Costs and resource utilization for diagnosis and treatment during the initial year in a European inflammatory bowel disease inception cohort: an ECCO-EpiCom Study

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Costs and resource utilization for diagnosis and treatment during the initial year in a European inflammatory bowel disease inception cohort : an ECCO-EpiCom Study

Burisch, Johan (författare): Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark

Vardi, Hillel (författare): Department of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel

Pedersen, Natalia (författare): Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark

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Brinar, Marko (författare): Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia

Cukovic-Cavka, Silvja (författare): Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia

Kaimakliotis, Ioannis (författare): Private Practice, Nicosia, Cyprus

Duricova, Dana (författare): IBD Center ISCARE, Charles University, Prague, Czech Republic

Bortlik, Martin (författare): IBD Center ISCARE, Charles University, Prague, Czech Republic

Shonová, Olga (författare): Department of Gastroenterology, Hospital Ceske Budejovice, Ceske Budejovice, Czech Republic

Vind, Ida (författare): Department of Medicine, Amager Hospital, Amager, Denmark

Avnstrøm, Søren (författare): Department of Medicine, Amager Hospital, Amager, Denmark

Thorsgaard, Niels (författare): Department of Medicine, Herning Central Hospital, Herning, Denmark

Krabbe, Susanne (författare): Medical Department, Viborg Regional Hospital, Viborg, Denmark

Andersen, Vibeke (författare): Medical Department, Viborg Regional Hospital, Viborg, Denmark; Organ Center, Hospital of Southern Jutland, Aabenraa, Denmark; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark

Dahlerup, Jens F (författare): Department of Medicine V (Hepatology and Gastroenterology), Aarhus University Hospital, Arhus, Denmark

Kjeldsen, Jens (författare): Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark

Salupere, Riina (författare): Division of Endocrinology and Gastroenterology, Tartu University Hospital, Tartu, Estonia

Olsen, Jónger (författare): Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands

Nielsen, Kári R (författare): Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands

Manninen, Pia (författare): Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland

Collin, Pekka (författare): Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland

Katsanos, Konstantinnos H (författare): First Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece

Tsianos, Epameinondas V (författare): First Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece

Ladefoged, Karin (författare): Medical Department, Dronning Ingrids Hospital, Nuuk, Greenland

Lakatos, Laszlo (författare): First Department of Medicine, Semmelweis University, Budapest, Hungary

Bailey, Yvonne (författare): Department of Gastroenterology, Adelaide and Meath Hospital, TCD, Dublin, Ireland

OʼMorain, Colm (författare): Department of Gastroenterology, Adelaide and Meath Hospital, TCD, Dublin, Ireland

Schwartz, Doron (författare): Department of Gastroenterology and Hepatology, Soroka Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel

Lupinacci, Guido (författare): U.O. di Gastroenterologia e Endoscopia Digestiva, Az.Ospedaliera Ospedale Maggiore di Crema, Crema, Italy; EpiCom Northern Italy centre based in Crema and Cremona, Firenze, Forli, Padova and Reggio Emilia, Italy

De Padova, Angelo (författare): EpiCom Northern Italy centre based in Crema and Cremona, Firenze, Forli, Padova and Reggio Emilia, Italy; U.O. Gastroenterologia ed Endoscopia Digestiva, Ospedale Morgagni, Pierantoni, Forli, Italy

Jonaitis, Laimas (författare): Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania

Kupcinskas, Limas (författare): Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania

Turcan, Svetlana (författare): Department of Gastroenterology, State University of Medicine and Pharmacy of the Republic of Moldova, Chisinau, Republic of Moldova

Barros, Louisa (författare): Department of Medicine, Hospital de Vale de Sousa, Porto, Portugal

Magro, Fernando (författare): Department of Gastroenterology, Hospital de Sao Joao, Porto, Portugal; Institute of Pharmacology and Therapeutics, Oporto Medical School, Porto, Portugal; Institute for molecular and cell biology, University of Porto, Porto, Portugal

Lazar, Daniela (författare): Clinic of Gastroenterology, University of Medicine "Victor Babes," Timisoara, Romania

Goldis, Adrian (författare): Clinic of Gastroenterology, University of Medicine "Victor Babes," Timisoara, Romania

Nikulina, Inna (författare): Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russia

Belousova, Elena (författare): Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russia

Fernandez, Alberto (författare): Gastroenterology Department, POVISA Hospital, Vigo, Spain

Pineda, Juan R (författare): Gastroenterology Department, Complexo Hospitalario Universitario de Vigo, Vigo, Spain

Almer, Sven (författare): Karolinska Institutet

Halfvarson, Jonas, 1970- (författare): Örebro universitet,Institutionen för läkarutbildning,Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden; School of Health and Medical Sciences, Örebro University, Örebro, Sweden

Tsai, Her-Hsin (författare): Hull and East Yorkshire NHS Trust and Hull and York Medical School, Hull Royal Infirmary, Hull, United Kingdom

