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Multiple myeloma ri...
Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts
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Hvidtfeldt, Ulla Arthur (author)
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Chen, Jie (author)
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Rodopoulou, Sophia (author)
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Strak, Maciej (author)
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de Hoogh, Kees (author)
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- Bellander, Tom (author)
- Karolinska Institutet
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Brandt, J. orgen (author)
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Forastiere, Francesco (author)
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- Brynedal, Boel (author)
- Karolinska Institutet
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Hertel, Ole (author)
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Hoffmann, Barbara (author)
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- Katsouyanni, Klea (author)
- Karolinska Institutet
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Ketzel, Matthias (author)
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Leander, Karin (author)
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Magnusson, Patrik K. E. (author)
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Nagel, Gabriele (author)
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- Pershagen, Goran (author)
- Karolinska Institutet
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- Rizzuto, Debora (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),tockholm Gerontology Research Center, Sweden
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Samoli, Evangelia (author)
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So, Rina (author)
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Stafoggia, Massimo (author)
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Onneland, Anne Tj (author)
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Weinmayr, Gudrun (author)
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Wolf, Kathrin (author)
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Zitt, Emanuel (author)
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Brunekreef, Bert (author)
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Hoek, Gerard (author)
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Raaschou-Nielsen, Ole (author)
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(creator_code:org_t)
- 2023
- 2023
- English.
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In: Environmental Research. - 0013-9351 .- 1096-0953. ; 239:1
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- Background: Air pollution is a growing concern worldwide, with significant impacts on human health. Multiple myeloma is a type of blood cancer with increasing incidence. Studies have linked air pollution exposure to various types of cancer, including leukemia and lymphoma, however, the relationship with multiple myeloma incidence has not been extensively investigated. Methods: We pooled four European cohorts (N = 234,803) and assessed the association between residential exposure to nitrogen dioxide (NO2), fine particles (PM2.5), black carbon (BC), and ozone (O3) and multiple myeloma. We applied Cox proportional hazards models adjusting for potential confounders at the individual and area-level. Results: During 4,415,817 person-years of follow-up (average 18.8 years), we observed 404 cases of multiple myeloma. The results of the fully adjusted linear analyses showed hazard ratios (95% confidence interval) of 0.99 (0.84, 1.16) per 10 mu g/m3 NO2, 1.04 (0.82, 1.33) per 5 mu g/m3 PM2.5, 0.99 (0.84, 1.18) per 0.5 10- 5 m-1 BCE, and 1.11 (0.87, 1.41) per 10 mu g/m3 O3. Conclusions: We did not observe an association between long-term ambient air pollution exposure and incidence of multiple myeloma.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Keyword
- Air pollution
- Multiple myeloma
- Nitrogen dioxide
- Particulate matter
- Ozone
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Hvidtfeldt, Ulla ...
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Chen, Jie
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Rodopoulou, Soph ...
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Strak, Maciej
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de Hoogh, Kees
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Bellander, Tom
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show more...
-
Brandt, J. orgen
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Forastiere, Fran ...
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Brynedal, Boel
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Hertel, Ole
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Hoffmann, Barbar ...
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Katsouyanni, Kle ...
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Ketzel, Matthias
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Leander, Karin
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Magnusson, Patri ...
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Nagel, Gabriele
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Pershagen, Goran
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Rizzuto, Debora
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Samoli, Evangeli ...
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So, Rina
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Stafoggia, Massi ...
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Onneland, Anne T ...
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Weinmayr, Gudrun
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Wolf, Kathrin
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Zitt, Emanuel
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Brunekreef, Bert
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Hoek, Gerard
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Raaschou-Nielsen ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Hematology
- Articles in the publication
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Environmental Re ...
- By the university
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Stockholm University
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Karolinska Institutet