SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Heikkila P)
 

Sökning: WFRF:(Heikkila P) > Preterm birth and a...

Preterm birth and asthma and COPD in adulthood: a nationwide register study from two Nordic countries

Pulakka, A (författare)
Risnes, K (författare)
Metsala, J (författare)
visa fler...
Alenius, S (författare)
Heikkila, K (författare)
Nilsen, SM (författare)
Nasanen-Gilmore, P (författare)
Haaramo, P (författare)
Gissler, M (författare)
Karolinska Institutet
Opdahl, S (författare)
Kajantie, E (författare)
visa färre...
 (creator_code:org_t)
2023-03-29
2023
Engelska.
Ingår i: The European respiratory journal. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 61:6
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Preterm birth affects lungs in several ways but only few studies have follow-up until adulthood. We investigated the association of the entire spectrum of gestational ages with specialist care episodes for obstructive airway disease (asthma and chronic obstructive pulmonary disease, COPD) at age 18–50 years. We used nationwide register data on 706 717 people born 1987–1998 in Finland (4.8% preterm) and 1 669 528 born 1967–1999 in Norway (5.0% preterm). Care episodes of asthma and COPD were obtained from specialised healthcare registers, available in Finland 2005–2016 and in Norway 2008–2017. We used logistic regression to estimate odds ratios (OR) for having a care episode with either disease outcome. Odds of any obstructive airway disease in adulthood were 2–3-fold for those born <28 or 28–31 completed weeks, compared with those born full-term (39–41 completed weeks), persisting after adjustments. For individuals born at 32–33, 34–36 or 37–38 weeks, the odds were 1.1- to 1.5-fold. Associations were similar in the Finnish and the Norwegian data and among people aged 18–29 and 30–50 years. For COPD at age 30–50 years, the OR was 7.44 (95% CI 3.49–15.85) for those born <28 weeks, 3.18 (2.23–4.54) for those born 28–31 weeks, and 2.32 (1.72–3.12) for those born 32–33 weeks. Bronchopulmonary dysplasia in infancy increased the odds further for those born <28 and 32–31 weeks. Preterm birth is a risk factor for asthma and COPD in adulthood. The high odds of COPD calls for diagnostic vigilance when adults born very preterm present with respiratory symptoms.

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy