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Genetic loci influencing kidney function and chronic kidney disease

Chambers, John C. (author)
Zhang, Weihua (author)
Lord, Graham M. (author)
show more...
van der Harst, Pim (author)
Lawlor, Debbie A. (author)
Sehmi, Joban S. (author)
Gale, Daniel P. (author)
Wass, Mark N. (author)
Ahmadi, Kourosh R. (author)
Bakker, Stephan J. L. (author)
Beckmann, Jacqui (author)
Bilo, Henk J. G. (author)
Bochud, Murielle (author)
Brown, Morris J. (author)
Caulfield, Mark J. (author)
Connell, John M. C. (author)
Cook, H. Terence (author)
Cotlarciuc, Ioana (author)
Smith, George Davey (author)
de Silva, Ranil (author)
Deng, Guohong (author)
Devuyst, Olivier (author)
Dikkeschei, Lambert D. (author)
Dimkovic, Nada (author)
Dockrell, Mark (author)
Dominiczak, Anna (author)
Ebrahim, Shah (author)
Eggermann, Thomas (author)
Farrall, Martin (author)
Ferrucci, Luigi (author)
Floege, Jurgen (author)
Forouhi, Nita G. (author)
Gansevoort, Ron T. (author)
Han, Xijin (author)
Hedblad, Bo (author)
Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups
van der Heide, Jaap J. Homan (author)
Hepkema, Bouke G. (author)
Hernandez-Fuentes, Maria (author)
Hypponen, Elina (author)
Johnson, Toby (author)
de Jong, Paul E. (author)
Kleefstra, Nanne (author)
Lagou, Vasiliki (author)
Lapsley, Marta (author)
Li, Yun (author)
Loos, Ruth J. F. (author)
Luan, Jian'an (author)
Luttropp, Karin (author)
Karolinska Institutet
Marechal, Celine (author)
Melander, Olle (author)
Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
Munroe, Patricia B. (author)
Nordfors, Louise (author)
Karolinska Institutet
Parsa, Afshin (author)
Peltonen, Leena (author)
Penninx, Brenda W. (author)
Perucha, Esperanza (author)
Pouta, Anneli (author)
Prokopenko, Inga (author)
Roderick, Paul J. (author)
Ruokonen, Aimo (author)
Samani, Nilesh J. (author)
Sanna, Serena (author)
Schalling, Martin (author)
Karolinska Institutet
Schlessinger, David (author)
Schlieper, Georg (author)
Seelen, Marc A. J. (author)
Shuldiner, Alan R. (author)
Sjögren, Marketa (author)
Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Kardiovaskulär forskning - hypertoni,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Cardiovascular Research - Hypertension
Smit, Johannes H. (author)
Snieder, Harold (author)
Soranzo, Nicole (author)
Spector, Timothy D. (author)
Stenvinkel, Peter (author)
Karolinska Institutet
Sternberg, Michael J. E. (author)
Swaminathan, Ramasamyiyer (author)
Tanaka, Toshiko (author)
Ubink-Veltmaat, Lielith J. (author)
Uda, Manuela (author)
Vollenweider, Peter (author)
Wallace, Chris (author)
Waterworth, Dawn (author)
Zerres, Klaus (author)
Waeber, Gerard (author)
Wareham, Nicholas J. (author)
Maxwell, Patrick H. (author)
McCarthy, Mark I. (author)
Jarvelin, Marjo-Riitta (author)
Mooser, Vincent (author)
Abecasis, Goncalo R. (author)
Lightstone, Liz (author)
Scott, James (author)
Navis, Gerjan (author)
Elliott, Paul (author)
Kooner, Jaspal S. (author)
show less...
 (creator_code:org_t)
2010-04-11
2010
English.
In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 42:5, s. 373-375
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10(-10) to 10(-15)). Of these, rs10206899 (near NAT8, 2p12-p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney disease (P = 5.0 x 10(-5) and P = 3.6 x 10(-4), respectively). Our findings provide insight into metabolic, solute and drug-transport pathways underlying susceptibility to chronic kidney disease.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

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art (subject category)
ref (subject category)

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By the author/editor
Chambers, John C ...
Zhang, Weihua
Lord, Graham M.
van der Harst, P ...
Lawlor, Debbie A ...
Sehmi, Joban S.
show more...
Gale, Daniel P.
Wass, Mark N.
Ahmadi, Kourosh ...
Bakker, Stephan ...
Beckmann, Jacqui
Bilo, Henk J. G.
Bochud, Murielle
Brown, Morris J.
Caulfield, Mark ...
Connell, John M. ...
Cook, H. Terence
Cotlarciuc, Ioan ...
Smith, George Da ...
de Silva, Ranil
Deng, Guohong
Devuyst, Olivier
Dikkeschei, Lamb ...
Dimkovic, Nada
Dockrell, Mark
Dominiczak, Anna
Ebrahim, Shah
Eggermann, Thoma ...
Farrall, Martin
Ferrucci, Luigi
Floege, Jurgen
Forouhi, Nita G.
Gansevoort, Ron ...
Han, Xijin
Hedblad, Bo
van der Heide, J ...
Hepkema, Bouke G ...
Hernandez-Fuente ...
Hypponen, Elina
Johnson, Toby
de Jong, Paul E.
Kleefstra, Nanne
Lagou, Vasiliki
Lapsley, Marta
Li, Yun
Loos, Ruth J. F.
Luan, Jian'an
Luttropp, Karin
Marechal, Celine
Melander, Olle
Munroe, Patricia ...
Nordfors, Louise
Parsa, Afshin
Peltonen, Leena
Penninx, Brenda ...
Perucha, Esperan ...
Pouta, Anneli
Prokopenko, Inga
Roderick, Paul J ...
Ruokonen, Aimo
Samani, Nilesh J ...
Sanna, Serena
Schalling, Marti ...
Schlessinger, Da ...
Schlieper, Georg
Seelen, Marc A. ...
Shuldiner, Alan ...
Sjögren, Marketa
Smit, Johannes H ...
Snieder, Harold
Soranzo, Nicole
Spector, Timothy ...
Stenvinkel, Pete ...
Sternberg, Micha ...
Swaminathan, Ram ...
Tanaka, Toshiko
Ubink-Veltmaat, ...
Uda, Manuela
Vollenweider, Pe ...
Wallace, Chris
Waterworth, Dawn
Zerres, Klaus
Waeber, Gerard
Wareham, Nichola ...
Maxwell, Patrick ...
McCarthy, Mark I ...
Jarvelin, Marjo- ...
Mooser, Vincent
Abecasis, Goncal ...
Lightstone, Liz
Scott, James
Navis, Gerjan
Elliott, Paul
Kooner, Jaspal S ...
show less...
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
Articles in the publication
Nature Genetics
By the university
Lund University
Karolinska Institutet

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