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Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts

Jelenkovic, A (author)
Department of Social Research, University of Helsinki, Helsinki, Finland; Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, Leioa, Spain
Sund, R (author)
Hur, YM (author)
show more...
Yokoyama, Y (author)
Hjelmborg, JVB (author)
Moller, S (author)
Honda, C (author)
Magnusson, PKE (author)
Karolinska Institutet
Pedersen, NL (author)
Karolinska Institutet
Ooki, S (author)
Aaltonen, S (author)
Stazi, MA (author)
Fagnani, C (author)
D'Ippolito, C (author)
Freitas, DL (author)
Maia, JA (author)
Ji, FL (author)
Ning, F (author)
Pang, ZC (author)
Rebato, E (author)
Busjahn, A (author)
Kandler, C (author)
Saudino, KJ (author)
Jang, KL (author)
Cozen, W (author)
Hwang, AE (author)
Mack, TM (author)
Gao, WJ (author)
Yu, CQ (author)
Li, LM (author)
Corley, RP (author)
Huibregtse, BM (author)
Derom, CA (author)
Vlietinck, RF (author)
Karolinska Institutet
Loos, RJF (author)
Heikkila, K (author)
Wardle, J (author)
Llewellyn, CH (author)
Fisher, A (author)
McAdams, TA (author)
Tuvblad, Catherine, 1968- (author)
Örebro universitet,Institutionen för juridik, psykologi och socialt arbete
Gregory, AM (author)
He, MG (author)
Ding, XH (author)
Bjerregaard-Andersen, M (author)
Beck-Nielsen, H (author)
Sodemann, M (author)
Tarnoki, AD (author)
Tarnoki, DL (author)
Knafo-Noam, A (author)
Mankuta, D (author)
Abramson, L (author)
Burt, SA (author)
Klump, KL (author)
Silberg, JL (author)
Eaves, LJ (author)
Maes, HH (author)
Krueger, RF (author)
McGue, M (author)
Pahlen, S (author)
Gatz, M (author)
Butler, DA (author)
Bartels, M (author)
van Beijsterveldt, TCEM (author)
Craig, JM (author)
Saffery, R (author)
Dubois, L (author)
Boivin, M (author)
Brendgen, M (author)
Dionne, G (author)
Vitaro, F (author)
Martin, NG (author)
Medland, SE (author)
Montgomery, GW (author)
Swan, GE (author)
Krasnow, R (author)
Tynelius, P (author)
Karolinska Institutet
Lichtenstein, P (author)
Karolinska Institutet
Haworth, CMA (author)
Plomin, R (author)
Bayasgalan, G (author)
Narandalai, D (author)
Harden, KP (author)
Tucker-Drob, EM (author)
Spector, T (author)
Mangino, M (author)
Lachance, G (author)
Baker, LA (author)
Tuvblad, C (author)
Duncan, GE (author)
Buchwald, D (author)
Willemsen, G (author)
Skytthe, A (author)
Kyvik, KO (author)
Christensen, K (author)
Oncel, SY (author)
Aliev, F (author)
Rasmussen, F (author)
Karolinska Institutet
Goldberg, JH (author)
Sorensen, TIA (author)
Boomsma, DI (author)
Kaprio, J (author)
Silventoinen, K (author)
Department of Social Research, University of Helsinki, Helsinki, Finland; Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan
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 (creator_code:org_t)
2016-06-23
2016
English.
In: Scientific reports. - London, United Kingdom : Springer Science and Business Media LLC. - 2045-2322. ; 6, s. 28496-
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Height variation is known to be determined by both genetic and environmental factors, but a systematic description of how their influences differ by sex, age and global regions is lacking. We conducted an individual-based pooled analysis of 45 twin cohorts from 20 countries, including 180,520 paired measurements at ages 1–19 years. The proportion of height variation explained by shared environmental factors was greatest in early childhood, but these effects remained present until early adulthood. Accordingly, the relative genetic contribution increased with age and was greatest in adolescence (up to 0.83 in boys and 0.76 in girls). Comparing geographic-cultural regions (Europe, North-America and Australia and East-Asia), genetic variance was greatest in North-America and Australia and lowest in East-Asia, but the relative proportion of genetic variation was roughly similar across these regions. Our findings provide further insights into height variation during childhood and adolescence in populations representing different ethnicities and exposed to different environments.

Subject headings

NATURVETENSKAP  -- Biologi -- Evolutionsbiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Evolutionary Biology (hsv//eng)
NATURVETENSKAP  -- Biologi -- Genetik (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Genetics (hsv//eng)

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ref (subject category)
art (subject category)

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By the author/editor
Jelenkovic, A
Sund, R
Hur, YM
Yokoyama, Y
Hjelmborg, JVB
Moller, S
show more...
Honda, C
Magnusson, PKE
Pedersen, NL
Ooki, S
Aaltonen, S
Stazi, MA
Fagnani, C
D'Ippolito, C
Freitas, DL
Maia, JA
Ji, FL
Ning, F
Pang, ZC
Rebato, E
Busjahn, A
Kandler, C
Saudino, KJ
Jang, KL
Cozen, W
Hwang, AE
Mack, TM
Gao, WJ
Yu, CQ
Li, LM
Corley, RP
Huibregtse, BM
Derom, CA
Vlietinck, RF
Loos, RJF
Heikkila, K
Wardle, J
Llewellyn, CH
Fisher, A
McAdams, TA
Tuvblad, Catheri ...
Gregory, AM
He, MG
Ding, XH
Bjerregaard-Ande ...
Beck-Nielsen, H
Sodemann, M
Tarnoki, AD
Tarnoki, DL
Knafo-Noam, A
Mankuta, D
Abramson, L
Burt, SA
Klump, KL
Silberg, JL
Eaves, LJ
Maes, HH
Krueger, RF
McGue, M
Pahlen, S
Gatz, M
Butler, DA
Bartels, M
van Beijsterveld ...
Craig, JM
Saffery, R
Dubois, L
Boivin, M
Brendgen, M
Dionne, G
Vitaro, F
Martin, NG
Medland, SE
Montgomery, GW
Swan, GE
Krasnow, R
Tynelius, P
Lichtenstein, P
Haworth, CMA
Plomin, R
Bayasgalan, G
Narandalai, D
Harden, KP
Tucker-Drob, EM
Spector, T
Mangino, M
Lachance, G
Baker, LA
Tuvblad, C
Duncan, GE
Buchwald, D
Willemsen, G
Skytthe, A
Kyvik, KO
Christensen, K
Oncel, SY
Aliev, F
Rasmussen, F
Goldberg, JH
Sorensen, TIA
Boomsma, DI
Kaprio, J
Silventoinen, K
show less...
About the subject
NATURAL SCIENCES
NATURAL SCIENCES
and Biological Scien ...
and Evolutionary Bio ...
NATURAL SCIENCES
NATURAL SCIENCES
and Biological Scien ...
and Genetics
Articles in the publication
Scientific repor ...
By the university
Karolinska Institutet
Örebro University

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