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Orthogonal P-wave m...
Orthogonal P-wave morphology, conventional P-wave indices, and the risk of atrial fibrillation in the general population using data from the Finnish Hospital Discharge Register
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- Eranti, Antti (författare)
- North Karelia Central Hospital
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- Carlson, Jonas (författare)
- Lund University,Lunds universitet,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Lund University Research Groups
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- Kenttä, Tuomas (författare)
- Oulu University Hospital,University of Oulu
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- Holmqvist, Fredrik (författare)
- Lund University,Lunds universitet,Clinical studies af Atrial Fibrillation,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital
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- Holkeri, Arttu (författare)
- Helsinki University Central Hospital,University of Helsinki
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- Haukilahti, M. Anette (författare)
- Oulu University Hospital,University of Oulu
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- Kerola, Tuomas (författare)
- Päijät-Häme Central Hospital
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- Aro, Aapo L. (författare)
- University of Helsinki,Helsinki University Central Hospital
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- Rissanen, Harri (författare)
- Finnish National Institute for Health and Welfare
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- Noponen, Kai (författare)
- University of Oulu
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- Seppänen, Tapio (författare)
- University of Oulu
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- Knekt, Paul (författare)
- Finnish National Institute for Health and Welfare
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- Heliövaara, Markku (författare)
- Finnish National Institute for Health and Welfare
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- Huikuri, Heikki V. (författare)
- University of Oulu,Oulu University Hospital
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- Junttila, M. Juhani (författare)
- Oulu University Hospital,University of Oulu
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- Platonov, Pyotr G. (författare)
- Lund University,Lunds universitet,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital
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(creator_code:org_t)
- 2020-06-18
- 2020
- Engelska 9 s.
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Ingår i: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. - : Oxford University Press (OUP). - 1532-2092. ; 22:8, s. 1173-1181
- Relaterad länk:
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http://dx.doi.org/10...
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http://jultika.oulu....
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- AIMS: Identifying subjects at high and low risk of atrial fibrillation (AF) is of interest. This study aims to assess the risk of AF associated with electrocardiographic (ECG) markers linked to atrial fibrosis: P-wave prolongation, 3rd-degree interatrial block, P-terminal force in lead V1, and orthogonal P-wave morphology. METHODS AND RESULTS: P-wave parameters were assessed in a representative Finnish population sample aged ≥30 years (n = 7217, 46.0% male, mean age 51.4 years). Subjects (n = 5489) with a readable ECG including the orthogonal leads, sinus rhythm, and a predefined orthogonal P-wave morphology type [positive in leads X and Y and either negative (Type 1) or ± biphasic (Type 2) in lead Z; Type 3 defined as positive in lead X and ± biphasic in lead Y], were followed 10 years from the baseline examinations (performed 1978-80). Subjects discharged with AF diagnosis after any-cause hospitalization (n = 124) were defined as having developed AF. Third-degree interatrial block was defined as P-wave ≥120 ms and the presence of ≥2 ± biphasic P waves in the inferior leads. Hazard ratios (HRs) and confidence intervals (CIs) were assessed with Cox models. Third-degree interatrial block (n = 103, HR 3.18, 95% CI 1.66-6.13; P = 0.001) and Type 3 morphology (n = 216, HR 3.01, 95% CI 1.66-5.45; P < 0.001) were independently associated with the risk of hospitalization with AF. Subjects with P-wave <110 ms and Type 1 morphology (n = 2074) were at low risk (HR 0.46, 95% CI 0.26-0.83; P = 0.006), compared to the rest of the subjects. CONCLUSION: P-wave parameters associate with the risk of hospitalization with AF.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Electrocardiography
- Interatrial block
- P wave
- P-terminal force
- Atrial fibrillation
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Eranti, Antti
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Carlson, Jonas
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Kenttä, Tuomas
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Holmqvist, Fredr ...
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Holkeri, Arttu
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Haukilahti, M. A ...
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visa fler...
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Kerola, Tuomas
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Aro, Aapo L.
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Rissanen, Harri
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Noponen, Kai
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Seppänen, Tapio
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Knekt, Paul
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Heliövaara, Mark ...
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Huikuri, Heikki ...
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Junttila, M. Juh ...
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Platonov, Pyotr ...
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visa färre...
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