Heat-related cardiorespiratory mortality: effect modification by air pollution across 482 cities from 24 countries

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Heat-related cardiorespiratory mortality : effect modification by air pollution across 482 cities from 24 countries

Rai, Masna (författare): Institute of Epidemiology, Helmholtz Munich, - German Research Center for Environmental Health, Neuherberg, Germany; Institute for Medical Information Processing, Biometry, and Epidemiology – IBE, Pettenkofer School of Public Health, LMU Munich, Munich, Germany

Stafoggia, Massimo (författare): Department of Epidemiology, Lazio Regional Health Service, ASL Roma 1, Rome, Italy

de'Donato, Francesca (författare): Department of Epidemiology, Lazio Regional Health Service, ASL Roma 1, Rome, Italy

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Scortichini, Matteo (författare): Department of Epidemiology, Lazio Regional Health Service, ASL Roma 1, Rome, Italy

Zafeiratou, Sofia (författare): epartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Greece

Vazquez Fernandez, Liliana (författare): Department of Air Pollution and Noise, Norwegian Institute of Public Health, Oslo, Norway

Zhang, Siqi (författare): Institute of Epidemiology, Helmholtz Munich, - German Research Center for Environmental Health, Neuherberg, Germany

Katsouyanni, Klea (författare): epartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Greece

Samoli, Evangelia (författare): epartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Greece

Rao, Shilpa (författare): Department of Air Pollution and Noise, Norwegian Institute of Public Health, Oslo, Norway

Lavigne, Eric (författare): School of Epidemiology & Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada and Environmental Health Science & Research Bureau, Health Canada, Ottawa, Canada

Guo, Yuming (författare): Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

Kan, Haidong (författare): Department of Environmental Health, School of Public Health, Fudan University, Shanghai, China

Osorio, Samuel (författare): Department of Environmental Health, University of São Paulo, São Paulo, Brazil

Kyselý, Jan (författare): Institute of Atmospheric Physics, Czech Academy of Sciences, Prague, Czech Republic Faculty of Environmental Sciences, Czech University of Life Sciences, Prague, Czech Republic

Urban, Aleš (författare): Institute of Atmospheric Physics, Czech Academy of Sciences, Prague, Czech Republic Faculty of Environmental Sciences, Czech University of Life Sciences, Prague, Czech Republic

Orru, Hans (författare): Department of Family Medicine and Public Health, University of Tartu, Tartu, Estonia

Maasikmets, Marek (författare): Estonian Environmental Research Centre, Tallinn, Estonia

Jaakkola, Jouni J.K. (författare): Center for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland

Ryti, Niilo (författare): Center for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland

Pascal, Mathilde (författare): Santé Publique France, Department of Environmental Health, French National Public Health Agency, Saint Maurice, France

Hashizume, Masahiro (författare): Department of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Fook Sheng Ng, Chris (författare): School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan

Alahmad, Barrak (författare): Department of Environmental Health, Harvard T.H. Chan School of Public Health, MA, Boston, United States

Hurtado Diaz, Magali (författare): Department of Environmental Health, National Institute of Public Health, Morelos, Cuernavaca, Mexico

De la Cruz Valencia, César (författare): Department of Environmental Health, National Institute of Public Health, Morelos, Cuernavaca, Mexico

Nunes, Baltazar (författare): Department of Environmental Health, Instituto Nacional de Saúde Dr. Ricardo Jorge, Porto, Portugal

Madureira, Joana (författare): Department of Environmental Health, Instituto Nacional de Saúde Dr. Ricardo Jorge, Porto, Portugal

Scovronick, Noah (författare): Department of Environmental Health. Rollins School of Public Health, Emory University, Atlanta, United States

Garland, Rebecca M. (författare): Department of Geography, Geoinformatics and Meteorology, University of Pretoria, Pretoria, South Africa

Kim, Ho (författare): Graduate School of Public Health, Seoul National University, Seoul, South Korea

Lee, Whanhee (författare): School of Biomedical Convergence Engineering, Pusan National University, Yangsan, South Korea

Tobias, Aurelio (författare): Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council for Scientific Research (CSIC), Barcelona, Spain

Íñiguez, Carmen (författare): Department of Statistics and Computational Research, Universitat de València, València, Spain

Forsberg, Bertil, professor, 1956- (författare): Umeå universitet,Institutionen för folkhälsa och klinisk medicin

Åström, Christofer, 1983- (författare): Umeå universitet,Institutionen för folkhälsa och klinisk medicin

Maria Vicedo-Cabrera, Ana (författare): Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland

Ragettli, Martina S. (författare): Swiss Tropical and Public Health Institute, Basel, Switzerland

Leon Guo, Yue-Liang (författare): Environmental and Occupational Medicine, Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University (NTU) and NTU Hospital, Taipei, Taiwan

Pan, Shih-Chun (författare): National Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan

