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Circulating insulin...
Circulating insulin-like growth factor I in relation to melanoma risk in the European prospective investigation into cancer and nutrition
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- Bradbury, Kathryn E. (författare)
- University of Oxford,University of Auckland
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- Appleby, Paul N. (författare)
- University of Oxford
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- Tipper, Sarah J. (författare)
- University of Oxford
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- Travis, Ruth C. (författare)
- University of Oxford
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- Allen, Naomi E (författare)
- University of Oxford
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- Kvaskoff, Marina (författare)
- University of Paris-Saclay,Stabilite genetique et oncogenese
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- Overvad, Kim (författare)
- Aarhus University
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- Tjønneland, Anne (författare)
- Danish Cancer Society
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- Halkjaer, Jytte (författare)
- Danish Cancer Society
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- Cervenka, Iris (författare)
- University of Paris-Saclay,Stabilite genetique et oncogenese
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- Mahamat-Saleh, Yahya (författare)
- University of Paris-Saclay,Stabilite genetique et oncogenese
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- Bonnet, Fabrice (författare)
- Stabilite genetique et oncogenese,University of Rennes I,University of Paris-Saclay
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- Kaaks, Rudolf (författare)
- German Cancer Research Centre
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- Fortner, Renée T. (författare)
- German Cancer Research Centre
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- Boeing, Heiner (författare)
- German Institute of Human Nutrition
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- Trichopoulou, Antonia (författare)
- Hellenic Health Foundation, Athens
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- La Vecchia, Carlo (författare)
- University of Milan,Hellenic Health Foundation, Athens
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- Stratigos, Alexander J. (författare)
- Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens
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- Palli, Domenico (författare)
- Cancer Research and Prevention Institute (ISPO)
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- Grioni, Sara (författare)
- Istituto Nazionale dei Tumori
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- Matullo, Giuseppe (författare)
- University of Turin
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- Panico, Salvatore (författare)
- University of Naples Federico II
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- Tumino, Rosario (författare)
- Civic and M.P Arezzo Hospital
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- Peeters, Petra H. (författare)
- University Medical Center Utrecht
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- Bueno-de-Mesquita, H Bas (författare)
- Imperial College London,University of Malaya,National Institute for Public Health and the Environment (RIVM)
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- Ghiasvand, Reza (författare)
- University of Oslo
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- Veierød, Marit B. (författare)
- University of Oslo
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- Weiderpass, Elisabete (författare)
- Karolinska Institutet,Karolinska Institute,Cancer Registry of Norway, Institute of Population-Based Cancer Research,University of Helsinki,UiT The Arctic University of Norway, Tromsø
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- Bonet, Catalina (författare)
- Bellvitge University Hospital-IDIBELL
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- Molina, Elena (författare)
- CIBER Epidemiology and Public Health (CIBERESP),University of Granada
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- Huerta, José M. (författare)
- Murcia Regional Health Council,CIBER Epidemiology and Public Health (CIBERESP)
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- Larrañaga, Nerea (författare)
- CIBER Epidemiology and Public Health (CIBERESP)
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- Barricarte, Aurelio (författare)
- Health Research Institute of Navarra (IDISNA),CIBER Epidemiology and Public Health (CIBERESP)
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- Merino, Susana (författare)
- Public Health Directorate
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- Isaksson, Karolin (författare)
- Lund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lunds Melanomstudiegrupp,Forskargrupper vid Lunds universitet,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Melanoma Study Group,Lund University Research Groups,Skåne University Hospital
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- Stocks, Tanja (författare)
- Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups
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- Ljuslinder, Ingrid, 1968- (författare)
- Norrland University Hospital
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- Hemmingsson, Oskar, 1975- (författare)
- Umeå University,Umeå universitet,Kirurgi
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- Wareham, Nick (författare)
- University of Cambridge
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- Khaw, Kay-Tee (författare)
- University of Cambridge
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- Gunter, Marc J. (författare)
- International Agency for Research on Cancer, World Health Organization
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- Rinaldi, Sabina (författare)
- International Agency for Research on Cancer, World Health Organization
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- Tsilidis, Konstantinos K. (författare)
- Imperial College London,University of Ioannina
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- Aune, Dagfinn (författare)
- Oslo university hospital,Bjørknes University College,Imperial College London
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- Riboli, Elio (författare)
- Imperial College London
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- Key, Timothy J. (författare)
- University of Oxford
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(creator_code:org_t)
- 2018-12-07
- 2019
- Engelska.
