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Regional differences in treatment for osteoporosis. The Global Longitudinal Study of Osteoporosis in Women (GLOW)

Díez-Pérez, Adolfo (författare)
Hospital del Mar-IMIM, Autonomous University of Barcelona and RETICEF, Instituto Carlos III, Barcelona, Spain
Hooven, Frederick H. (författare)
University of Massachusetts Medical School, Worcester, MA, USA
Adachi, Jonathan D. (författare)
St Joseph's Hospital, McMaster University, Hamilton, ON, Canada
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Adami, Silvano (författare)
University of Verona, Ospedale, Verona, Valeggio, Italy
Anderson, Frederick A. (författare)
University of Massachusetts Medical School, Worcester, MA, USA
Boonen, Steven (författare)
Leuven University Centre for Metabolic Bone Diseases, Division of Geriatric Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
Chapurlat, Roland (författare)
Université de Lyon, Department of Orthopedics and Rheumatology, Hôpital E Herriot, Lyon, France
Compston, Juliet E. (författare)
University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK
Cooper, Cyrus (författare)
University of Southampton, Southampton General Hospital and Norman Collisson Chair of Musculoskeletal Sciences, University of Oxford, Oxford, UK
Delmas, Pierre (författare)
Hôpital Edouard Herriot, Lyon, France
Greenspan, Susan L. (författare)
University of Pittsburgh, PA, USA
LaCroix, Andrea Z. (författare)
Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Lindsay, Robert (författare)
Regional Bone Center, Helen Hayes Hospital, West Haverstraw, NY, USA
Netelenbos, J. Coen (författare)
Department of Endocrinology, VU University Medical Center, Amsterdam, Netherlands
Pfeilschifter, Johannes (författare)
Alfried Krupp Krankenhaus, Department of Internal Medicine III, Essen, Germany
Roux, Christian (författare)
Paris Descartes University, Cochin Hospital, Paris, France
Saag, Kenneth G. (författare)
University of Alabama-Birmingham, Division of Clinical Immunology and Rheumatology, Birmingham, AL, USA
Sambrook, Philip (författare)
University of Sydney-Royal North Shore Hospital, St. Leonards, Sydney, NSW, Australia
Silverman, Stuart (författare)
Cedars-Sinai Medical Center, Los Angeles, CA, USA
Siris, Ethel S. (författare)
Columbia University Medical Center, New York, NY, USA
Watts, Nelson B. (författare)
Bone Health and Osteoporosis Center, University of Cincinnati, Cincinnati, OH, USA
Nika, Grigor (författare)
University of Massachusetts Medical School, Worcester, MA, USA
Gehlbach, Stephen H. (författare)
University of Massachusetts Medical School, Worcester, MA, USA
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 (creator_code:org_t)
Elsevier, 2011
2011
Engelska.
Ingår i: Bone. - : Elsevier. - 8756-3282 .- 1873-2763. ; 49:3, s. 493-498
Relaterad länk:
https://europepmc.or...
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https://urn.kb.se/re...
https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • PurposeTo determine if important geographic differences exist in treatment rates for osteoporosis and whether this variation can be explained by regional variation in risk factors.MethodsThe Global Longitudinal Study of Osteoporosis in Women is an observational study of women ≥ 55 years sampled from primary care practices in 10 countries. Self-administered questionnaires were used to collect data on patient characteristics, risk factors for fracture, previous fractures, anti-osteoporosis medication, and health status.ResultsAmong 58,009 women, current anti-osteoporosis medication use was lowest in Northern Europe (16%) and highest in USA and Australia (32%). Between 48% (USA, Southern Europe) and 68% (Northern Europe) of women aged ≥ 65 years with a history of spine or hip fracture since age 45 were untreated. Among women with osteoporosis, the percentage of treated cases was lowest in Europe (45–52% versus 62–65% elsewhere). Women with osteopenia and no other risk factors were treated with anti-osteoporosis medication most frequently in USA (31%) and Canada (31%), and least frequently in Southern Europe (12%), Northern Europe (13%), and Australia (16%). After adjusting for risk factors, US women were threefold as likely to be treated with anti-osteoporosis medication as Northern European women (odds ratio 2.8; 95% confidence interval 2.5–3.1) and 1.5 times as likely to be treated as Southern European women (1.5, 1.4–1.6). Up to half of women reporting previous hip or spine fracture did not receive treatment.ConclusionsThe likelihood of being treated for osteoporosis differed between regions, and cannot be explained by variation in risk factors. Many women at risk of fracture do not receive prophylaxis.

Ämnesord

NATURVETENSKAP  -- Matematik -- Sannolikhetsteori och statistik (hsv//swe)
NATURAL SCIENCES  -- Mathematics -- Probability Theory and Statistics (hsv//eng)

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