Polarization anisotropy of DNA in nanochannels

• The local alignment of DNA stretched in nanofluidic channels is measured using polarization sensitive detection. With increased degree of stretching the polarization anisotropy increases both in the deGennes and the Odijk regime. The technique is expected to find use in studies of, for example, local conformational changes in polymer physics in confined spaces, studies of protein-DNA interactions and compactation of DNA.

Nyckelord

Nanofluidics

Optics

Polarization anisotropy

Polymer physics

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