Berendsen, Agnes A. M. (författare)
Department of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands
Bialecka-Debek, Agata (författare)
Department of Human Nutrition, Warsaw University of Life Sciences-SGGW, Warsaw, Poland
Surala, Olga (författare)
Department of Human Nutrition, Warsaw University of Life Sciences-SGGW, Warsaw, Poland
Pietruszka, Barbara (författare)
Department of Human Nutrition, Warsaw University of Life Sciences-SGGW, Warsaw, Poland
Fairweather-Tait, Susan (författare)
Norwich Medical School, University of East Anglia, Norwich, UK
Jennings, Amy (författare)
Norwich Medical School, University of East Anglia, Norwich, UK
Capel, Frederic (författare)
Unité de Nutrition Humaine (UNH), Institut National de Recherche pour L'agriculture, L'alimentation et L'environnement (INRAE), Université Clermont Auvergne, CRNH Auvergne, Clermont-Ferrand, France
Kadi, Fawzi, 1970- (författare)
Örebro universitet,Institutionen för hälsovetenskaper
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 (creator_code:org_t)
2020-10-09
2020
Engelska.
Ingår i: Nutrients. - : MDPI. - 2072-6643. ; 12:10
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Dietary fat subtypes may play an important role in the regulation of muscle mass and function during ageing. The aim of the present study was to determine the impact of isocaloric macronutrient substitutions, including different fat subtypes, on sarcopenia risk in older men and women, while accounting for physical activity (PA) and metabolic risk. A total of 986 participants, aged 65-79 years, completed a 7-day food record and wore an accelerometer for a week. A continuous sex-specific sarcopenia risk score (SRS), including skeletal muscle mass assessed by dual-energy X-ray absorptiometry (DXA) and handgrip strength, was derived. The impact of the isocaloric replacement of saturated fatty acids (SFAs) by either mono- (MUFAs) or poly-unsaturated (PUFAs) fatty acids on SRS was determined using regression analysis based on the whole sample and stratified by adherence to a recommended protein intake (1.1 g/BW). Isocaloric reduction of SFAs for the benefit of PUFAs was associated with a lower SRS in the whole population, and in those with a protein intake below 1.1 g/BW, after accounting for age, smoking habits, metabolic disturbances, and adherence to PA guidelines. The present study highlighted the potential of promoting healthy diets with optimised fat subtype distribution in the prevention of sarcopenia in older adults.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Näringslära (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nutrition and Dietetics (hsv//eng)

Nyckelord

Ageing
dietary fats
isocaloric substitution
macronutrients
metabolic syndrome
muscle mass
muscle strength
physical activity

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