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ENIGMA-anxiety working group : Rationale for and organization of large-scale neuroimaging studies of anxiety disorders

Bas-Hoogendam, Janna Marie (författare)
Department of Developmental and Educational Psychology, Leiden University, Institute of Psychology, Leiden, Netherlands; Department of Psychiatry, Leiden University Medical Center, Leiden, Netherlands; Leiden Institute for Brain and Cognition, Leiden, Netherlands
Groenewold, Nynke A (författare)
Department of Psychiatry & Mental Health, University of Cape Town, Cape Town, South Africa
Aghajani, Moji (författare)
Department of Psychiatry, Amsterdam UMC / VUMC, Amsterdam, Netherlands; Department of Research & Innovation, GGZ inGeest, Amsterdam, Netherlands
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Freitag, Gabrielle F (författare)
National Institute of Mental Health, Emotion and Development Branch, Bethesda, Maryland, USA
Harrewijn, Anita (författare)
National Institute of Mental Health, Emotion and Development Branch, Bethesda, Maryland, USA
Hilbert, Kevin (författare)
Department of Psychology, Humboldt‐Universität zu Berlin, Berlin, Germany
Jahanshad, Neda (författare)
University of Southern California Keck School of Medicine, Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Los Angeles, California, USA
Thomopoulos, Sophia I (författare)
University of Southern California Keck School of Medicine, Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Los Angeles, California, USA
Thompson, Paul M (författare)
University of Southern California Keck School of Medicine, Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Los Angeles, California, USA
Veltman, Dick J (författare)
Department of Psychiatry, Amsterdam UMC / VUMC, Amsterdam, Netherlands
Winkler, Anderson M (författare)
National Institute of Mental Health, Emotion and Development Branch, Bethesda, Maryland, USA
Lueken, Ulrike (författare)
Department of Psychology, Humboldt‐Universität zu Berlin, Berlin, Germany
Pine, Daniel S (författare)
National Institute of Mental Health, Emotion and Development Branch, Bethesda, Maryland, USA
van der Wee, Nic J A (författare)
Department of Psychiatry, Leiden University Medical Center, Leiden, Netherlands; Leiden Institute for Brain and Cognition, Leiden, Netherlands
Stein, Dan J (författare)
Department of Psychiatry & Mental Health, University of Cape Town, Cape Town, South Africa; University of Cape Town, South African MRC Unit on Risk & Resilience in Mental Disorders, Cape Town, South Africa; University of Cape Town, Neuroscience Institute, Cape Town, South Africa
Åhs, Fredrik (författare)
Mittuniversitetet,Institutionen för psykologi och socialt arbete
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 (creator_code:org_t)
2020-07-03
2022
Engelska.
Ingår i: Human Brain Mapping. - : Wiley. - 1065-9471 .- 1097-0193. ; 43:1, s. 83-112
Relaterad länk:
https://doi.org/10.1...
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https://miun.diva-po... (primary) (Raw object)
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https://urn.kb.se/re...
https://doi.org/10.1...
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  • Forskningsöversikt (refereegranskat)
Abstract Ämnesord
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  • Anxiety disorders are highly prevalent and disabling but seem particularly tractable to investigation with translational neuroscience methodologies. Neuroimaging has informed our understanding of the neurobiology of anxiety disorders, but research has been limited by small sample sizes and low statistical power, as well as heterogenous imaging methodology. The ENIGMA-Anxiety Working Group has brought together researchers from around the world, in a harmonized and coordinated effort to address these challenges and generate more robust and reproducible findings. This paper elaborates on the concepts and methods informing the work of the working group to date, and describes the initial approach of the four subgroups studying generalized anxiety disorder, panic disorder, social anxiety disorder, and specific phobia. At present, the ENIGMA-Anxiety database contains information about more than 100 unique samples, from 16 countries and 59 institutes. Future directions include examining additional imaging modalities, integrating imaging and genetic data, and collaborating with other ENIGMA working groups. The ENIGMA consortium creates synergy at the intersection of global mental health and clinical neuroscience, and the ENIGMA-Anxiety Working Group extends the promise of this approach to neuroimaging research on anxiety disorders.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)
SAMHÄLLSVETENSKAP  -- Psykologi -- Psykologi (hsv//swe)
SOCIAL SCIENCES  -- Psychology -- Psychology (hsv//eng)

Nyckelord

amygdala
anxiety disorders
genetics
limbic system
magnetic resonance imaging
neuroimaging
prefrontal cortex

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