Li, Shanshan (författare): Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

Gasparrini, Antonio (författare): Department of Public Health Environments and Society, London School of Hygiene & Tropical Medicine, London, United Kingdom

Sera, Francesco (författare): Department of Statistics, Computer Science and Applications “G. Parenti”, University of Florence, Florence, Italy

Masselot, Pierre (författare): Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

Schwartz, Joel (författare): Department of Environmental Health, Harvard T.H. Chan School of Public Health, MA, Boston, United States

Zanobetti, Antonella (författare): Department of Environmental Health, Harvard T.H. Chan School of Public Health, MA, Boston, United States

Bell, Michelle L. (författare): School of Forestry and Environmental Studies, Yale University, CT, New Haven, United States

Schneider, Alexandra (författare): Institute of Epidemiology, Helmholtz Munich, - German Research Center for Environmental Health, Neuherberg, Germany

Breitner, Susanne (författare): Institute of Epidemiology, Helmholtz Munich, - German Research Center for Environmental Health, Neuherberg, Germany; Institute for Medical Information Processing, Biometry, and Epidemiology – IBE, Pettenkofer School of Public Health, LMU Munich, Munich, Germany

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Elsevier, 2023
2023
Engelska.
Ingår i: Environment International. - : Elsevier. - 0160-4120 .- 1873-6750. ; 174

Relaterad länk:: https://doi.org/10.1...; visa fler...; https://umu.diva-por... (primary) (Raw object); https://urn.kb.se/re...; https://doi.org/10.1...; visa färre...

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Background: Evidence on the potential interactive effects of heat and ambient air pollution on cause-specific mortality is inconclusive and limited to selected locations. Objectives: We investigated the effects of heat on cardiovascular and respiratory mortality and its modification by air pollution during summer months (six consecutive hottest months) in 482 locations across 24 countries.Methods: Location-specific daily death counts and exposure data (e.g., particulate matter with diameters ≤ 2.5 µm [PM2.5]) were obtained from 2000 to 2018. We used location-specific confounder-adjusted Quasi-Poisson regression with a tensor product between air temperature and the air pollutant. We extracted heat effects at low, medium, and high levels of pollutants, defined as the 5th, 50th, and 95th percentile of the location-specific pollutant concentrations. Country-specific and overall estimates were derived using a random-effects multilevel meta-analytical model.Results: Heat was associated with increased cardiorespiratory mortality. Moreover, the heat effects were modified by elevated levels of all air pollutants in most locations, with stronger effects for respiratory than cardiovascular mortality. For example, the percent increase in respiratory mortality per increase in the 2-day average summer temperature from the 75th to the 99th percentile was 7.7% (95% Confidence Interval [CI] 7.6–7.7), 11.3% (95%CI 11.2–11.3), and 14.3% (95% CI 14.1–14.5) at low, medium, and high levels of PM2.5, respectively. Similarly, cardiovascular mortality increased by 1.6 (95%CI 1.5–1.6), 5.1 (95%CI 5.1–5.2), and 8.7 (95%CI 8.7–8.8) at low, medium, and high levels of O3, respectively.Discussion: We observed considerable modification of the heat effects on cardiovascular and respiratory mortality by elevated levels of air pollutants. Therefore, mitigation measures following the new WHO Air Quality Guidelines are crucial to enhance better health and promote sustainable development.

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Av författaren/redakt...: Rai, Masna; Stafoggia, Massi ...; de'Donato, Franc ...; Scortichini, Mat ...; Zafeiratou, Sofi ...; Vazquez Fernande ...; visa fler...; Zhang, Siqi; Katsouyanni, Kle ...; Samoli, Evangeli ...; Rao, Shilpa; Lavigne, Eric; Guo, Yuming; Kan, Haidong; Osorio, Samuel; Kyselý, Jan; Urban, Aleš; Orru, Hans; Maasikmets, Mare ...; Jaakkola, Jouni ...; Ryti, Niilo; Pascal, Mathilde; Hashizume, Masah ...; Fook Sheng Ng, C ...; Alahmad, Barrak; Hurtado Diaz, Ma ...; De la Cruz Valen ...; Nunes, Baltazar; Madureira, Joana; Scovronick, Noah; Garland, Rebecca ...; Kim, Ho; Lee, Whanhee; Tobias, Aurelio; Íñiguez, Carmen; Forsberg, Bertil ...; Åström, Christof ...; Maria Vicedo-Cab ...; Ragettli, Martin ...; Leon Guo, Yue-Li ...; Pan, Shih-Chun; Li, Shanshan; Gasparrini, Anto ...; Sera, Francesco; Masselot, Pierre; Schwartz, Joel; Zanobetti, Anton ...; Bell, Michelle L ...; Schneider, Alexa ...; Breitner, Susann ...; visa färre...

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Av lärosätet: Umeå universitet

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Heat-related cardiorespiratory mortality : effect modification by air pollution across 482 cities from 24 countries

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