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Ingår i: International Journal of Cancer. - : John Wiley & Sons. - 0020-7136 .- 1097-0215. ; 144:5, s. 957-966
- Relaterad länk:
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https://doi.org/10.1...
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visa fler...
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https://umu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Insulin-like growth factor-I (IGF-I) regulates cell proliferation and apoptosis, and is thought to play a role in tumour development. Previous prospective studies have shown that higher circulating concentrations of IGF-I are associated with a higher risk of cancers at specific sites, including breast and prostate. No prospective study has examined the association between circulating IGF-I concentrations and melanoma risk. A nested case-control study of 1,221 melanoma cases and 1,221 controls was performed in the European Prospective Investigation into Cancer and Nutrition cohort, a prospective cohort of 520,000 participants recruited from 10 European countries. Conditional logistic regression was used to estimate odds ratios (ORs) for incident melanoma in relation to circulating IGF-I concentrations, measured by immunoassay. Analyses were conditioned on the matching factors and further adjusted for age at blood collection, education, height, BMI, smoking status, alcohol intake, marital status, physical activity and in women only, use of menopausal hormone therapy. There was no significant association between circulating IGF-I concentration and melanoma risk (OR for highest vs lowest fifth = 0.93 [95% confidence interval [CI]: 0.71 to 1.22]). There was no significant heterogeneity in the association between IGF-I concentrations and melanoma risk when subdivided by gender, age at blood collection, BMI, height, age at diagnosis, time between blood collection and diagnosis, or by anatomical site or histological subtype of the tumour (Pheterogeneity≥0.078). We found no evidence for an association between circulating concentrations of IGF-I measured in adulthood and the risk of melanoma.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- EPIC
- biomarker
- height
- insulin-like growth factor I
- melanoma
- prospective studies
- biomarker
- EPIC
- height
- insulin-like growth factor I
- melanoma
- prospective studies
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Bradbury, Kathry ...
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Appleby, Paul N.
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Tipper, Sarah J.
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Travis, Ruth C.
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Allen, Naomi E
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Kvaskoff, Marina
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visa fler...
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Overvad, Kim
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Tjønneland, Anne
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Halkjaer, Jytte
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Cervenka, Iris
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Mahamat-Saleh, Y ...
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Bonnet, Fabrice
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Kaaks, Rudolf
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Fortner, Renée T ...
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Boeing, Heiner
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Trichopoulou, An ...
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La Vecchia, Carl ...
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Stratigos, Alexa ...
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Palli, Domenico
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Grioni, Sara
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Matullo, Giusepp ...
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Panico, Salvator ...
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Tumino, Rosario
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Peeters, Petra H ...
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Bueno-de-Mesquit ...
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Ghiasvand, Reza
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Veierød, Marit B ...
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Weiderpass, Elis ...
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Bonet, Catalina
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Molina, Elena
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Huerta, José M.
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Larrañaga, Nerea
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Barricarte, Aure ...
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Merino, Susana
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Isaksson, Karoli ...
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Stocks, Tanja
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Ljuslinder, Ingr ...
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Hemmingsson, Osk ...
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Wareham, Nick
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Khaw, Kay-Tee
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Gunter, Marc J.
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Rinaldi, Sabina
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Tsilidis, Konsta ...
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Aune, Dagfinn
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Riboli, Elio
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Key, Timothy J.
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
- Artiklar i publikationen
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International Jo ...
- Av lärosätet
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Umeå universitet
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Lunds universitet
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Karolinska Institutet