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Scintigraphic asses...
Scintigraphic assessment of slow transit constipation with special reference to right- or left-sided colonic delay
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- Lundin, Erik (författare)
- Uppsala universitet,Kolorektalkirurgi
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- Karlbom, Urban (författare)
- Uppsala universitet,Kolorektalkirurgi
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Westlin, Jan-Erik (författare)
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Kairemo, Kalevi (författare)
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- Jung, Bo (författare)
- Uppsala universitet,Institutionen för kirurgiska vetenskaper
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Husin, Stig (författare)
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- Påhlman, Lars (författare)
- Uppsala universitet,Kolorektalkirurgi
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- Graf, Wilhelm (författare)
- Uppsala universitet,Kolorektalkirurgi
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(creator_code:org_t)
- Wiley, 2004
- 2004
- Engelska.
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Ingår i: Colorectal Disease. - : Wiley. - 1462-8910 .- 1463-1318. ; 6:6, s. 499-505
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- OBJECTIVE: Subtotal colectomy and ileorectal anastomosis for slow transit constipation has several side-effects. The motor abnormality in some patients may be segmental which could motivate a limited resection of the colon. Therefore a diagnostic tool to identify a segmental colonic motor dysfunction is needed. The aim of this study was to evaluate a scintigraphic method to assess colonic transit with special reference to right- or left-sided delay. METHODS: Twenty-three constipated patients (19 women, mean age 50 years) with slow colonic transit on radio-opaque marker studies and 13 healthy individuals (11 women, mean age 46 years) were studied. All subjects were examined with oral (111)Indium-DTPA scintigraphy. The scintigraphic results for patients and controls were presented as geometric centre of radioactivity and percent activity over time in the right, the left and the recto-sigmoid colon. The inter-observer variation in the interpretation of the scans was also evaluated. RESULTS: There was no difference in transit time between the groups of patients and controls in the right colon whereas the patients had a significant delay in the left colon (P < 0.05). Two patients had a marked delay in the right colon followed by relatively rapid transit in the left colon. The inter-observer correlation was good comparing the right, the left and the recto-sigmoid colon (r = 0.58-0.98, P < 0.01-0.001). CONCLUSION: The results indicate that colonic scintigraphy with oral (111)Indium-DTPA may help to select patients for a left or, in a few cases, a right hemicolectomy for slow transit constipation.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Adult
- Aged
- Case-Control Studies
- Colon/physiology
- Comparative Study
- Constipation/physiopathology/*radionuclide imaging/surgery
- Female
- Gastrointestinal Transit/*physiology
- History; Medieval
- Humans
- Indium Radioisotopes/*diagnostic use
- Male
- Manometry
- Middle Aged
- Observer Variation
- Probability
- Prospective Studies
- Reference Values
- Sensitivity and Specificity
- Severity of Illness Index
- Statistics; Nonparametric
- Time Factors
- Surgery
- Kirurgi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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