Sökning: WFRF:(Giles Graham G.)
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Alcohol consumption...
Alcohol consumption and breast cancer risk by estrogen receptor status : in a pooled analysis of 20 studies.
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- Jung, Seungyoun (författare)
- Harvard TH Chan School Public Heatlh, MA USA; University of Maryland, MD 21201 USA
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- Wang, Molin (författare)
- Harvard TH Chan School Public Heatlh, MA USA; Harvard TH Chan School Public Heatlh, MA USA
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- Anderson, Kristin (författare)
- University of Minnesota, MN USA; University of Minnesota, MN USA
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visa fler...
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- Baglietto, Laura (författare)
- Cancer Council Victoria, Australia; University of Melbourne, Australia
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- Bergkvist, Leif (författare)
- Uppsala universitet,Centrum för klinisk forskning, Västerås,Cent Hosp Vasteras, Dept Surg, Vasteras, Sweden,Central Hospital Vasteras, Sweden; Central Hospital Vasteras, Sweden
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- Bernstein, Leslie (författare)
- Beckman Research Institute, CA USA; City Hope National Medical Centre, CA 91010 USA
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- van den Brandt, Piet A (författare)
- Maastricht University, Netherlands
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- Brinton, Louise (författare)
- NCI, MD 20892 USA
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- Buring, Julie E (författare)
- Harvard TH Chan School Public Heatlh, MA USA; Harvard Medical Sch, MA USA
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- Heather Eliassen, A (författare)
- Harvard TH Chan School Public Heatlh, MA USA; Brigham and Womens Hospital, MA USA; Harvard Medical Sch, MA USA
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- Falk, Roni (författare)
- NCI, MD 20892 USA
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- Gapstur, Susan M (författare)
- Amer Cancer Soc, GA 30329 USA
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- Giles, Graham G (författare)
- Cancer Council Victoria, Australia; University of Melbourne, Australia,Fred Hutchinson Cancer Research Centre, WA 98104 USA,NCI, MD 20892 USA
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Goodman, Gary (författare)
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- Hoffman-Bolton, Judith (författare)
- Johns Hopkins Bloomberg School Public Heatlh, MD USA
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- Horn-Ross, Pamela L (författare)
- Cancer Prevent Institute Calif, CA USA
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- Inoue, Manami (författare)
- National Cancer Centre, Japan; University of Tokyo, Japan
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- Kolonel, Laurence N (författare)
- University of Hawaii, HI 96822 USA
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- Krogh, Vittorio (författare)
- Fdn IRCCS Ist Nazl Tumori, Italy
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- Löf, Marie (författare)
- Linköpings universitet,Karolinska Institutet,Avdelningen för kliniska vetenskaper,Medicinska fakulteten,Fred Hutchinson Cancer Research Centre, WA 98104 USA
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- Maas, Paige (författare)
- NCI, MD 20892 USA
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- Miller, Anthony B (författare)
- University of Toronto, Canada
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Neuhouser, Marian L (författare)
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- Park, Yikyung (författare)
- Washington University, MO 63110 USA
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- Robien, Kim (författare)
- George Washington University, DC USA
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- Rohan, Thomas E (författare)
- Albert Einstein Coll Med, NY 10467 USA
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- Scarmo, Stephanie (författare)
- NYU, NY USA
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- Schouten, Leo J (författare)
- Maastricht University, Netherlands
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- Sieri, Sabina (författare)
- Fdn IRCCS Ist Nazl Tumori, Italy
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- Stevens, Victoria L (författare)
- Amer Cancer Soc, GA 30329 USA
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- Tsugane, Schoichiro (författare)
- National Cancer Centre, Japan
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- Visvanathan, Kala (författare)
- Johns Hopkins Bloomberg School Public Heatlh, MD USA
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- Wilkens, Lynne R (författare)
- University of Hawaii, HI 96822 USA
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- Wolk, Alicja (författare)
- Karolinska Institutet,Karolinska Institute, Sweden
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- Weiderpass, Elisabete (författare)
- Karolinska Institutet,Karolinska Institute, Sweden; University of Tromso, Norway; Cancer Registry Norway, Norway; Folkhalsan Research Centre, Finland
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- Willett, Walter C (författare)
- Harvard TH Chan School Public Heatlh, MA USA; Harvard TH Chan School Public Heatlh, MA USA; Brigham and Womens Hospital, MA USA; Harvard Medical Sch, MA USA
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- Zeleniuch-Jacquotte, Anne (författare)
- NYU, NY USA
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- Zhang, Shumin M (författare)
- Harvard Medical Sch, MA USA
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- Zhang, Xuehong (författare)
- Brigham and Womens Hospital, MA USA; Harvard Medical Sch, MA USA
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Ziegler, Regina G (författare)
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- Smith-Warner, Stephanie A (författare)
- Harvard TH Chan School Public Heatlh, MA USA
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(creator_code:org_t)
- 2015-08-28
- 2016
- Engelska.