Sebastian, Shaji (författare): Hull and East Yorkshire NHS Trust and Hull and York Medical School, Hull Royal Infirmary, Hull, United Kingdom

Friger, Michael (författare): Department of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel

Greenberg, Dan (författare): Department of Health Systems Management, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel; Guilford Glazer Faculty of Business and Management, Ben Gurion University of the Negev, Beer Sheva, Israel

Lakatos, Peter L (författare): First Department of Medicine, Semmelweis University, Budapest, Hungary

Langholz, Ebbe (författare): Department of Medical Gastroenterology, Gentofte Hospital, Copenhagen, Denmark

Odes, Selwyn (författare): Department of Gastroenterology and Hepatology, Soroka Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel

Munkholm, Pia (författare): Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark

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(creator_code:org_t)

2015
2015
Engelska.
Ingår i: Inflammatory Bowel Diseases. - 1078-0998 .- 1536-4844. ; 21:1, s. 121-131

Relaterad länk:: https://urn.kb.se/re...; visa fler...; https://doi.org/10.1...; http://kipublication...; visa färre...

Tidskriftsartikel (refereegranskat)

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BACKGROUND: No direct comparison of health care cost in patients with inflammatory bowel disease across the European continent exists. The aim of this study was to assess the costs of investigations and treatment for diagnostics and during the first year after diagnosis in Europe.METHODS: The EpiCom cohort is a prospective population-based inception cohort of unselected inflammatory bowel disease patients from 31 Western and Eastern European centers. Patients were followed every third month from diagnosis, and clinical data regarding treatment and investigations were collected. Costs were calculated in euros (&OV0556;) using the Danish Health Costs Register.RESULTS: One thousand three hundred sixty-seven patients were followed, 710 with ulcerative colitis, 509 with Crohn's disease, and 148 with inflammatory bowel disease unclassified. Total expenditure for the cohort was &OV0556;5,408,174 (investigations: &OV0556;2,042,990 [38%], surgery: &OV0556;1,427,648 [26%], biologicals: &OV0556;781,089 [14%], and standard treatment: &OV0556;1,156,520 [22%)]). Mean crude expenditure per patient in Western Europe (Eastern Europe) with Crohn's disease: investigations &OV0556;1803 (&OV0556;2160) (P = 0.44), surgery &OV0556;11,489 (&OV0556;13,973) (P = 0.14), standard treatment &OV0556;1027 (&OV0556;824) (P = 0.51), and biologicals &OV0556;7376 (&OV0556;8307) (P = 0.31). Mean crude expenditure per patient in Western Europe (Eastern Europe) with ulcerative colitis: investigations &OV0556;1189 (&OV0556;1518) (P < 0.01), surgery &OV0556;18,414 (&OV0556;12,395) (P = 0.18), standard treatment &OV0556;896 (&OV0556;798) (P < 0.05), and biologicals &OV0556;5681 (&OV0556;72) (P = 0.51).CONCLUSIONS: In this population-based unselected cohort, costs during the first year of disease were mainly incurred by investigative procedures and surgeries. However, biologicals accounted for >15% of costs. Long-term follow-up of the cohort is needed to assess the cost-effectiveness of biological agents.

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Av författaren/redakt...: Burisch, Johan; Vardi, Hillel; Pedersen, Natali ...; Brinar, Marko; Cukovic-Cavka, S ...; Kaimakliotis, Io ...; visa fler...; Duricova, Dana; Bortlik, Martin; Shonová, Olga; Vind, Ida; Avnstrøm, Søren; Thorsgaard, Niel ...; Krabbe, Susanne; Andersen, Vibeke; Dahlerup, Jens F; Kjeldsen, Jens; Salupere, Riina; Olsen, Jónger; Nielsen, Kári R; Manninen, Pia; Collin, Pekka; Katsanos, Konsta ...; Tsianos, Epamein ...; Ladefoged, Karin; Lakatos, Laszlo; Bailey, Yvonne; OʼMorain, Colm; Schwartz, Doron; Lupinacci, Guido; De Padova, Angel ...; Jonaitis, Laimas; Kupcinskas, Lima ...; Turcan, Svetlana; Barros, Louisa; Magro, Fernando; Lazar, Daniela; Goldis, Adrian; Nikulina, Inna; Belousova, Elena; Fernandez, Alber ...; Pineda, Juan R; Almer, Sven; Halfvarson, Jona ...; Tsai, Her-Hsin; Sebastian, Shaji; Friger, Michael; Greenberg, Dan; Lakatos, Peter L; Langholz, Ebbe; Odes, Selwyn; Munkholm, Pia; visa färre...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Gastroenterologi

Artiklar i publikationen: Inflammatory Bow ...

Av lärosätet: Örebro universitet; Karolinska Institutet

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Costs and resource utilization for diagnosis and treatment during the initial year in a European inflammatory bowel disease inception cohort : an ECCO-EpiCom Study

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