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Laparoscopically as...
Laparoscopically assisted vs open colectomy for colon cancer : a meta-analysis
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Bonjer, H. Jacob (författare)
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Hop, Wim C. J. (författare)
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Nelson, Heidi (författare)
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visa fler...
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Sargent, Daniel J. (författare)
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Lacy, Antonio M. (författare)
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Castells, Antoni (författare)
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Guillou, Pierre J. (författare)
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Thorpe, Helen (författare)
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Brown, Julia (författare)
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Delgado, Salvadora (författare)
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Kuhrij, Esther (författare)
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- Haglind, Eva, 1947 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences
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- Påhlman, Lars (författare)
- Uppsala universitet,Kolorektalkirurgi
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(creator_code:org_t)
- 2007
- 2007
- Engelska.
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Ingår i: Archives of surgery (Chicago. 1960). - 0004-0010 .- 1538-3644. ; 142:3, s. 298-303
- Relaterad länk:
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http://www.ncbi.nlm....
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https://urn.kb.se/re...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- OBJECTIVE: To perform a meta-analysis of trials randomizing patients with colon cancer to laparoscopically assisted or open colectomy to enhance the power in determining whether laparoscopic colectomy for cancer is oncologically safe. DATA SOURCES: The databases of the Barcelona, Clinical Outcomes of Surgical Therapy (COST), Colon Cancer Laparoscopic or Open Resection (COLOR), and Conventional vs Laparoscopic-Assisted Surgery in Patients With Colorectal Cancer (CLASICC) trials were the data sources for the study. STUDY SELECTION: Patients who had at least 3 years of complete follow-up data were selected. DATA EXTRACTION: Patients who had undergone curative surgery before March 1, 2000, were studied. Three-year disease-free survival and overall survival were the primary outcomes of this analysis. DATA SYNTHESIS: Of 1765 patients, 229 were excluded, leaving 796 patients in the laparoscopically assisted arm and 740 patients in the open arm for analysis. Three-year disease-free survival rates in the laparoscopically assisted and open arms were 75.8% and 75.3%, respectively (95% confidence interval [CI] of the difference, -5% to 4%). The associated common hazard ratio (laparoscopically assisted vs open surgery with adjustment for sex, age, and stage) was 0.99 (95% CI, 0.80-1.22; P = .92). The 3-year overall survival rate after laparoscopic surgery was 82.2% and after open surgery was 83.5% (95% CI of the difference, -3% to 5%). The associated hazard ratio was 1.07 (95% CI, 0.83-1.37; P = .61). Disease-free and overall survival rates for stages I, II, and III evaluated separately did not differ between the 2 treatments. CONCLUSION: Laparoscopically assisted colectomy for cancer is oncologically safe.
Nyckelord
- Colectomy/*methods
- Colonic Neoplasms/*surgery
- Follow-Up Studies
- Humans
- Laparoscopy
- Randomized Controlled Trials
- Treatment Outcome
- MEDICINE
- MEDICIN
- Colectomy/*methods
- Colonic Neoplasms/*surgery
- Follow-Up Studies
- Humans
- *Laparoscopy
- Randomized Controlled Trials
- Treatment Outcome
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Bonjer, H. Jacob
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Hop, Wim C. J.
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Nelson, Heidi
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Sargent, Daniel ...
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Lacy, Antonio M.
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Castells, Antoni
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visa fler...
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Guillou, Pierre ...
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Thorpe, Helen
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Brown, Julia
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Delgado, Salvado ...
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Kuhrij, Esther
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Haglind, Eva, 19 ...
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Påhlman, Lars
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visa färre...
- Artiklar i publikationen
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Archives of surg ...
- Av lärosätet
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Uppsala universitet
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Göteborgs universitet