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Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.
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- McLeod, Olga (author)
- Karolinska Institutet
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- Silveira, Angela (author)
- Karolinska Institutet
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- Nordin Fredrikson, Gunilla (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups
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- Baldassarre, Damiano (author)
- Veglia, Fabrizio (author)
- Larsson, Malin (author)
- Kauhanen, Jussi (author)
- Rauramaa, Rainer (author)
- Smit, Andries J (author)
- Mannarino, Elmo (author)
- Giral, Philippe (author)
- Humphries, Steve E (author)
- Tremoli, Elena (author)
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- (creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
- In: Atherosclerosis. - : Elsevier BV. - 1879-1484 .- 0021-9150. ; 232:1, s. 242-248
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Experimental studies have suggested that autoimmunity is involved in atherosclerosis and provided evidence that both protective and pro-atherogenic immune responses exist. This concept has received support from small clinical studies implicating autoantibodies directed against apolipoprotein B-100 (apoB-100) in human atherosclerosis. We examined circulating autoantibodies directed against native and malondialdehyde (MDA)-modified epitope p210 of apoB-100 (IgG-p210nat and IgM-p210MDA) in relation to early atherosclerosis in a large, European longitudinal cohort study of healthy high-risk individuals.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
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- art (subject category)
- ref (subject category)
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- McLeod, Olga
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- Sennblad, Bengt
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- Larsson, Malin
- Leander, Karin
- Gigante, Bruna
- Kauhanen, Jussi
- Rauramaa, Rainer
- Smit, Andries J
- Mannarino, Elmo
- Giral, Philippe
- Humphries, Steve ...
- Tremoli, Elena
- de Faire, Ulf
- Ohrvik, John
- Nilsson, Jan
- Hamsten, Anders
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- Atherosclerosis
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- Lund University
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