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Mortality in patien...
Mortality in patients with behavioural and psychological symptoms of dementia : a registry-based study
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- Bränsvik, Vanja (författare)
- Lund Univ, Sweden,Lund University
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- Granvik, Eva (författare)
- Skane Univ Hosp, Sweden,Skåne University Hospital
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- Minthon, Lennart (författare)
- Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,Skåne University Hospital
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- Nordström, Peter (författare)
- Umeå University,Umeå universitet,Geriatrik,Umea Univ, Sweden
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- Nägga, Katarina, 1962- (författare)
- Linköping University,Lund University,Lunds universitet,Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Medicinska och geriatriska akutkliniken,Lund Univ, Sweden,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups
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(creator_code:org_t)
- 2020-02-18
- 2021
- Engelska.
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Ingår i: Aging & Mental Health. - : Routledge. - 1360-7863 .- 1364-6915. ; 25:6, s. 1101-1109
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Abstract
Ämnesord
Stäng
- Objectives: Behavioural and psychological symptoms of dementia (BPSD) are common in patients with dementia. In the elderly population, comorbidities frequently coexist with dementia and mortality in dementia is high. The aim of this study was to investigate the impact of BPSD on mortality in severe dementia.Methods: This study of 11,448 individuals was based on linked information from the Swedish BPSD registry, the National Patient Register and the Cause of Death register. BPSD was assessed with the Neuropsychiatric Inventory (NPI). Cox proportional hazards regressions were performed for survival analysis. To study different degrees of BPSD, data was categorized into groups: no (NPI, 0 points), mild (NPI, 1-3 points on >= 1 item), moderate (NPI, 4-8 points on >= 1 item) and severe (NPI, 9-12 points on >= 1 item) BPSD based on the highest score on any of the BPSD assessed (NPI items).Results: The presence of moderate or severe BPSD was associated with a stepwise increased risk of mortality (hazard ratio (HR), 1.31; 95% confidence interval (CI), 1.08-1.60 and HR 1.74; 95% CI 1.44-2.12, respectively) compared with individuals with no BPSD. In addition, there was an association between total NPI score and mortality (HR 1.01; 95% CI 1.007-1.010). The results remained significant after multivariable adjustment for age, sex, dementia diagnosis, medication, previous myocardial infarction, hip fracture and stroke.Conclusions: The results show a stepwise increase in mortality risk with increased BPSD, highlighting the importance of adequate management of BPSD to reduce mortality in dementia.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
Nyckelord
- Behavioural and psychological symptoms of dementia
- mortality
- BPSD
- Neuropsychiatric Inventory
- nursing homes
- registry-based study
- Behavioural and psychological symptoms of dementia
- BPSD
- mortality
- Neuropsychiatric Inventory
- nursing homes
- registry-based study
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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