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Mediterranean diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort

Molina-Montes, Esther (författare)
CIBER Epidemiology and Public Health (CIBERESP),Andalusian School Of Public Health (EASP),Spanish National Cancer Research Center (CNIO)
Sánchez, María José (författare)
Andalusian School Of Public Health (EASP),CIBER Epidemiology and Public Health (CIBERESP)
Buckland, Genevieve (författare)
Catalan Institute of Oncology
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Bueno-De-Mesquita, H. B. (författare)
National Institute for Public Health and the Environment (RIVM),University Medical Center Utrecht,Imperial College London,University of Malaya,German Institute of Human Nutrition
Weiderpass, Elisabete (författare)
Karolinska Institutet,Karolinska Institute,Folkhälsan Research Center,Cancer Registry of Norway, Institute of Population-Based Cancer Research,UiT The Arctic University of Norway, Tromsø
Amiano, Pilar (författare)
CIBER Epidemiology and Public Health (CIBERESP),Biodonostia Health Research Institute
Wark, Petra A. (författare)
Imperial College London,Versailles Saint-Quentin-en-Yvelines University,Stabilite genetique et oncogenese
Kühn, Tilman (författare)
German Cancer Research Centre
Katzke, Verena (författare)
National Institute for Public Health and the Environment (RIVM)
Huerta, José María (författare)
CIBER Epidemiology and Public Health (CIBERESP),Murcia Regional Health Council
Ardanaz, Eva (författare)
CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA)
Quirós, José Ramón (författare)
Public Health Directorate
Affret, Aurélie (författare)
Versailles Saint-Quentin-en-Yvelines University,Stabilite genetique et oncogenese,Imperial College London
His, Mathilde (författare)
Stabilite genetique et oncogenese,Versailles Saint-Quentin-en-Yvelines University
Boutron-Ruault, Marie Christine (författare)
Versailles Saint-Quentin-en-Yvelines University,Stabilite genetique et oncogenese
Peeters, Petra H. (författare)
University Medical Center Utrecht,Imperial College London
Ye, Weimin (författare)
Karolinska Institutet,Umeå universitet,Umeå University,Enheten för biobanksforskning,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Sund, Malin (författare)
Umeå universitet,Umeå University,Karolinska Institute,Enheten för biobanksforskning,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Boeing, Heiner (författare)
German Institute of Human Nutrition
Iqbal, Khalid (författare)
German Institute of Human Nutrition
Ohlsson, Bodil (författare)
Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital
Sonestedt, Emily (författare)
Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Nutritionsepidemiologi,Diabetes - Cardiovascular Disease,Lund University Research Groups,Nutrition Epidemiology
Tjønneland, Anne (författare)
Danish Cancer Society
Petersen, Kristina E.N. (författare)
Danish Cancer Society
Travis, Ruth C. (författare)
University of Oxford
Skeie, Guri (författare)
UiT The Arctic University of Norway, Tromsø
Agnoli, Claudia (författare)
Istituto Nazionale dei Tumori
Panico, Salvatore (författare)
University of Naples Federico II
Palli, Domenico (författare)
Cancer Research and Prevention Institute (ISPO)
Tumino, Rosario (författare)
Civic and M.P Arezzo Hospital
Sacerdote, Carlotta (författare)
Citta' della Salute e della Scienza Hospital-University of Turin
Freisling, Heinz (författare)
International Agency for Research on Cancer, World Health Organization
Huybrechts, Inge (författare)
International Agency for Research on Cancer, World Health Organization
Overvad, Kim (författare)
Aarhus University
Trichopoulou, Antonia (författare)
National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens
Bamia, Christina (författare)
Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens
Vasilopoulou, Effie (författare)
National and Kapodistrian University of Athens
Wareham, Nick (författare)
MRC Human Nutrition Research
Khaw, Kay Tee (författare)
University of Cambridge
Cross, Amanda J. (författare)
Imperial College London
Ward, Heather A. (författare)
Imperial College London
Riboli, Elio (författare)
Imperial College London
Duell, Eric J. (författare)
Catalan Institute of Oncology
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 (creator_code:org_t)
2017-02-07
2017
Engelska 10 s.
Ingår i: British Journal of Cancer. - : Springer Science and Business Media LLC. - 0007-0920 .- 1532-1827. ; 116:6, s. 811-820
Relaterad länk:
http://dx.doi.org/10... (free)
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https://www.nature.c...
https://lup.lub.lu.s...
https://doi.org/10.1...
https://urn.kb.se/re...
http://kipublication...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background:The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.Methods:Over half a million participants from 10 European countries were followed up for over 11 years, after which 865 newly diagnosed exocrine pancreatic cancer cases were identified. Adherence to the MD was estimated through an adapted score without the alcohol component (arMED) to discount alcohol-related harmful effects. Cox proportional hazards regression models, stratified by age, sex and centre, and adjusted for energy intake, body mass index, smoking status, alcohol intake and diabetes status at recruitment, were used to estimate hazard ratios (HRs) associated with pancreatic cancer and their corresponding 95% confidence intervals (CIs).Results:Adherence to the arMED score was not associated with risk of pancreatic cancer (HR high vs low adherence=0.99; 95% CI: 0.77-1.26, and HR per increments of two units in adherence to arMED=1.00; 95% CI: 0.94-1.06). There was no convincing evidence for heterogeneity by smoking status, body mass index, diabetes or European region. There was also no evidence of significant associations in analyses involving microscopically confirmed cases, plausible reporters of energy intake or other definitions of the MD pattern.Conclusions:A high adherence to the MD is not associated with pancreatic cancer risk in the EPIC study.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Näringslära (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nutrition and Dietetics (hsv//eng)

Nyckelord

cohort study
Mediterranean diet
pancreatic cancer
Mediterranean diet

Publikations- och innehållstyp

art (ämneskategori)
ref (ämneskategori)

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