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Ingår i: International Journal of Epidemiology. - : Oxford University Press (OUP). - 0300-5771 .- 1464-3685. ; 45:3, s. 916-928
- Relaterad länk:
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https://academic.oup...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Breast cancer aetiology may differ by estrogen receptor (ER) status. Associations of alcohol and folate intakes with risk of breast cancer defined by ER status were examined in pooled analyses of the primary data from 20 cohorts.METHODS: During a maximum of 6-18 years of follow-up of 1 089 273 women, 21 624 ER+ and 5113 ER- breast cancers were identified. Study-specific multivariable relative risks (RRs) were calculated using Cox proportional hazards regression models and then combined using a random-effects model.RESULTS: Alcohol consumption was positively associated with risk of ER+ and ER- breast cancer. The pooled multivariable RRs (95% confidence intervals) comparing ≥ 30 g/d with 0 g/day of alcohol consumption were 1.35 (1.23-1.48) for ER+ and 1.28 (1.10-1.49) for ER- breast cancer (Ptrend ≤ 0.001; Pcommon-effects by ER status: 0.57). Associations were similar for alcohol intake from beer, wine and liquor. The associations with alcohol intake did not vary significantly by total (from foods and supplements) folate intake (Pinteraction ≥ 0.26). Dietary (from foods only) and total folate intakes were not associated with risk of overall, ER+ and ER- breast cancer; pooled multivariable RRs ranged from 0.98 to 1.02 comparing extreme quintiles. Following-up US studies through only the period before mandatory folic acid fortification did not change the results. The alcohol and folate associations did not vary by tumour subtypes defined by progesterone receptor status.CONCLUSIONS: Alcohol consumption was positively associated with risk of both ER+ and ER- breast cancer, even among women with high folate intake. Folate intake was not associated with breast cancer risk.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Alcohol; folate; breast cancer; estrogen receptor; progesterone receptor; pooled analyses; epidemiology; cohort study
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- ref (ämneskategori)
- art (ämneskategori)
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Jung, Seungyoun
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Wang, Molin
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Anderson, Kristi ...
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Baglietto, Laura
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Bergkvist, Leif
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Bernstein, Lesli ...
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visa fler...
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van den Brandt, ...
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Brinton, Louise
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Buring, Julie E
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Heather Eliassen ...
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Falk, Roni
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Gapstur, Susan M
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Giles, Graham G
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Goodman, Gary
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Hoffman-Bolton, ...
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Horn-Ross, Pamel ...
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Inoue, Manami
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Kolonel, Laurenc ...
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Krogh, Vittorio
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Löf, Marie
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Maas, Paige
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Miller, Anthony ...
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Neuhouser, Maria ...
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Park, Yikyung
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Robien, Kim
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Rohan, Thomas E
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Scarmo, Stephani ...
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Schouten, Leo J
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Sieri, Sabina
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Stevens, Victori ...
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Tsugane, Schoich ...
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Visvanathan, Kal ...
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Wilkens, Lynne R
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Wolk, Alicja
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Weiderpass, Elis ...
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Willett, Walter ...
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Zeleniuch-Jacquo ...
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Zhang, Shumin M
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Zhang, Xuehong
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Ziegler, Regina ...
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Smith-Warner, St ...
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