Perinatal famine is associated with excess risk of proliferative retinopathy in patients with type 2 diabetes

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Sökning: onr:"swepub:oai:DiVA.org:umu-185545" > Perinatal famine is...

1 av 1
Föregående post
Nästa post
Till träfflistan

Perinatal famine is associated with excess risk of proliferative retinopathy in patients with type 2 diabetes

Fedotkina, Olena (författare): Department of Clinical Science, Center for Diabetes Research, University of Bergen, Bergen, Norway

Luk, Andrea (författare): Hong Kong Institute of Diabetes and Obesity, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong

Jain, Ruchi (författare): Lund University,Lunds universitet,Öcellsfysiologi,Forskargrupper vid Lunds universitet,Islet cell physiology,Lund University Research Groups,Skåne University Hospital

visa fler...

Prasad, Rashmi B (författare): Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Skåne University Hospital

Shungin, Dmitry (författare): Umeå University,Umeå universitet,Institutionen för odontologi,Broad Institute of Harvard and MIT, MA, Cambridge, United States

Simó-Servat, Olga (författare): Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERDEM, Barcelona, Spain,Autonomous University of Barcelona

Özgümüs, Türküler (författare): Department of Clinical Science, Center for Diabetes Research, University of Bergen, Bergen, Norway

Cherviakova, Liubov (författare): Chernihiv Regional Hospital, Chernihiv, Ukraine

Khalimon, Nadiya (författare): City Hospital No 2, Chernihiv, Ukraine

Svietleisha, Tetiana (författare): City Hospital No 1, Chernihiv, Ukraine

Buldenko, Tetiana (författare): Department of Health Care of Chernihiv Regional State Administration, Chernihiv, Ukraine

Kravchenko, Victor (författare): Komisarenko Institute of Endocrinology and Metabolism, Kyiv, Ukraine,V. P. Komisarenko Institute of Endocrinology and Metabolism of the Ukraine Academy of Medical Sciences

Hernández, Cristina (författare): Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERDEM, Barcelona, Spain,Autonomous University of Barcelona

Jain, Deepak (författare): Lund University,Lunds universitet,Antigen presentation,Forskargrupper vid Lunds universitet,Medicinsk proteinvetenskap,Antigen Presentation,Lund University Research Groups,Medical Protein Science,Skåne University Hospital

Simo, Rafael (författare): Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERDEM, Barcelona, Spain,Autonomous University of Barcelona

Artner, Isabella (författare): Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Endokrin Celldifferentiering,Forskargrupper vid Lunds universitet,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine,Endocrine Cell Differentiation and Function,Lund University Research Groups,Skåne University Hospital

Nilsson, Peter M (författare): Lund University,Lunds universitet,Enheten för medicinens historia,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,History of Medicine,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital

Khalangot, Mykola D. (författare): Komisarenko Institute of Endocrinology and Metabolism, Kyiv, Ukraine; Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine,V. P. Komisarenko Institute of Endocrinology and Metabolism of the Ukraine Academy of Medical Sciences

Vaiserman, Alexander M. (författare): Laboratory of Epigenetics, Chebotarev Institute of Gerontology, Kyiv, Ukraine,Dmitry F. Chebotarev Institute of Gerontology of the National Academy of Medical Sciences of Ukraine

Chan, Juliana (författare): Hong Kong Institute of Diabetes and Obesity, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong

Vaag, Allan (författare): Steno Diabetes Center Copenhagen, Copenhagen, Denmark

Lyssenko, Valeriya (författare): Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Skåne University Hospital,University of Bergen

visa färre...

(creator_code:org_t)

2021-06-24
2022
Engelska.
Ingår i: Acta Ophthalmologica. - : John Wiley & Sons. - 1755-375X .- 1755-3768. ; 100:2, s. e539-e545

Relaterad länk:: http://dx.doi.org/10...; visa fler...; https://urn.kb.se/re...; https://doi.org/10.1...; https://lup.lub.lu.s...; visa färre...

Tidskriftsartikel (refereegranskat)

Abstract Ämnesord

Stäng

Purpose: Intrauterine undernutrition is associated with increased risk of type 2 diabetes. Children born premature or small for gestational age were reported to have abnormal retinal vascularization. However, whether intrauterine famine act as a trigger for diabetes complications, including retinopathy, is unknown. The aim of the current study was to evaluate long-term effects of perinatal famine on the risk of proliferative diabetic retinopathy (PDR).Methods: We studied the risk for PDR among type 2 diabetes patients exposed to perinatal famine in two independent cohorts: the Ukrainian National Diabetes Registry (UNDR) and the Hong Kong Diabetes Registry (HKDR). We analysed individuals born during the Great Famine (the Holodomor, 1932–1933) and the WWII (1941–1945) famine in 101 095 (3601 had PDR) UNDR participants. Among 3021 (251 had PDR) HKDR participants, we studied type 2 diabetes patients exposed to perinatal famine during the WWII Japanese invasion in 1942–1945.Results: During the Holodomor and WWII, perinatal famine was associated with a 1.76-fold (p = 0.019) and 3.02-fold (p = 0.001) increased risk of severe PDR in the UNDR. The risk for PDR was 1.66-fold elevated among individuals born in 1942 in the HKDR (p < 0.05). The associations between perinatal famine and PDR remained statistically significant after corrections for HbA1c in available 18 507 UNDR (padditive interaction < 0.001) and in 3021 HKDR type 2 diabetes patients (p < 0.05).Conclusion: In conclusion, type 2 diabetes patients, exposed to perinatal famine, have increased risk of PDR compared to those without perinatal famine exposure. Further studies are needed to understand the underlying mechanisms and to extend this finding to other diabetes complications.

Hitta via bibliotek

Acta Ophthalmologica (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

1 av 1
Föregående post
Nästa post
Till träfflistan

Hitta mer i SwePub

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Endokrinologi oc ...

Artiklar i publikationen: Acta Ophthalmolo ...

Av lärosätet: Umeå universitet; Lunds universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se

Perinatal famine is associated with excess risk of proliferative retinopathy in patients with type 2 diabetes

Ämnesord

Nyckelord

Publikations- och innehållstyp

Hitta via bibliotek

Till lärosätets databas

Hitta mer i SwePub

Sök utanför SwePub