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Contrasting Carbohy...
Contrasting Carbohydrate Quantity and Quality and the Effects on Plasma Saturated and Monounsaturated Fatty Acids in Healthy Adults : A Randomized Controlled Trial
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- Bajahzer, Mohammed F. (författare)
- Uppsala universitet,Klinisk nutrition och metabolism,Jazan Univ, Fac Appl Med Sci, Dept Clin Nutr, Jazan, Saudi Arabia.
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- Rosqvist, Fredrik, 1985- (författare)
- Uppsala universitet,Klinisk nutrition och metabolism
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- Fridén, Michael (författare)
- Uppsala universitet,Klinisk nutrition och metabolism
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- Iggman, David (författare)
- Uppsala universitet,Klinisk nutrition och metabolism
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- Pingel, Ronnie, 1978- (författare)
- Uppsala universitet,Klinisk nutrition och metabolism
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- Marklund, Matti (författare)
- Uppsala universitet,Klinisk nutrition och metabolism,UNSW Sydney, George Inst Global Hlth, Fac Med, Sydeny, NSW, Australia.;Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.
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- Risérus, Ulf, 1967- (författare)
- Uppsala universitet,Klinisk nutrition och metabolism
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(creator_code:org_t)
- Elsevier, 2023
- 2023
- Engelska.
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Ingår i: Journal of Nutrition. - : Elsevier. - 0022-3166 .- 1541-6100. ; 153:3, s. 683-690
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: It is unclear whether moderate differences in dietary carbohydrate quantity and quality influence plasma FAs in the lipogenic pathway in healthy adults.Objectives: We investigated the effects of different carbohydrate quantities and quality on plasma palmitate concentrations (primary outcome) and other saturated and MUFAs in the lipogenic pathway.Methods: Twenty healthy participants were randomly assigned, and 18 (50% women; age: 22-72 y; BMI: 18.2-32.7 kg/m2 and BMI was measured in kg/m2) started the cross-over intervention. During each 3-wk period (separated by a 1-wk washout period), 3 diets were consumed (all foods provided) in random order: low-carbohydrate (LC) (38% energy (E) carbohydrates, 25-35 g fiber/d, 0% E added sugars); high-carbohydrate/high-fiber (HCF) (53% E carbohydrates, 25-35 g fiber/d, 0% E added sugars); and high-carbohydrate/high-sugar (HCS) (53% E carbohydrates, 19-21 g fiber/d, 15% E added sugars). Individual FAs were measured proportionally to total FAs by GC in plasma cholesteryl esters, phospholipids, and TGs. False discovery rate-adjusted repeated measures ANOVA [ANOVA-false discovery rate (FDR)] was used to compare outcomes.Results: The self-reported intakes of carbohydrates and added-and free sugars were; 30.6% E and 7.4% E in LC, 41.4% E and 6.9% E in HCF, and 45.7% E and 10.3% in HCS. Plasma palmitate did not differ between the diet periods (ANOVA FDR P > 0.43, n = 18). After HCS, myristate concentrations in cholesterol esters and phospholipids were >= 19% higher than LC and >= 22% higher than HCF (P = 0.005). After LC, palmitoleate in TG was 6% lower compared with HCF and 7% compared with HCS (P = 0.041). Body weight differed (<= 0.75 kg) between diets before FDR correction.Conclusions: Different carbohydrate quantity and quality do not influence plasma palmitate concentrations after 3 wk in healthy Swedish adults, whereas myristate increased after the moderately higher intake of carbohydrate/high-sugar, but not carbohydrate/high-fiber. Whether plasma myristate is more responsive than palmitate to differences in carbohydrate intake requires further study, especially considering that participants deviated from the planned dietary targets.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Nyckelord
- carbohydrate intake
- palmitate
- palmitoleate
- plasma fatty acids
- randomized controlled trial
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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